Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing von Campbell, Peter J, Pleasance, Erin D, Stephens, Philip J, Dicks, Ed, Rance, Richard, Goodhead, Ian, Follows, George A, Green, Anthony R, Futreal, P. Andy, Stratton, Michael R

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Donor clonal hematopoiesis increases risk of acute graft versus host disease after matched sibling transplantation von Oran, Betül, Champlin, Richard E., Wang, Feng, Tanaka, Tomoyuki, Saliba, Rima M., Al-Atrash, Gheath, Garcia-Manero, Guillermo, Kantarjian, Hagop, Cao, Kai, Shpall, Elizabeth J., Alousi, Amin M., Mehta, Rohtesh S., Popat, Uday, Futreal, Andy, Takahashi, Koichi

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The somatic genetic architecture of human cancer: heterogeneity and the challenges for translational medicine von Futreal, Andy

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Mouse‐INtraDuctal (MIND): an in vivo model for studying the underlying mechanisms of DCIS malignancy von Hong, Yan, Limback, Darlene, Elsarraj, Hanan S, Harper, Haleigh, Haines, Haley, Hansford, Hayley, Ricci, Michael, Kaufman, Carolyn, Wedlock, Emily, Xu, Mingchu, Zhang, Jianhua, May, Lisa, Cusick, Therese, Inciardi, Marc, Redick, Mark, Gatewood, Jason, Winblad, Onalisa, Aripoli, Allison, Huppe, Ashley, Balanoff, Christa, Wagner, Jamie L, Amin, Amanda L, Larson, Kelsey E, Ricci, Lawrence, Tawfik, Ossama, Razek, Hana, Meierotto, Ruby O, Madan, Rashna, Godwin, Andrew K, Thompson, Jeffrey, Hilsenbeck, Susan G, Futreal, Andy, Thompson, Alastair, Hwang, E Shelley, Fan, Fang, Behbod, Fariba

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Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance von Fan, Huihui, Wang, Feng, Zeng, Andy, Murison, Alex, Tomczak, Katarzyna, Hao, Dapeng, Jelloul, Fatima Zahra, Wang, Bofei, Barrodia, Praveen, Liang, Shaoheng, Chen, Ken, Wang, Linghua, Zhao, Zhongming, Rai, Kunal, Jain, Abhinav K., Dick, John, Daver, Naval, Futreal, Andy, Abbas, Hussein A.

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Her2-Targeted Therapies in Non–Small Cell Lung Cancer von SWANTON, Charles, FUTREAL, Andy, EISEN, Tim

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Netie: inferring the evolution of neoantigen–T cell interactions in tumors von Lu, Tianshi, Park, Seongoh, Han, Yi, Wang, Yunguan, Hubert, Shawna Marie, Futreal, P. Andy, Wistuba, Ignacio, Heymach, John V., Reuben, Alexandre, Zhang, Jianjun, Wang, Tao

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Mutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans von Wu, Ye, Arai, Amy C, Rumbaugh, Gavin, Srivastava, Anand K, Turner, Gillian, Hayashi, Takashi, Suzuki, Erika, Jiang, Yuwu, Zhang, Lilei, Rodriguez, Jayson, Boyle, Jackie, Tarpey, Patrick, Raymond, F. Lucy, Nevelsteen, Joke, Froyen, Guy, Stratton, Mike, Futreal, Andy, Gecz, Jozef, Stevenson, Roger, Schwartz, Charles E, Valle, David, Huganir, Richard L, Wang, Tao

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The Mutational Profile of Plasma Cell Disorders von Futreal, Andy

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PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data von Greenman, Chris D., Bignell, Graham, Butler, Adam, Edkins, Sarah, Hinton, Jon, Beare, Dave, Swamy, Sajani, Santarius, Thomas, Chen, Lina, Widaa, Sara, Futreal, P. Andy, Stratton, Michael R.

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Abstract 3489: Comprehensive characterization of the SLC transporters in human cancer von Wang, Ruiping, Zhang, Shaojun, Futreal, Andy, Wang, Linghua

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Single-Cell Profiling of CD8 Landscape in Treatment Naïve and Relapsed/Refractory AML Patients Reveals Distinct Effector Cellular States Predictive of Outcomes von Desai, Poonam, Wang, Bofei, Jelloul, Fatima Zahra, Alatrash, Gheath, Baran, Natalia, Deng, Qing, Green, Michael R, Daver, Naval, Konopleva, Marina, Futreal, Andy, Hao, Dapeng, Abbas, Hussein A

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BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells von Khaled, Walid T., Choon Lee, Song, Stingl, John, Chen, Xiongfeng, Raza Ali, H., Rueda, Oscar M., Hadi, Fazal, Wang, Juexuan, Yu, Yong, Chin, Suet-Feung, Stratton, Mike, Futreal, Andy, Jenkins, Nancy A., Aparicio, Sam, Copeland, Neal G., Watson, Christine J., Caldas, Carlos, Liu, Pentao

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Single Cell RNA-Seq Reveals Intra-Tumoral Heterogeneity Relevant to Differentiation States and Outcomes Among Newly Diagnosed Acute Myeloid Leukemia Patients von Wang, Bofei, Jelloul, Fatima Zahra, Borges, Pamella, Desai, Poonam, Tang, Guilin, Konopleva, Marina, Baran, Natalia, Green, Michael R, Deng, Qing, Daver, Naval, Futreal, Andy, Hao, Dapeng, Abbas, Hussein A

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Characterization of Dysregulated Transcription in TP53-Mutated AML Subpopulations von Issa, Ghayas C., Mohanty, Vakul, Ayoub, Edward, Wang, Feng, Leighton, Jake, Wu, Xiaogang, Bidikian, Aram, Patsilevas, Tallie, Alaniz, Zoe, Zarka, Jabra, Kanagal-Shamanna, Rashmi, Futreal, Andy, Daver, Naval, Konopleva, Marina, Navin, Nicholas, Zhang, Jianhua, Chen, Ken, Andreeff, Michael

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Somatic Mutations in TP53 Identified in T-Cells of Patients with TP53-mutated AML von Issa, Ghayas C., Bidikian, Aram, Ayoub, Edward, Wang, Feng, Mohanty, Vakul, Leighton, Jake, Wu, Xiaogang, Patsilevas, Tallie, Alaniz, Zoe, Zarka, Jabra, Kanagal-Shamanna, Rashmi, Daver, Naval, Futreal, Andy, Konopleva, Marina, Navin, Nicholas, Zhang, Jianhua, Chen, Ken, Andreeff, Michael

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Pilot Clinical Trial of Perioperative Durvalumab and Tremelimumab in the Treatment of Resectable Colorectal Cancer Liver Metastases von Kanikarla Marie, Preeti, Haymaker, Cara, Parra, Edwin Roger, Kim, Young Uk, Lazcano, Rossana, Gite, Swati, Lorenzini, Daniele, Wistuba, Ignacio I, Tidwell, Rebecca S Slack, Song, Xiaofei, Foo, Wai Chin, Maru, Dipen M, Chun, Yun Shin, Futreal, Andy, Kee, Bryan, Menter, David, Solis, Luisa, Tzeng, Ching-Wei, Parseghian, Christine, Raghav, Kanwal, Morris, Van, Chang, Chia-Chi, Jenq, Robert, Tam, Alda, Bernatchez, Chantale, Kopetz, Scott, Vauthey, Jean-Nicolas, Overman, Michael J

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Hypomethylating Agents Do Not Alter Novel Splicing Events in Myeloid Neoplasms von Abbas, Hussein A, Wang, Feng, Wei, Yue, Yang, Hui, Montalban Bravo, Guillermo, Kanagal-Shamanna, Rashmi, Class, Caleb, Darbaniyan, Faezeh, Zhang, Jianhua, Futreal, Andy, Garcia-Manero, Guillermo

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IFNγ Signaling in Acute Myeloid Leukemia Mediates Immunomodulation and Reveals Therapeutic Strategies von Wang, Bofei, Reville, Patrick K, Jelloul, Fatima Z, Desai, Poonam N, Borges, Pamella, Ly, Christopher, Veletic, Ivo, Dasdemir, Enes, Burks, Jared K., Tang, Guilin, Guo, Shengnan, Vaugh, Nicole, Baran, Natalia, Deng, Qing, Matthews, Jairo, Gunaratne, Preethi, Antunes, Dinler A, Ekmekcioglu, Suhendan, Sasaki, Koji, Garcia, Miriam B., Cuglievan, Branko, Hao, Dapeng, Daver, Naval, Green, Michael R., Konopleva, Marina Y., Futreal, Andy, Post, Sean M., Abbas, Hussein A

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Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders von BAXTER, E, SCOTT, L, CAMPBELL, P, EAST, C, FOUROUCLAS, N, SWANTON, S, VASSILIOU, G, BENCH, A, BOYD, E, CURTIN, N

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