Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation von Fernandez-Nogueira, Patricia, Mancino, Mario, Fuster, Gemma, Lopez-Plana, Anna, Jauregui, Patricia, Almendro, Vanesa, Enreig, Estel, Menendez, Silvia, Rojo, Federico, Noguera-Castells, Aleix, Bill, Anke, Gaither, L. Alex, Serrano, Laia, Recalde-Percaz, Leire, Moragas, Nuria, Alonso, Raul, Ametller, Elisabet, Rovira, Ana, Lluch, Ana, Albanell, Joan, Gascon, Pere, Bragado, Paloma

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Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma von Ikemori, Rafael, Gabasa, Marta, Duch, Paula, Vizoso, Miguel, Bragado, Paloma, Arshakyan, Marselina, Luis, Iuliana-Cristiana, Marin, Albert, Moran, Sebastian, Castro, Manuel, Fuster, Gemma, Gea-Sorli, Sabrina, Jauset, Toni, Soucek, Laura, Montuenga, Luis M., Esteller, Manel, Mons, Eduard, Peinado, Victor Ivo, Gascon, Pere, Fillat, Cristina, Hilberg, Frank, Reguart, Noemi, Alcaraz, Jordi

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The SEMA3F-NRP1/NRP2 axis is a key factor in the acquisition of invasive traits in in situ breast ductal carcinoma von Moragas, Núria, Fernandez-Nogueira, Patricia, Recalde-Percaz, Leire, Inman, Jamie L, López-Plana, Anna, Bergholtz, Helga, Noguera-Castells, Aleix, Del Burgo, Pedro J, Chen, Xieng, Sorlie, Therese, Gascón, Pere, Bragado, Paloma, Bissell, Mina, Carbó, Neus, Fuster, Gemma

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In Vitro and In Vivo Effects of the Combination of Polypurine Reverse Hoogsteen Hairpins against HER-2 and Trastuzumab in Breast Cancer Cells von López-Aguilar, Ester, Fernández-Nogueira, Patricia, Fuster, Gemma, Carbó, Neus, Ciudad, Carlos J, Noé, Véronique

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The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase von Erazo, Tatiana, Lorente, Mar, López-Plana, Anna, Muñoz-Guardiola, Pau, Fernández-Nogueira, Patricia, García-Martínez, José A, Bragado, Paloma, Fuster, Gemma, Salazar, María, Espadaler, Jordi, Hernández-Losa, Javier, Bayascas, Jose Ramon, Cortal, Marc, Vidal, Laura, Gascón, Pedro, Gómez-Ferreria, Mariana, Alfón, José, Velasco, Guillermo, Domènech, Carles, Lizcano, Jose M

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Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis von Zubeldia-Plazaola, Arantzazu, Recalde-Percaz, Leire, Moragas, Núria, Alcaraz, Mireia, Chen, Xieng, Mancino, Mario, Fernández-Nogueira, Patricia, Prats de Puig, Miquel, Guzman, Flavia, Noguera-Castells, Aleix, López-Plana, Anna, Enreig, Estel, Carbó, Neus, Almendro, Vanessa, Gascón, Pedro, Bragado, Paloma, Fuster, Gemma

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Barrier-protective effects of activated protein C in human alveolar epithelial cells von Puig, Ferranda, Fuster, Gemma, Adda, Mélanie, Blanch, Lluís, Farre, Ramon, Navajas, Daniel, Artigas, Antonio

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Substance P Autocrine Signaling Contributes to Persistent HER2 Activation That Drives Malignant Progression and Drug Resistance in Breast Cancer von GARCIA-RECIO, Susana, FUSTER, Gemma, ENGEL, Pablo, COSTAMAGNA, Domiziana, FERNANDEZ, Pedro L, GASCÓN, Pedro, ALMENDRO, Vanessa, FERNANDEZ-NOGUEIRA, Patricia, PASTOR-ARROYO, Eva M, SO YEON PARK, MAYORDOMO, Cristina, AMETLLER, Elisabet, MANCINO, Mario, GONZALEZ-FARRE, Xavier, RUSSNES, Hege G

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Differential Voltage-dependent K+ Channel Responses during Proliferation and Activation in Macrophages von Vicente, Rubén, Escalada, Artur, Coma, Mireia, Fuster, Gemma, Sánchez-Tilló, Ester, López-Iglesias, Carmen, Soler, Concepció, Solsona, Carles, Celada, Antonio, Felipe, Antonio

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Interleukin-15 Affects Differentiation and Apoptosis in Adipocytes: Implications in Obesity von Fuster, Gemma, Almendro, Vanessa, Fontes-Oliveira, Cibely Cristine, Toledo, Míriam, Costelli, Paola, Busquets, Sílvia, López-Soriano, Francisco J., Argilés, Josep M.

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Comparison of methods for the isolation of human breast epithelial and myoepithelial cells von Zubeldia-Plazaola, Arantzazu, Ametller, Elisabet, Mancino, Mario, Prats de Puig, Miquel, López-Plana, Anna, Guzman, Flavia, Vinyals, Laia, Pastor-Arroyo, Eva M, Almendro, Vanessa, Fuster, Gemma, Gascón, Pedro

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Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung von Lugo, Roberto, Gabasa, Marta, Andriani, Francesca, Puig, Marta, Facchinetti, Federica, Ramírez, Josep, Gómez-Caro, Abel, Pastorino, Ugo, Fuster, Gemma, Almendros, Isaac, Gascón, Pere, Davalos, Albert, Reguart, Noemí, Roz, Luca, Alcaraz, Jordi

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Effects of IL-15 on Rat Brown Adipose Tissue: Uncoupling Proteins and PPARs von Almendro, Vanessa, Fuster, Gemma, Busquets, Sílvia, Ametller, Elisabet, Figueras, Maite, Argilés, Josep M., López‐Soriano, Francisco J.

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Antiproteolytic effects of plasma from hibernating bears: A new approach for muscle wasting therapy? von Fuster, Gemma, Busquets, Sílvia, Almendro, Vanessa, López-Soriano, Francisco J, Argilés, Josep M

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Cancer-Associated Fibroblasts in Breast Cancer Treatment Response and Metastasis von Fernandez-Nogueira, Patricia, Fuster, Gemma, Gutierrez-Uzquiza, Alvaro, Gascon, Pere, Carbo, Neus, Bragado, Paloma

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In Vitro Evaluation of Oncogenic Transformation in Human Mammary Epithelial Cells von Repullés, Joan, Terradas, Mariona, Fuster, Gemma, Genescà, Anna, Anglada, Teresa

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Predictive capacity for local disease control of neogenin-1 (NEO1) transcriptional expression in patients with head and neck squamous cell carcinoma von León, Xavier, Valero, Cristina, Fuster, Gemma, Bragado, Paloma, Camacho, Mercedes, Avilés-Jurado, Francesc-Xavier

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Histamine receptor 1 inhibition enhances antitumor therapeutic responses through extracellular signal-regulated kinase (ERK) activation in breast cancer von Fernández-Nogueira, Patricia, Noguera-Castells, Aleix, Fuster, Gemma, Recalde-Percaz, Leire, Moragas, Núria, López-Plana, Anna, Enreig, Estel, Jauregui, Patricia, Carbó, Neus, Almendro, Vanessa, Gascón, Pedro, Bragado, Paloma, Mancino, Mario

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Heterogeneity of breast cancer: etiology and clinical relevance von Almendro, Vanessa, Fuster, Gemma

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Abstract 2138: Understanding the microenvironment contribution to ductal carcinoma in situ transition to invasiveness in breast cancer von Moragas, Núria, Recalde-Percaz, Leire, Noguera-Castells, Aleix, Fernandez-Nogueira, Patricia, Mancino, Mario, Gascón, Pedro, Fuster, Gemma

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