Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor von Antal, Corina E., Hudson, Andrew M., Kang, Emily, Zanca, Ciro, Wirth, Christopher, Stephenson, Natalie L., Trotter, Eleanor W., Gallegos, Lisa L., Miller, Crispin J., Furnari, Frank B., Hunter, Tony, Brognard, John, Newton, Alexandra C.

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Heterogeneity Maintenance in Glioblastoma: A Social Network von BONAVIA, Rudy, INDA, Maria-Del-Mar, CAVENEE, Webster K, FURNARI, Frank B

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An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers von Villa, Genaro R., Hulce, Jonathan J., Zanca, Ciro, Bi, Junfeng, Ikegami, Shiro, Cahill, Gabrielle L., Gu, Yuchao, Lum, Kenneth M., Masui, Kenta, Yang, Huijun, Rong, Xin, Hong, Cynthia, Turner, Kristen M., Liu, Feng, Hon, Gary C., Jenkins, David, Martini, Michael, Armando, Aaron M., Quehenberger, Oswald, Cloughesy, Timothy F., Furnari, Frank B., Cavenee, Webster K., Tontonoz, Peter, Gahman, Timothy C., Shiau, Andrew K., Cravatt, Benjamin F., Mischel, Paul S.

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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling von Bi, Junfeng, Ichu, Taka-Aki, Zanca, Ciro, Yang, Huijun, Zhang, Wei, Gu, Yuchao, Chowdhry, Sudhir, Reed, Alex, Ikegami, Shiro, Turner, Kristen M., Zhang, Wenjing, Villa, Genaro R., Wu, Sihan, Quehenberger, Oswald, Yong, William H., Kornblum, Harley I., Rich, Jeremy N., Cloughesy, Timothy F., Cavenee, Webster K., Furnari, Frank B., Cravatt, Benjamin F., Mischel, Paul S.

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EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling von Liu, Feng, Hon, Gary C., Villa, Genaro R., Turner, Kristen M., Ikegami, Shiro, Yang, Huijun, Ye, Zhen, Li, Bin, Kuan, Samantha, Lee, Ah Young, Zanca, Ciro, Wei, Bowen, Lucey, Greg, Jenkins, David, Zhang, Wei, Barr, Cathy L., Furnari, Frank B., Cloughesy, Timothy F., Yong, William H., Gahman, Timothy C., Shiau, Andrew K., Cavenee, Webster K., Ren, Bing, Mischel, Paul S.

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Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA von Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Estin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.

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Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development von Binder, Zev A., Thorne, Amy Haseley, Bakas, Spyridon, Wileyto, E. Paul, Bilello, Michel, Akbari, Hamed, Rathore, Saima, Ha, Sung Min, Zhang, Logan, Ferguson, Cole J., Dahiya, Sonika, Bi, Wenya Linda, Reardon, David A., Idbaih, Ahmed, Felsberg, Joerg, Hentschel, Bettina, Weller, Michael, Bagley, Stephen J., Morrissette, Jennifer J.D., Nasrallah, MacLean P., Ma, Jianhui, Zanca, Ciro, Scott, Andrew M., Orellana, Laura, Davatzikos, Christos, Furnari, Frank B., O'Rourke, Donald M.

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MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells von Talukdar, Sarmistha, Pradhan, Anjan K., Bhoopathi, Praveen, Shen, Xue-Ning, August, Laura A., Windle, Jolene J., Sarkar, Devanand, Furnari, Frank B., Cavenee, Webster K., Das, Swadesh K., Emdad, Luni, Fisher, Paul B.

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Malignant astrocytic glioma: genetics, biology, and paths to treatment von Furnari, Frank B, Fenton, Tim, Bachoo, Robert M, Mukasa, Akitake, Stommel, Jayne M, Stegh, Alexander, Hahn, William C, Ligon, Keith L, Louis, David N, Brennan, Cameron, Chin, Lynda, DePinho, Ronald A, Cavenee, Webster K

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PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3 von Benitez, Jorge A., Ma, Jianhui, D’Antonio, Matteo, Boyer, Antonia, Camargo, Maria Fernanda, Zanca, Ciro, Kelly, Stephen, Khodadadi-Jamayran, Alireza, Jameson, Nathan M., Andersen, Michael, Miletic, Hrvoje, Saberi, Shahram, Frazer, Kelly A., Cavenee, Webster K., Furnari, Frank B.

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The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-) von Tsuchihashi, Kenji, Okazaki, Shogo, Ohmura, Mitsuyo, Ishikawa, Miyuki, Sampetrean, Oltea, Onishi, Nobuyuki, Wakimoto, Hiroaki, Yoshikawa, Momoko, Seishima, Ryo, Iwasaki, Yoshimi, Morikawa, Takayuki, Abe, Shinya, Takao, Ayumi, Shimizu, Misato, Masuko, Takashi, Nagane, Motoo, Furnari, Frank B, Akiyama, Tetsu, Suematsu, Makoto, Baba, Eishi, Akashi, Koichi, Saya, Hideyuki, Nagano, Osamu

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Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin von Kegelman, Timothy P., Wu, Bainan, Das, Swadesh K., Talukdar, Sarmistha, Beckta, Jason M., Hu, Bin, Emdad, Luni, Valerie, Kristoffer, Sarkar, Devanand, Furnari, Frank B., Cavenee, Webster K., Wei, Jun, Purves, Angela, De, Surya K., Pellecchia, Maurizio, Fisher, Paul B.

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YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity von Yu, Olivia M., Benitez, Jorge A., Plouffe, Steven W., Ryback, Daniel, Klein, Andrea, Smith, Jeff, Greenbaum, Jason, Delatte, Benjamin, Rao, Anjana, Guan, Kun-Liang, Furnari, Frank B., Chaim, Olga Meiri, Miyamoto, Shigeki, Brown, Joan Heller

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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug von Bi, Junfeng, Khan, Atif, Tang, Jun, Armando, Aaron M., Wu, Sihan, Zhang, Wei, Gimple, Ryan C., Reed, Alex, Jing, Hui, Koga, Tomoyuki, Wong, Ivy Tsz-Lo, Gu, Yuchao, Miki, Shunichiro, Yang, Huijun, Prager, Briana, Curtis, Ellis J., Wainwright, Derek A., Furnari, Frank B., Rich, Jeremy N., Cloughesy, Timothy F., Kornblum, Harley I., Quehenberger, Oswald, Rzhetsky, Andrey, Cravatt, Benjamin F., Mischel, Paul S.

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Quantitative Analysis of EGFRvIII Cellular Signaling Networks Reveals a Combinatorial Therapeutic Strategy for Glioblastoma von Huang, Paul H., Mukasa, Akitake, Bonavia, Rudy, Flynn, Ryan A., Brewer, Zachary E., Cavenee, Webster K., Furnari, Frank B., White, Forest M.

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A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma von Read, Renee D, Fenton, Tim R, Gomez, German G, Wykosky, Jill, Vandenberg, Scott R, Babic, Ivan, Iwanami, Akio, Yang, Huijun, Cavenee, Webster K, Mischel, Paul S, Furnari, Frank B, Thomas, John B

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A drosophila model for EGFR-Ras and PI3K-dependent human glioma von Read, Renee D, Cavenee, Webster K, Furnari, Frank B, Thomas, John B

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MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression von Wang, Yemin, Huang, Jen-Wei, Li, Ming, Cavenee, Webster K, Mitchell, Patrick S, Zhou, Xiaofeng, Tewari, Muneesh, Furnari, Frank B, Taniguchi, Toshiyasu

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Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells von Koga, Tomoyuki, Chaim, Isaac A., Benitez, Jorge A., Markmiller, Sebastian, Parisian, Alison D., Hevner, Robert F., Turner, Kristen M., Hessenauer, Florian M., D’Antonio, Matteo, Nguyen, Nam-phuong D., Saberi, Shahram, Ma, Jianhui, Miki, Shunichiro, Boyer, Antonia D., Ravits, John, Frazer, Kelly A., Bafna, Vineet, Chen, Clark C., Mischel, Paul S., Yeo, Gene W., Furnari, Frank B.

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Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion von Chaim, Olga Meiri, Miki, Shunichiro, Prager, Briana C., Ma, Jianhui, Jeong, Anthony Y., Lara, Jacqueline, Tran, Nancy K., Smith, Jeffrey M., Rich, Jeremy N., Gutkind, J. Silvio, Miyamoto, Shigeki, Furnari, Frank B., Brown, Joan Heller

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