Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein–Receptor–Related Protein... von Lai, Keane K.Y, Kweon, Soo-Mi, Chi, Feng, Hwang, Edward, Kabe, Yasuaki, Higashiyama, Reiichi, Qin, Lan, Yan, Rui, Wu, Raymond P, Fujii, Naoaki, French, Samuel, Xu, Jun, Wang, Jian-Ying, Murali, Ramanchadran, Mishra, Lopa, Lee, Ju-Seog, Ntambi, James M, Tsukamoto, Hidekazu

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Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 von Kamadurai, Hari B, Qiu, Yu, Deng, Alan, Harrison, Joseph S, Macdonald, Chris, Actis, Marcelo, Rodrigues, Patrick, Miller, Darcie J, Souphron, Judith, Lewis, Steven M, Kurinov, Igor, Fujii, Naoaki, Hammel, Michal, Piper, Robert, Kuhlman, Brian, Schulman, Brenda A

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A Small Molecule Inhibitor of Monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) Inhibits Repair of Interstrand DNA Cross-link, Enhances DNA Double Strand Break, and Sensi... von Inoue, Akira, Kikuchi, Sotaro, Hishiki, Asami, Shao, Youming, Heath, Richard, Evison, Benjamin J., Actis, Marcelo, Canman, Christine E., Hashimoto, Hiroshi, Fujii, Naoaki

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RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex von Brown, Nicholas G., VanderLinden, Ryan, Watson, Edmond R., Qiao, Renping, Grace, Christy R. R., Yamaguchi, Masaya, Weissmann, Florian, Frye, Jeremiah J., Dube, Prakash, Cho, Shein Ei, Actis, Marcelo L., Rodrigues, Patrick, Fujii, Naoaki, Peters, Jan-Michael, Stark, Holger, Schulman, Brenda A.

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Potential Strategies to Target Protein–Protein Interactions in the DNA Damage Response and Repair Pathways von Fujii, Naoaki

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Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction von Actis, Marcelo L., Ambaye, Nigus D., Evison, Benjamin J., Shao, Youming, Vanarotti, Murugendra, Inoue, Akira, McDonald, Ezelle T., Kikuchi, Sotaro, Heath, Richard, Hara, Kodai, Hashimoto, Hiroshi, Fujii, Naoaki

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Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis von Actis, Marcelo, Inoue, Akira, Evison, Benjamin, Perry, Scott, Punchihewa, Chandanamali, Fujii, Naoaki

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A clickable psoralen to directly quantify DNA interstrand crosslinking and repair von Evison, Benjamin J., Actis, Marcelo L., Fujii, Naoaki

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An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth von LIANG YOU, BIAO HE, MCCORMICK, Frank, JABLONS, David M, ZHIDONG XU, UEMATSU, Kazutsugu, MAZIERES, Julien, FUJII, Naoaki, MIKAMI, Iwao, REGUART, Noemi, MCINTOSH, Joe K, KASHANI-SABET, Mohammed

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Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents von Mahindroo, Neeraj, Punchihewa, Chandanamali, Fujii, Naoaki

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Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway von Mahindroo, Neeraj, Connelly, Michele C., Punchihewa, Chandanamali, Yang, Lei, Yan, Bing, Fujii, Naoaki

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Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains von Mayasundari, Anand, Ferreira, Antonio M., He, Liwen, Mahindroo, Neeraj, Bashford, Don, Fujii, Naoaki

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A phenotypic screen with Trypanosoma brucei for discovering small molecules that target the SLiM‐binding pocket of proliferating cell nuclear antigen orthologs von Actis, Marisa, Fujii, Naoaki, Mackey, Zachary B.

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Efficient formation of 4,6-disubstituted pyrrolo[2,3- d]pyrimidines: a novel route to TWS119, a glycogen synthase kinase-3β inhibitor von Mayasundari, Anand, Fujii, Naoaki

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Asymmetric Intramolecular C-H/Olefin Coupling: Asymmetric Cyclization Reactions of 1,5-Dienes Catalyzed by Rhodium Complexes von Fujii, Naoaki, Kakiuchi, Fumitoshi, Yamada, Airi, Chatani, Naoto, Murai, Shinji

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Transition Metal-Catalyzed Intramolecular Cyclization of 1,5- and 1,6-Dienes via Direct Cleavage and Addition of the Carbon–Hydrogen Bond von Fujii, Naoaki, Kakiuchi, Fumitoshi, Yamada, Airi, Chatani, Naoto, Murai, Shinji

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Identification of Small Molecule Proliferating Cell Nuclear Antigen (PCNA) Inhibitor That Disrupts Interactions with PIP-box Proteins and Inhibits DNA Replication von Punchihewa, Chandanamali, Inoue, Akira, Hishiki, Asami, Fujikawa, Yoshihiro, Connelly, Michele, Evison, Benjamin, Shao, Youming, Heath, Richard, Kuraoka, Isao, Rodrigues, Patrick, Hashimoto, Hiroshi, Kawanishi, Masanobu, Sato, Mamoru, Yagi, Takashi, Fujii, Naoaki

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Evaluation of potency and metabolic stability of diphyllin-derived Vacuolar-ATPase inhibitors von Sanford, Laura M., Keiser, Patrick, Fujii, Naoaki, Woods, Hannah, Zhang, Charlie, Xu, Zhuangyan, Mahajani, Nivedita S., Cortés, Julián González, Plescia, Caroline B., Knipp, Gregory, Stahelin, Robert V., Davey, Robert, Davisson, Vincent Jo

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Power packet dispatching with second-order clock synchronization von Zhou, Yanzi, Takahashi, Ryo, Fujii, Naoaki, Hikihara, Takashi

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Investigating the Replacement of Carboxylates with Carboxamides to Modulate the Safety and Efficacy of Platinum(II) Thioether Cyanide Scavengers von Behymer, Matthew M, Mo, Huaping, Fujii, Naoaki, Suresh, Vallabh, Arzumanian, Ari S, Chan, Adriano, Nath, Anjali K, McCain, Robyn, MacRae, Calum A, Peterson, Randall, Boss, Gerry R, Davisson, Vincent Jo, Knipp, Gregory T

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