Bicyclobutane Carboxylic Amide as a Cysteine-Directed Strained Electrophile for Selective Targeting of Proteins von Tokunaga, Keisuke, Sato, Mami, Kuwata, Keiko, Miura, Chizuru, Fuchida, Hirokazu, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro, Shindo, Naoya, Ojida, Akio

Volltext

Selective and reversible modification of kinase cysteines with chlorofluoroacetamides von Shindo, Naoya, Fuchida, Hirokazu, Sato, Mami, Watari, Kosuke, Shibata, Tomohiro, Kuwata, Keiko, Miura, Chizuru, Okamoto, Kei, Hatsuyama, Yuji, Tokunaga, Keisuke, Sakamoto, Seiichi, Morimoto, Satoshi, Abe, Yoshito, Shiroishi, Mitsunori, Caaveiro, Jose M. M., Ueda, Tadashi, Tamura, Tomonori, Matsunaga, Naoya, Nakao, Takaharu, Koyanagi, Satoru, Ohdo, Shigehiro, Yamaguchi, Yasuchika, Hamachi, Itaru, Ono, Mayumi, Ojida, Akio

Volltext

Intracellular delivery of chemical probes using a glutathione-responsive traceless tag von Aoyama, Eriko, Fuchida, Hirokazu, Oshikawa, Yuji, Uchinomiya, Shohei, Ojida, Akio

Volltext

Optimized Reaction Pair of the CysHis Tag and Ni(II)-NTA Probe for Highly Selective Chemical Labeling of Membrane Proteins von Zenmyo, Naoki, Tokumaru, Hiroki, Uchinomiya, Shohei, Fuchida, Hirokazu, Tabata, Shigekazu, Hamachi, Itaru, Shigemoto, Ryuichi, Ojida, Akio

Volltext

Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation von Kurashige, Nobutaka, Fuchida, Hirokazu, Tabata, Shigekazu, Uchinomiya, Shohei, Ojida, Akio

Volltext

Design of a binuclear Ni(II)-iminodiacetic acid (IDA) complex for selective recognition and covalent labeling of His-tag fused proteins von Takahira, Ikuko, Fuchida, Hirokazu, Tabata, Shigekazu, Shindo, Naoya, Uchinomiya, Shohei, Hamachi, Itaru, Ojida, Akio

Volltext

Covalent drug approach for targeting the undruggable proteome von Fuchida, Hirokazu

Volltext

Electron Microscopic Detection of Single Membrane Proteins by a Specific Chemical Labeling von Tabata, Shigekazu, Jevtic, Marijo, Kurashige, Nobutaka, Fuchida, Hirokazu, Kido, Munetsugu, Tani, Kazushi, Zenmyo, Naoki, Uchinomiya, Shohei, Harada, Harumi, Itakura, Makoto, Hamachi, Itaru, Shigemoto, Ryuichi, Ojida, Akio

Volltext

Covalent drug approach for targeting the undruggable proteome von Fuchida, Hirokazu

Volltext

Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines von Sato, Mami, Fuchida, Hirokazu, Shindo, Naoya, Kuwata, Keiko, Tokunaga, Keisuke, Xiao-Lin, Guo, Inamori, Ryo, Hosokawa, Keitaro, Watari, Kosuke, Shibata, Tomohiro, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro, Ono, Mayumi, Ojida, Akio

Volltext

Design of Coordination Interaction of Zn(II) Complex with Oligo-Aspartate Peptide to Afford a High-Affinity Tag–Probe Pair von Fuchida, Hirokazu, Tabata, Shigekazu, Shindo, Naoya, Takashima, Ippei, Leng, Qiao, Hatsuyama, Yuji, Hamachi, Itaru, Ojida, Akio

Volltext

コバレントドラッグ創薬によるアンドラッガブル標的の攻略 von 渕田, 大和

Volltext

7H-PYRROLO[2,3-D]PYRIMIDINE-4-AMINE DERIVATIVE von MIZUTANI, TAKASHI, YAMAMOTO, FUYUKI, KASUGA, HIDEFUMI, OGINO, YOSHIO, KOBAYAKAWA, YU, HARA, SHOKI, FUCHIDA, HIROKAZU

Volltext bestellen

Substituted pyrrolo[2,3-d]pyrimidines as EGFR inhibitors von Mizutani, Takashi, Fuchida, Hirokazu, Yamamoto, Fuyuki, Kasuga, Hidefumi, Kobayakawa, Yu, Ogino, Yoshio, Hara, Shoki

Volltext bestellen

7H-PYRROLO[2,3-D]PYRIMIDINE-4-AMINE DERIVATIVE von YAMAMOTO Fuyuki, KOBAYAKAWA Yu, HARA Shoki, FUCHIDA Hirokazu, KASUGA Hidefumi, MIZUTANI Takashi, OGINO Yoshio

Volltext bestellen

7H-pyrrolo(2,3-d)pyrimidine-4-amine derivative von OGINO, Yoshio, KASUGA, Hidefumi, FUCHIDA, Hirokazu, YAMAMOTO, Fuyuki, HARA, Shoki, MIZUTANI, Takashi, KOBAYAKAWA, Yu

Volltext bestellen

7H-PYRROLO[2,3-D]PYRIMIDINE-4-AMINE DERIVATIVE von OGINO, Yoshio, KASUGA, Hidefumi, FUCHIDA, Hirokazu, YAMAMOTO, Fuyuki, HARA, Shoki, MIZUTANI, Takashi, KOBAYAKAWA, Yu

Volltext bestellen

7H-PYRROLO[2,3-D]PYRIMIDINE-4-AMINE DERIVATIVE von YAMAMOTO Fuyuki, KOBAYAKAWA Yu, HARA Shoki, FUCHIDA Hirokazu, KASUGA Hidefumi, MIZUTANI Takashi, OGINO Yoshio

Volltext bestellen

DÉRIVÉ DE 7H-PYRROLO [2,3-D] PYRIMIDINE-4-AMINE von YAMAMOTO Fuyuki, KOBAYAKAWA Yu, HARA Shoki, FUCHIDA Hirokazu, KASUGA Hidefumi, MIZUTANI Takashi, OGINO Yoshio

Volltext bestellen

7H-PYRROLO[2,3-D]PYRIMIDINE-4-AMINE DERIVATIVE von YAMAMOTO Fuyuki, KOBAYAKAWA Yu, HARA Shoki, FUCHIDA Hirokazu, KASUGA Hidefumi, MIZUTANI Takashi, OGINO Yoshio

Volltext bestellen