New ‘chemical probes’ to examine the role of the hFPRL1 (or ALXR) receptor in inflammation von Frohn, Mike, Xu, Han, Zou, Xiaoming, Chang, Catherine, McElvaine, Michele, Plant, Matthew H., Wong, Min, Tagari, Philip, Hungate, Randall, Bürli, Roland W.

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A Soluble Base for the Copper-Catalyzed Imidazole N-Arylations with Aryl Halides von Liu, Longbin, Frohn, Mike, Xi, Ning, Dominguez, Celia, Hungate, Randy, Reider, Paul J

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Impact of Glycation on Antibody Clearance von Yang, Jane, Primack, Ronya, Frohn, Mike, Wang, Wei, Luan, Peng, Retter, Marc W., Flynn, Gregory C.

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N-substituted azaindoles as potent inhibitors of Cdc7 kinase von Bryan, Marian C., Falsey, James R., Frohn, Mike, Reichelt, Andreas, Yao, Guomin, Bartberger, Michael D., Bailis, Julie M., Zalameda, Leeanne, Miguel, Tisha San, Doherty, Elizabeth M., Allen, John G.

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Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents von Bürli, Roland W., Xu, Han, Zou, Xiaoming, Muller, Kristine, Golden, Jennifer, Frohn, Mike, Adlam, Matthew, Plant, Matthew H., Wong, Min, McElvain, Michele, Regal, Kelly, Viswanadhan, Vellarkad N., Tagari, Philip, Hungate, Randall

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Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5 von Cee, Victor J, Frohn, Mike, Lanman, Brian A, Golden, Jennifer, Muller, Kristine, Neira, Susana, Pickrell, Alex, Arnett, Heather, Buys, Janet, Gore, Anu, Fiorino, Mike, Horner, Michelle, Itano, Andrea, Lee, Matt R, McElvain, Michele, Middleton, Scot, Schrag, Michael, Rivenzon-Segal, Dalia, Vargas, Hugo M, Xu, Han, Xu, Yang, Zhang, Xuxia, Siu, Jerry, Wong, Min, Bürli, Roland W

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Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1α prolyl hydroxylase-2 inhibitors von Frohn, Mike, Viswanadhan, Vellarkad, Pickrell, Alexander J., Golden, Jennifer E., Muller, Kristine M., Bürli, Roland W., Biddlecome, Gloria, Yoder, Sean C., Rogers, Norma, Dao, Jennifer H., Hungate, Randall, Allen, Jennifer R.

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An efficient synthesis of 1,6- and 1,7-dibromo-3-aminoisoquinolines: versatile templates for the preparation of functionalized isoquinolines von Frohn, Mike, Bürli, Roland W., Riahi, Bobby, Hungate, Randall W.

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Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups von Reed, Anthony B., Lanman, Brian A., Neira, Susana, Harrington, Paul E., Sham, Kelvin K.C., Frohn, Mike, Pickrell, Alexander J., Tasker, Andrew S., Gore, Anu, Fiorino, Mike, Itano, Andrea, McElvain, Michele, Middleton, Scot, Morrison, Henry, Xu, Han, Xu, Yang, Wong, Min, Cee, Victor J.

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Novel 5- and 6-subtituted benzothiazoles with improved physicochemical properties: Potent S1P1 agonists with in vivo lymphocyte-depleting activity von Frohn, Mike, Cee, Victor J., Lanman, Brian A., Pickrell, Alexander J., Golden, Jennifer, Rivenzon-Segal, Dalia, Middleton, Scot, Fiorino, Mike, Xu, Han, Schrag, Michael, Xu, Yang, McElvain, Michele, Muller, Kristine, Siu, Jerry, Bürli, Roland

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Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core von Harrington, Paul E, Croghan, Michael D, Fotsch, Christopher, Frohn, Mike, Lanman, Brian A, Pennington, Lewis D, Pickrell, Alexander J, Reed, Anthony B, Sham, Kelvin K. C, Tasker, Andrew, Arnett, Heather A, Fiorino, Michael, Lee, Matthew R, McElvain, Michele, Morrison, Henry G, Xu, Han, Xu, Yang, Zhang, Xuxia, Wong, Min, Cee, Victor J

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Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1) von Lanman, Brian A, Cee, Victor J, Cheruku, Srinivasa R, Frohn, Mike, Golden, Jennifer, Lin, Jian, Lobera, Mercedes, Marantz, Yael, Muller, Kristine M, Neira, Susana C, Pickrell, Alexander J, Rivenzon-Segal, Dalia, Schutz, Nili, Sharadendu, Anurag, Yu, Xiang, Zhang, Zhaoda, Buys, Janet, Fiorino, Mike, Gore, Anu, Horner, Michelle, Itano, Andrea, McElvain, Michele, Middleton, Scot, Schrag, Michael, Vargas, Hugo M, Xu, Han, Xu, Yang, Zhang, Xuxia, Siu, Jerry, Bürli, Roland W

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Optimization of a Potent, Orally Active S1P 1 Agonist Containing a Quinolinone Core von Harrington, Paul E., Croghan, Michael D., Fotsch, Christopher, Frohn, Mike, Lanman, Brian A., Pennington, Lewis D., Pickrell, Alexander J., Reed, Anthony B., Sham, Kelvin K. C., Tasker, Andrew, Arnett, Heather A., Fiorino, Michael, Lee, Matthew R., McElvain, Michele, Morrison, Henry G., Xu, Han, Xu, Yang, Zhang, Xuxia, Wong, Min, Cee, Victor J.

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Discovery of AMG 369, a Thiazolo[5,4- b ]pyridine Agonist of S1P 1 and S1P 5 von Cee, Victor J., Frohn, Mike, Lanman, Brian A., Golden, Jennifer, Muller, Kristine, Neira, Susana, Pickrell, Alex, Arnett, Heather, Buys, Janet, Gore, Anu, Fiorino, Mike, Horner, Michelle, Itano, Andrea, Lee, Matt R., McElvain, Michele, Middleton, Scot, Schrag, Michael, Rivenzon-Segal, Dalia, Vargas, Hugo M., Xu, Han, Xu, Yang, Zhang, Xuxia, Siu, Jerry, Wong, Min, Bürli, Roland W.

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Discovery of a Potent, S1P 3 -Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P 1 ) von Lanman, Brian A., Cee, Victor J., Cheruku, Srinivasa R., Frohn, Mike, Golden, Jennifer, Lin, Jian, Lobera, Mercedes, Marantz, Yael, Muller, Kristine M., Neira, Susana C., Pickrell, Alexander J., Rivenzon-Segal, Dalia, Schutz, Nili, Sharadendu, Anurag, Yu, Xiang, Zhang, Zhaoda, Buys, Janet, Fiorino, Mike, Gore, Anu, Horner, Michelle, Itano, Andrea, McElvain, Michele, Middleton, Scot, Schrag, Michael, Vargas, Hugo M., Xu, Han, Xu, Yang, Zhang, Xuxia, Siu, Jerry, Bürli, Roland W.

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Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1alpha prolyl hydroxylase-2 inhibitors von Frohn, Mike, Viswanadhan, Vellarkad, Pickrell, Alexander J, Golden, Jennifer E, Muller, Kristine M, Bürli, Roland W, Biddlecome, Gloria, Yoder, Sean C, Rogers, Norma, Dao, Jennifer H, Hungate, Randall, Allen, Jennifer R

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derivados de piridina e pirimidina como inibidores de fosfodiesterase 10 von MATTEW R. KALLER, TOM NGUYEN, KAUSTAV BISWAS, JENNIFER R.ALLEN, FRENEL FILS DEMORIN, ALEX PICKRELL, ESSA HU, KELVIN SHAM, FRANK CHAVEZ JUNIOR, JAMES R.FALSEY, SHANNON RUMFELT, ROXANNE KUNZ, NING CHEN, ROB RZASA, GUOMIN YAO, ANDREAS REICHELT, PAUL HARRINGTON, DANIEL B. HORNE, HOLGER MONENSCHEIN, MIKE FROHN

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A Soluble Base for the Copper-Catalyzed Imidazole N-Arylations with Aryl Halides von Liu, Longbin, Frohn, Mike, Xi, Ning, Dominguez, Celia, Hungate, Randy, Reider, Paul J.

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PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS von RUMFELT, SHANNON, SHAM, KELVIN, CHEN, NING, DEMORIN, FRENEL FILS, ALLEN, JENNIFER R, KALLER, MATTHEW R, MONENSCHEIN, HOLGER, RZASA, ROB, BISWAS, KAUSTAV, CHAVEZ, FRANK, JR, YAO, GUOMIN, HARRINGTON, PAUL E, FROHN, MIKE, HORNE, DANIEL B, KUNZ, ROXANNE, REICHELT, ANDREAS, FALSEY, JAMES R, PICKRELL, ALEX, HU, ESSA, NGUYEN, TOM

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Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors von RUMFELT, SHANNON, SHAM, KELVIN, CHEN, NING, DEMORIN, FRENEL FILS, ALLEN, JENNIFER R, HARRINGTON, PAUL, KALLER, MATTHEW R, MONENSCHEIN, HOLGER, RZASA, ROB, BISWAS, KAUSTAV, CHAVEZ, FRANK, JR, HORNE, DAN, YAO, GUOMIN, FROHN, MIKE, KUNZ, ROXANNE, REICHELT, ANDREAS, FALSEY, JAMES R, PICKRELL, ALEX, HU, ESSA, NGUYEN, TOM

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