Molecular targets for 17α-ethynyl-5-androstene-3β,7β,17β-triol, an anti-inflammatory agent derived from the human metabolome von Reading, Christopher L, Frincke, James M, White, Steven K

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An Orally Bioavailable Synthetic Analog of an Active Dehydroepiandrosterone Metabolite Reduces Established Disease in Rodent Models of Rheumatoid Arthritis von Offner, Halina, Firestein, Gary S, Boyle, David L, Pieters, Raymond, Frincke, James M, Garsd, Armando, White, Steven K, Reading, Christopher L, Auci, Dominick L

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An Anti-Inflammatory Sterol Decreases Obesity-Related Inflammation-Induced Insulin Resistance and Metabolic Dysregulation von Reading, Chris L., Flores-Riveros, Jaime, Stickney, Dwight R., Frincke, James M.

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5-Androstene-3β,7β,17β-triol (β-AET) slows thermal injury induced osteopenia in mice: relation to aging and osteoporosis von Malik, Ajay K, Khaldoyanidi, Sophia, Auci, Dominick L, Miller, Scott C, Ahlem, Clarence N, Reading, Christopher L, Page, Theodore, Frincke, James M

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Safety and Activity of the Immune Modulator HE2000 on the Incidence of Tuberculosis and Other Opportunistic Infections in AIDS Patients von STICKNEY, Dwight R, NOVELJIC, Zoja, GARSD, Armando, DESTICHE, Daniel A, FRINCKE, James M

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A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats von Lu, Min, Patsouris, David, Li, Pingping, Flores-Riveros, Jaime, Frincke, James M, Watkins, Steve, Schenk, Simon, Olefsky, Jerrold M

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HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression von Conrad, Douglas, Wang, Angela, Pieters, Raymond, Nicoletti, Ferdinando, Mangano, Katia, van Heeckeren, Anna M, White, Steven K, Frincke, James M, Reading, Christopher L, Stickney, Dwight, Auci, Dominick L

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7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases von Auci, Dominick L, Reading, Christopher L, Frincke, James M

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5-androstenediol improves survival in clinically unsupported rhesus monkeys with radiation-induced myelosuppression von Stickney, Dwight R., Dowding, Charles, Authier, Simon, Garsd, Armando, Onizuka-Handa, Nanette, Reading, Christopher, Frincke, James M.

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5-Androstenediol Ameliorates Pleurisy, Septic Shock, and Experimental Autoimmune Encephalomyelitis in Mice von Nicoletti, Ferdinando, Auci, Dominick L., Mangano, Katia, Flores-Riveros, Jaime, Villegas, Sonia, Frincke, James M., Reading, Christopher L., Offner, Halina

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A synthetic anti‐inflammatory sterol improves insulin sensitivity in insulin‐resistant obese impaired glucose tolerance subjects von Reading, Christopher L., Stickney, Dwight R., Flores‐Riveros, Jaime, Destiche, Daniel A., Ahlem, Clarence N., Cefalu, William T., Frincke, James M.

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Amelioration of glucose intolerance by the synthetic androstene HE3286: link to inflammatory pathways von Wang, Tianlun, Villegas, Sonia, Huang, Yujin, White, Steve K, Ahlem, Clarence, Lu, Min, Olefsky, Jerrold M, Reading, Chris, Frincke, James M, Alleva, David, Flores-Riveros, Jaime

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17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease von Auci, Dominick L., Reading, Christopher L., Ahlem, Clarence N., Fagone, Paolo, Philippens, Ingrid, Nicoletti, Ferdinando, Frincke, James M.

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5-Androstene-3 beta ,7 beta ,17 beta -triol ( beta -AET) Slows Thermal Injury Induced Osteopenia in Mice: Relation to Aging and Osteoporosis von Malik, Ajay K, Khaldoyanidi, Sophia, Auci, Dominick L, Miller, Scott C, Ahlem, Clarence N, Reading, Christopher L, Page, Theodore, Frincke, James M

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A Potential Role for 5-Androstene-3β,7β,17β-triol in Obesity and Metabolic Syndrome von Auci, Dominick L., Ahlem, Clarence N., Kennedy, Michael R., Page, Theodore M., Reading, Christopher L., Frincke, James M.

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Novel components of the human metabolome: The identification, characterization and anti-inflammatory activity of two 5-androstene tetrols von Ahlem, Clarence N., Page, Theodore M., Auci, Dominick L., Kennedy, Michael R., Mangano, Katia, Nicoletti, Ferdinando, Ge, Yu, Huang, Yujin, White, Steven K., Villegas, Sonia, Conrad, Douglas, Wang, Angela, Reading, Christopher L., Frincke, James M.

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Differential metabolism of androst-5-ene-3β,17β-diol between rats, canines, monkeys and humans von Ahlem, Clarence N., White, Steven K., Page, Theodore M., Frincke, James M.

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HE3286, an orally bioavailable synthetic analogue of an active DHEA metabolite suppresses spontaneous autoimmune diabetes in the non-obese diabetic (NOD) mouse von Kosiewicz, Michele M., Auci, Dominick L., Fagone, Paolo, Mangano, Katia, Caponnetto, Salvatore, Tucker, Colleen F., Azeem, Nabeel, White, Steven K., Frincke, James M., Reading, Christopher L., Nicoletti, Ferdinando

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Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome von Ahlem, Clarence N., Auci, Dominick L., Nicoletti, Ferdinando, Pieters, Raymond, Kennedy, Michael R., Page, Theodore M., Reading, Christopher L., Enioutina, Elena Y., Frincke, James M.

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Pharmacology and immune modulating properties of 5-androstene-3 beta ,7 beta ,17 beta -triol, a DHEA metabolite in the human metabolome von Ahlem, Clarence N, Auci, Dominick L, Nicoletti, Ferdinando, Pieters, Raymond, Kennedy, Michael R, Page, Theodore M, Reading, Christopher L, Enioutina, Elena Y, Frincke, James M

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