Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models von French, Dorothy M, Lin, Benjamin C, Wang, Manping, Adams, Camellia, Shek, Theresa, Hötzel, Kathy, Bolon, Brad, Ferrando, Ronald, Blackmore, Craig, Schroeder, Kurt, Rodriguez, Luis A, Hristopoulos, Maria, Venook, Rayna, Ashkenazi, Avi, Desnoyers, Luc R

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Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening von Sawey, Eric T., Chanrion, Maia, Cai, Chunlin, Wu, Guanming, Zhang, Jianping, Zender, Lars, Zhao, Alice, Busuttil, Ronald W., Yee, Herman, Stein, Lincoln, French, Dorothy M., Finn, Richard S., Lowe, Scott W., Powers, Scott

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Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis von Newton, Kim, Dugger, Debra L., Wickliffe, Katherine E., Kapoor, Neeraj, de Almagro, M. Cristina, Vucic, Domagoj, Komuves, Laszlo, Ferrando, Ronald E., French, Dorothy M., Webster, Joshua, Roose-Girma, Merone, Warming, Søren, Dixit, Vishva M.

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USP1 Deubiquitinates ID Proteins to Preserve a Mesenchymal Stem Cell Program in Osteosarcoma von Williams, Samuel A., Maecker, Heather L., French, Dorothy M., Liu, Jinfeng, Gregg, Andrew, Silverstein, Leah B., Cao, Tim C., Carano, Richard A.D., Dixit, Vishva M.

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FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways von Wu, Ai-Luen, Coulter, Sally, Liddle, Christopher, Wong, Anne, Eastham-Anderson, Jeffrey, French, Dorothy M, Peterson, Andrew S, Sonoda, Junichiro

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Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation von Dey, Anwesha, Seshasayee, Dhaya, Noubade, Rajkumar, French, Dorothy M., Liu, Jinfeng, Chaurushiya, Mira S., Kirkpatrick, Donald S., Pham, Victoria C., Lill, Jennie R., Bakalarski, Corey E., Wu, Jiansheng, Phu, Lilian, Katavolos, Paula, LaFave, Lindsay M., Abdel-Wahab, Omar, Modrusan, Zora, Seshagiri, Somasekar, Dong, Ken, Lin, Zhonghua, Balazs, Mercedesz, Suriben, Rowena, Newton, Kim, Hymowitz, Sarah, Garcia-Manero, Guillermo, Martin, Flavius, Levine, Ross L., Dixit, Vishva M.

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Diverse modes of genomic alteration in hepatocellular carcinoma von Jhunjhunwala, Suchit, Jiang, Zhaoshi, Stawiski, Eric W, Gnad, Florian, Liu, Jinfeng, Mayba, Oleg, Du, Pan, Diao, Jingyu, Johnson, Stephanie, Wong, Kwong-Fai, Gao, Zhibo, Li, Yingrui, Wu, Thomas D, Kapadia, Sharookh B, Modrusan, Zora, French, Dorothy M, Luk, John M, Seshagiri, Somasekar, Zhang, Zemin

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Differential effects of targeting Notch receptors in a mouse model of liver cancer von Huntzicker, Erik G., Hötzel, Kathy, Choy, Lisa, Che, Li, Ross, Jed, Pau, Gregoire, Sharma, Neeraj, Siebel, Christian W., Chen, Xin, French, Dorothy M.

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TSPAN12 Regulates Retinal Vascular Development by Promoting Norrin- but Not Wnt-Induced FZD4/β-Catenin Signaling von Junge, Harald J., Yang, Stacey, Burton, Jeremy B., Paes, Kim, Shu, Xiao, French, Dorothy M., Costa, Mike, Rice, Dennis S., Ye, Weilan

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Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival von Schwickart, Martin, Dornan, David, Huang, David C. S, Liu, Jinfeng, Lill, Jennie R, Maecker, Heather, Bazan, Fernando, Huang, XiaoDong, Yue, Peng, French, Dorothy M, Eastham-Anderson, Jeffrey, Dixit, Vishva M, Ferrando, Ronald, O'Rourke, Karen

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Anti-HBV response to toll-like receptor 7 agonist GS-9620 is associated with intrahepatic aggregates of T cells and B cells von Li, Li, Barry, Vivian, Daffis, Stephane, Niu, Congrong, Huntzicker, Erik, French, Dorothy M., Mikaelian, Igor, Lanford, Robert E., Delaney, William E., Fletcher, Simon P.

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf von Dixit, Vishva M, Mariathasan, Sanjeev, Newton, Kim, Monack, Denise M, Vucic, Domagoj, French, Dorothy M, Lee, Wyne P, Roose-Girma, Meron, Erickson, Sharon

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease von Liles, John T, Corkey, Britton K, Notte, Gregory T, Budas, Grant R, Lansdon, Eric B, Hinojosa-Kirschenbaum, Ford, Badal, Shawn S, Lee, Michael, Schultz, Brian E, Wise, Sarah, Pendem, Swetha, Graupe, Michael, Castonguay, Laurie, Koch, Keith A, Wong, Melanie H, Papalia, Giuseppe A, French, Dorothy M, Sullivan, Theodore, Huntzicker, Erik G, Ma, Frank Y, Nikolic-Paterson, David J, Altuhaifi, Tareq, Yang, Haichun, Fogo, Agnes B, Breckenridge, David G

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Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival von Holst, Charles R, Bou-Reslan, Hani, Gore, Bryan B, Wong, Karen, Grant, Deanna, Chalasani, Sreedevi, Carano, Richard A, Frantz, Gretchen D, Tessier-Lavigne, Marc, Bolon, Brad, French, Dorothy M, Ashkenazi, Avi

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Delta‐Like Protein 3 Expression and Targeting in Merkel Cell Carcinoma von Xie, Hao, Kaye, Frederic J., Isse, Kumiko, Sun, Yan, Ramoth, Johanna, French, Dorothy M., Flotte, Thomas J., Luo, Yan, Saunders, Laura R., Mansfield, Aaron S.

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Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies von Newton, Kim, Matsumoto, Marissa L., Wertz, Ingrid E., Kirkpatrick, Donald S., Lill, Jennie R., Tan, Jenille, Dugger, Debra, Gordon, Nathaniel, Sidhu, Sachdev S., Fellouse, Frederic A., Komuves, Laszlo, French, Dorothy M., Ferrando, Ronald E., Lam, Cynthia, Compaan, Deanne, Yu, Christine, Bosanac, Ivan, Hymowitz, Sarah G., Kelley, Robert F., Dixit, Vishva M.

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Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating β-Catenin Signaling von PAI, Rama, DUNLAP, Debra, JING QING, MOHTASHEMI, Iman, HOTZEL, Kathy, FRENCH, Dorothy M

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FGFR3 Stimulates Stearoyl CoA Desaturase 1 Activity to Promote Bladder Tumor Growth von XIANGNAN DU, WANG, Qian-Rena, CHAN, Emily, MERCHANT, Mark, JINFENG LIU, FRENCH, Dorothy, ASHKENAZI, Avi, JING QING

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COP1 is a tumour suppressor that causes degradation of ETS transcription factors von Vitari, Alberto C., Leong, Kevin G., Newton, Kim, Yee, Cindy, O’Rourke, Karen, Liu, Jinfeng, Phu, Lilian, Vij, Rajesh, Ferrando, Ronald, Couto, Suzana S., Mohan, Sankar, Pandita, Ajay, Hongo, Jo-Anne, Arnott, David, Wertz, Ingrid E., Gao, Wei-Qiang, French, Dorothy M., Dixit, Vishva M.

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A Rare Population of CD24+ITGB4+Notchhi Cells Drives Tumor Propagation in NSCLC and Requires Notch3 for Self-Renewal von Zheng, Yanyan, de la Cruz, Cecile C., Sayles, Leanne C., Alleyne-Chin, Chris, Vaka, Dedeepya, Knaak, Tim D., Bigos, Marty, Xu, Yue, Hoang, Chuong D., Shrager, Joseph B., Fehling, Hans Joerg, French, Dorothy, Forrest, William, Jiang, Zhaoshi, Carano, Richard A.D., Barck, Kai H., Jackson, Erica L., Sweet-Cordero, E. Alejandro

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