Structural elements in the flexible tail of the co-chaperone p23 coordinate client binding and progression of the Hsp90 chaperone cycle von Biebl, Maximilian M., Lopez, Abraham, Rehn, Alexandra, Freiburger, Lee, Lawatscheck, Jannis, Blank, Birgit, Sattler, Michael, Buchner, Johannes

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Modulation of the Hsp90 Chaperone Cycle by a Stringent Client Protein von Lorenz, Oliver Robin, Freiburger, Lee, Rutz, Daniel Andreas, Krause, Maike, Zierer, Bettina Karolina, Alvira, Sara, Cuéllar, Jorge, Valpuesta, José María, Madl, Tobias, Sattler, Michael, Buchner, Johannes

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A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease von Riebold, Mathias, Kozany, Christian, Freiburger, Lee, Sattler, Michael, Buchfelder, Michael, Hausch, Felix, Stalla, Günter K, Paez-Pereda, Marcelo

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A switch point in the molecular chaperone Hsp90 responding to client interaction von Rutz, Daniel Andreas, Luo, Qi, Freiburger, Lee, Madl, Tobias, Kaila, Ville R. I., Sattler, Michael, Buchner, Johannes

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Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme von Mittermaier, Anthony K, Freiburger, Lee A, Baettig, Oliver M, Sprules, Tara, Berghuis, Albert M, Auclair, Karine

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A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer von Colaluca, Ivan Nicola, Basile, Andrea, Freiburger, Lee, D'Uva, Veronica, Disalvatore, Davide, Vecchi, Manuela, Confalonieri, Stefano, Tosoni, Daniela, Cecatiello, Valentina, Malabarba, Maria Grazia, Yang, Chun-Jiun, Kainosho, Masatsune, Sattler, Michael, Mapelli, Marina, Pece, Salvatore, Di Fiore, Pier Paolo

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Elucidating Protein Binding Mechanisms by Variable-c ITC von Freiburger, Lee A, Auclair, Karine, Mittermaier, Anthony K

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Van ‘t Hoff global analyses of variable temperature isothermal titration calorimetry data von Freiburger, Lee A., Auclair, Karine, Mittermaier, Anthony K.

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Artificial Accelerators of the Molecular Chaperone Hsp90 Facilitate Rate-Limiting Conformational Transitions von Zierer, Bettina K., Weiwad, Matthias, Rübbelke, Martin, Freiburger, Lee, Fischer, Gunter, Lorenz, Oliver R., Sattler, Michael, Richter, Klaus, Buchner, Johannes

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Van't Hoff global analyses of variable temperature isothermal titration calorimetry data von Freiburger, Lee A, Auclair, Karine, Mittermaier, Anthony K

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Global ITC fitting methods in studies of protein allostery von Freiburger, Lee, Auclair, Karine, Mittermaier, Anthony

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Efficient segmental isotope labeling of multi-domain proteins using Sortase A von Freiburger, Lee, Sonntag, Miriam, Hennig, Janosch, Li, Jian, Zou, Peijian, Sattler, Michael

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Collecting variable-concentration isothermal titration calorimetry datasets in order to determine binding mechanisms von Freiburger, Lee A, Mittermaier, Anthony K, Auclair, Karine

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Client binding shifts the populations of dynamic Hsp90 conformations through an allosteric network von Lopez, Abraham, Dahiya, Vinay, Delhommel, Florent, Freiburger, Lee, Stehle, Ralf, Asami, Sam, Rutz, Daniel, Blair, Laura, Buchner, Johannes, Sattler, Michael

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Substrate-dependent switching of the allosteric binding mechanism of a dimeric enzyme von Freiburger, Lee, Miletti, Teresa, Zhu, Siqi, Baettig, Oliver, Berghuis, Albert, Auclair, Karine, Mittermaier, Anthony

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Abstract 1737: Understanding the geometry and valency of bispecific antibodies in the optimization of tumor-dependent activation of 4-1BB von von Rossum, Anna, Pratap, Harsh, Newhook, Lisa, Halvorsen, Elizabeth C., Freiburger, Lee, Duan, Renee, Stevens, Charles, Tcaciuc, Dimitri, Volkers, Gesa, Browman, Duncan, Clavette, Brandon, Mills, David, Spreter, Thomas, Patton, Daniel T.

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Hsp90·Cdc37 Complexes with Protein Kinases Form Cooperatively with Multiple Distinct Interaction Sites von Eckl, Julia M., Scherr, Matthias J., Freiburger, Lee, Daake, Marina A., Sattler, Michael, Richter, Klaus

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Kinetic and Structural Analysis of Bisubstrate Inhibition of the Salmonella enterica Aminoglycoside 6‘-N-Acetyltransferase von Magalhães, Maria L. B, Vetting, Matthew W, Gao, Feng, Freiburger, Lee, Auclair, Karine, Blanchard, John S

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Collecting Variable-concentration Isothermal Titration Calorimetry Datasets in Order to Determine Binding Mechanisms von Freiburger, Lee A., Mittermaier, Anthony K., Auclair, Karine

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Aktivatoren des molekularen Chaperons Hsp90 erleichtern geschwindigkeitsbestimmende Konformationsänderungen von Zierer, Bettina K., Weiwad, Matthias, Rübbelke, Martin, Freiburger, Lee, Fischer, Gunter, Lorenz, Oliver R., Sattler, Michael, Richter, Klaus, Buchner, Johannes

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