Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol von Liu, Su-Yang, Aliyari, Roghiyh, Chikere, Kelechi, Li, Guangming, Marsden, Matthew D., Smith, Jennifer K., Pernet, Olivier, Guo, Haitao, Nusbaum, Rebecca, Zack, Jerome A., Freiberg, Alexander N., Su, Lishan, Lee, Benhur, Cheng, Genhong

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Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis von Johnson, Bryan A., Xie, Xuping, Bailey, Adam L., Kalveram, Birte, Lokugamage, Kumari G., Muruato, Antonio, Zou, Jing, Zhang, Xianwen, Juelich, Terry, Smith, Jennifer K., Zhang, Lihong, Bopp, Nathen, Schindewolf, Craig, Vu, Michelle, Vanderheiden, Abigail, Winkler, Emma S., Swetnam, Daniele, Plante, Jessica A., Aguilar, Patricia, Plante, Kenneth S., Popov, Vsevolod, Lee, Benhur, Weaver, Scott C., Suthar, Mehul S., Routh, Andrew L., Ren, Ping, Ku, Zhiqiang, An, Zhiqiang, Debbink, Kari, Diamond, Michael S., Shi, Pei-Yong, Freiberg, Alexander N., Menachery, Vineet D.

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SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species von Moustaqil, Mehdi, Ollivier, Emma, Chiu, Hsin-Ping, Van Tol, Sarah, Rudolffi-Soto, Paulina, Stevens, Christian, Bhumkar, Akshay, Hunter, Dominic J. B., Freiberg, Alexander N., Jacques, David, Lee, Benhur, Sierecki, Emma, Gambin, Yann

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Favipiravir (T-705) protects against Nipah virus infection in the hamster model von Dawes, Brian E., Kalveram, Birte, Ikegami, Tetsuro, Juelich, Terry, Smith, Jennifer K., Zhang, Lihong, Park, Arnold, Lee, Benhur, Komeno, Takashi, Furuta, Yousuke, Freiberg, Alexander N.

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Henipavirus infection of the central nervous system von Dawes, Brian E, Freiberg, Alexander N

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The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response von Bharaj, Preeti, Wang, Yao E, Dawes, Brian E, Yun, Tatyana E, Park, Arnold, Yen, Benjamin, Basler, Christopher F, Freiberg, Alexander N, Lee, Benhur, Rajsbaum, Ricardo

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ISG15 deficiency and increased viral resistance in humans but not mice von Speer, Scott D., Li, Zhi, Buta, Sofija, Payelle-Brogard, Béatrice, Qian, Li, Vigant, Frederic, Rubino, Erminia, Gardner, Thomas J., Wedeking, Tim, Hermann, Mark, Duehr, James, Sanal, Ozden, Tezcan, Ilhan, Mansouri, Nahal, Tabarsi, Payam, Mansouri, Davood, Francois-Newton, Véronique, Daussy, Coralie F., Rodriguez, Marisela R., Lenschow, Deborah J., Freiberg, Alexander N., Tortorella, Domenico, Piehler, Jacob, Lee, Benhur, García-Sastre, Adolfo, Pellegrini, Sandra, Bogunovic, Dusan

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Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity von Johnson, Bryan A, Hage, Adam, Kalveram, Birte, Mears, Megan, Plante, Jessica A, Rodriguez, Sergio E, Ding, Zhixia, Luo, Xuemei, Bente, Dennis, Bradrick, Shelton S, Freiberg, Alexander N, Popov, Vsevolod, Rajsbaum, Ricardo, Rossi, Shannan, Russell, William K, Menachery, Vineet D

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Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway von Park, Arnold, Yun, Tatyana, Vigant, Frederic, Pernet, Olivier, Won, Sohui T, Dawes, Brian E, Bartkowski, Wojciech, Freiberg, Alexander N, Lee, Benhur

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Pteropus vampyrus TRIM40 Is an Interferon-Stimulated Gene That Antagonizes RIG-I-like Receptors von van Tol, Sarah, Hage, Adam, Rajsbaum, Ricardo, Freiberg, Alexander N

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Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication von Rodríguez-Salazar, Carlos A, van Tol, Sarah, Mailhot, Olivier, Gonzalez-Orozco, Maria, Galdino, Gabriel T, Warren, Abbey N, Teruel, Natalia, Behera, Padmanava, Afreen, Kazi Sabrina, Zhang, Lihong, Juelich, Terry L, Smith, Jennifer K, Zylber, María Inés, Freiberg, Alexander N, Najmanovich, Rafael J, Giraldo, Maria I, Rajsbaum, Ricardo

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Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing von Ochoa, Lorenzo F., Kholodnykh, Alexander, Villarreal, Paula, Tian, Bing, Pal, Rahul, Freiberg, Alexander N., Brasier, Allan R., Motamedi, Massoud, Vargas, Gracie

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The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains von Lubaki, Ndongala M, Ilinykh, Philipp, Pietzsch, Colette, Tigabu, Bersabeh, Freiberg, Alexander N, Koup, Richard A, Bukreyev, Alexander

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Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding von Wang, Yao E, Park, Arnold, Lake, Michael, Pentecost, Mickey, Torres, Betsabe, Yun, Tatyana E, Wolf, Mike C, Holbrook, Michael R, Freiberg, Alexander N, Lee, Benhur

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Role of Protein Phosphatase 1 in Dephosphorylation of Ebola Virus VP30 Protein and Its Targeting for the Inhibition of Viral Transcription von Ilinykh, Philipp A., Tigabu, Bersabeh, Ivanov, Andrey, Ammosova, Tatiana, Obukhov, Yuri, Garron, Tania, Kumari, Namita, Kovalskyy, Dmytro, Platonov, Maxim O., Naumchik, Vasiliy S., Freiberg, Alexander N., Nekhai, Sergei, Bukreyev, Alexander

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Rift Valley fever virus 78kDa envelope protein attenuates virus replication in macrophage-derived cell lines and viral virulence in mice von Terasaki, Kaori, Kalveram, Birte, Johnson, Kendra N, Juelich, Terry, Smith, Jennifer K, Zhang, Lihong, Freiberg, Alexander N, Makino, Shinji

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Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever von Gowen, Brian B, Juelich, Terry L, Sefing, Eric J, Brasel, Trevor, Smith, Jennifer K, Zhang, Lihong, Tigabu, Bersabeh, Hill, Terence E, Yun, Tatyana, Pietzsch, Colette, Furuta, Yousuke, Freiberg, Alexander N

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The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity von Hage, Adam, Bharaj, Preeti, van Tol, Sarah, Giraldo, Maria I., Gonzalez-Orozco, Maria, Valerdi, Karl M., Warren, Abbey N., Aguilera-Aguirre, Leopoldo, Xie, Xuping, Widen, Steven G., Moulton, Hong M., Lee, Benhur, Johnson, Jeffrey R., Krogan, Nevan J., García-Sastre, Adolfo, Shi, Pei-Yong, Freiberg, Alexander N., Rajsbaum, Ricardo

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TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication von Gonzalez-Orozco, Maria, Tseng, Hsiang-chi, Hage, Adam, Xia, Hongjie, Behera, Padmanava, Afreen, Kazi, Peñaflor-Tellez, Yoatzin, Giraldo, Maria I., Huante, Matthew, Puebla-Clark, Lucinda, van Tol, Sarah, Odle, Abby, Crown, Matthew, Teruel, Natalia, Shelite, Thomas R., Moreno-Contreras, Joaquin, Terasaki, Kaori, Makino, Shinji, Menachery, Vineet, Endsley, Mark, Endsley, Janice J., Najmanovich, Rafael J., Bashton, Matthew, Stephens, Robin, Shi, Pei-Yong, Xie, Xuping, Freiberg, Alexander N., Rajsbaum, Ricardo

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The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection von Escaffre, Olivier, Juelich, Terry L, Smith, Jennifer K, Zhang, Lihong, Bourne, Nigel, Freiberg, Alexander N

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