Emerging Roles of Ceramides in Breast Cancer Biology and Therapy von Pal, Purab, Atilla-Gokcumen, G. Ekin, Frasor, Jonna

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An integrated bioinformatics approach identifies elevated cyclin E2 expression and E2F activity as distinct features of tamoxifen resistant breast tumors von Huang, Lei, Zhao, Shuangping, Frasor, Jonna M, Dai, Yang

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SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer von He, Chenxia, Danes, Jeanne M., Hart, Peter C., Zhu, Yueming, Huang, Yunping, deAbreu, Andre Luelsdorf, O’Brien, Joseph, Mathison, Angela J., Tang, Binwu, Frasor, Jonna M., Wakefield, Lalage M., Ganini, Douglas, Stauder, Erich, Zielonka, Jacek, Gantner, Benjamin N., Urrutia, Raul A., Gius, David, Bonini, Marcelo G.

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Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer von El-Shennawy, Lamiaa, Dubrovskyi, Oleksii, Kastrati, Irida, Danes, Jeanne M, Zhang, Yiqun, Whiteley, Herbert E, Creighton, Chad J, Frasor, Jonna

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Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells von Stender, Joshua D., Nwachukwu, Jerome C., Kastrati, Irida, Kim, Yohan, Strid, Tobias, Yakir, Maayan, Srinivasan, Sathish, Nowak, Jason, Izard, Tina, Rangarajan, Erumbi S., Carlson, Kathryn E., Katzenellenbogen, John A., Yao, Xin-Qiu, Grant, Barry J., Leong, Hon S., Lin, Chin-Yo, Frasor, Jonna, Nettles, Kendall W., Glass, Christopher K.

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Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells von Semina, Svetlana E, Pal, Purab, Kansara, Nidhi S, Huggins, Rosemary J, Alarid, Elaine T, Greene, Geoffrey L, Frasor, Jonna

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Full antagonism of the estrogen receptor without a prototypical ligand side chain von Srinivasan, Sathish, Nwachukwu, Jerome C, Bruno, Nelson E, Dharmarajan, Venkatasubramanian, Goswami, Devrishi, Kastrati, Irida, Novick, Scott, Nowak, Jason, Cavett, Valerie, Zhou, Hai-Bing, Boonmuen, Nittaya, Zhao, Yuechao, Min, Jian, Frasor, Jonna, Katzenellenbogen, Benita S, Griffin, Patrick R, Katzenellenbogen, John A, Nettles, Kendall W

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ASCT2 is a major contributor to serine uptake in cancer cells von Conger, Kelly O., Chidley, Christopher, Ozgurses, Mete Emir, Zhao, Huiping, Kim, Yumi, Semina, Svetlana E., Burns, Philippa, Rawat, Vipin, Lietuvninkas, Lina, Sheldon, Ryan, Ben-Sahra, Issam, Frasor, Jonna, Sorger, Peter K., DeNicola, Gina M., Coloff, Jonathan L.

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CBP Mediates NF-κB-Dependent Histone Acetylation and Estrogen Receptor Recruitment to an Estrogen Response Element in the BIRC3 Promoter von Pradhan, Madhumita, Baumgarten, Sarah C., Bembinster, Leslie A., Frasor, Jonna

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Correlative Analysis of miRNA Expression and Oncotype Dx Recurrence Score in Estrogen Receptor Positive Breast Carcinomas von Emmadi, Rajyasree, Canestrari, Emanuele, Arbieva, Zarema H, Mu, Wenbo, Dai, Yang, Frasor, Jonna, Wiley, Elizabeth

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The Stimulation of HSD17B7 Expression by Estradiol Provides a Powerful Feed-Forward Mechanism for Estradiol Biosynthesis in Breast Cancer Cells von Shehu, Aurora, Albarracin, Constance, Devi, Y. Sangeeta, Luther, Kristin, Halperin, Julia, Le, Jamie, Mao, Jifang, Duan, Rachel W, Frasor, Jonna, Gibori, Geula

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Therapeutic targeting in the estrogen receptor hormonal pathway von Katzenellenbogen, Benita S, Frasor, Jonna

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Update on the Role of NFKB in Promoting Aggressive Phenotypes of Estrogen Receptor-Positive Breast Cancer von Smart, Emily, Semina, Svetlana E, Frasor, Jonna

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Update on the Role of NFκB in Promoting Aggressive Phenotypes of Estrogen Receptor–Positive Breast Cancer von Smart, Emily, Semina, Svetlana E, Frasor, Jonna

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Abstract P4-02-06: Exploiting ceramide homeostasis to target endocrine therapy-resistant breast cancer von Pal, Purab, Millner, Alec, Atilla-Gokcumen, Ekin, Frasor, Jonna

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Abstract 2158: Inhibition of NFkB restores tamoxifen responsiveness in resistant estrogen receptor positive breast cancer in a syngeneic mouse model von Smart, Emily, Kastrati, Irida, Frasor, Jonna

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PHLDA1 expression is controlled by an estrogen receptor-NFκB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres von Kastrati, I, Canestrari, E, Frasor, J

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Abstract P5-11-01: Identification of novel ER and ER-NFκB driven stem-like cell populations in ER+ breast cancer von Semina, Svetlana E., Maienschein-Cline, Mark, Alarid, Elaine T., Sartorius, Carol A., Frasor, Jonna

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Removal of Serum Lipids and Lipid‐Derived Metabolites to Investigate Breast Cancer Cell Biology von Brovkovych, Viktor, Aldrich, Alyssa, Li, Nasi, Atilla‐Gokcumen, G. Ekin, Frasor, Jonna

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NFκB affects estrogen receptor expression and activity in breast cancer through multiple mechanisms von Frasor, Jonna, El-Shennawy, Lamiaa, Stender, Joshua D., Kastrati, Irida

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