The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation von Schweipert, Markus, Nehls, Thomas, Frühauf, Anton, Debarnot, Cecilé, Kumar, Adarsh, Knapp, Stefan, Lermyte, Frederik, Meyer‐Almes, Franz‐Josef

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Design and synthesis of peptides as stabilizers of histone deacetylase 4 von Lill, Annika, Schweipert, Markus, Nehls, Thomas, Wurster, Eva, Lermyte, Frederik, Meyer‐Almes, Franz‐Josef, Schmitz, Katja

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Non-Hydroxamate Zinc-Binding Groups as Warheads for Histone Deacetylases von Frühauf, Anton, Meyer-Almes, Franz-Josef

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Switching the Switch: Ligand Induced Disulfide Formation in HDAC8 von Jänsch, Niklas, Sugiarto, Wisely Oki, Muth, Marius, Kopranovic, Aleksandra, Desczyk, Charlotte, Ballweg, Matthias, Kirschhöfer, Frank, Brenner‐Weiss, Gerald, Meyer‐Almes, Franz‐Josef

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Synthesis and Biological Evaluation of Pyrazoline and Pyrrolidine‐2,5‐dione Hybrids as Potential Antitumor Agents von Tilekar, Kalpana, Upadhyay, Neha, Meyer‐Almes, Franz‐Josef, Loiodice, Fulvio, Anisimova, Natalia Y., Spirina, Tatiana S., Sokolova, Darina V., Smirnova, Galina B., Choe, Jun‐yong, Pokrovsky, Vadim S., Lavecchia, Antonio, S Ramaa, C

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Significance of Five-Membered Heterocycles in Human Histone Deacetylase Inhibitors von Frühauf, Anton, Behringer, Martin, Meyer-Almes, Franz-Josef

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Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments von Petri, László, Ábrányi‐Balogh, Péter, Tímea, Imre, Pálfy, Gyula, Perczel, András, Knez, Damijan, Hrast, Martina, Gobec, Martina, Sosič, Izidor, Nyíri, Kinga, Vértessy, Beáta G., Jänsch, Niklas, Desczyk, Charlotte, Meyer‐Almes, Franz‐Josef, Ogris, Iza, Golič Grdadolnik, Simona, Iacovino, Luca Giacinto, Binda, Claudia, Gobec, Stanislav, Keserű, György M.

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Potent and Selective Non-hydroxamate Histone Deacetylase 8 Inhibitors von Kleinschek, Alexander, Meyners, Christian, Digiorgio, Eros, Brancolini, Claudio, Meyer-Almes, Franz-Josef

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Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids von Jakubkiene, Virginija, Valiulis, Gabrielius Ernis, Schweipert, Markus, Zubriene, Asta, Matulis, Daumantas, Meyer-Almes, Franz-Josef, Tumkevicius, Sigitas

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A Fluorescence‐Lifetime‐Based Binding Assay for Class IIa Histone Deacetylases von Meyners, Christian, Mertens, Monique, Wessig, Pablo, Meyer‐Almes, Franz‐Josef

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Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity von Khetmalis, Yogesh Mahadu, Fathima, Ashna, Schweipert, Markus, Debarnot, Cécile, Bandaru, Naga Venkata Madhusudhan Rao, Murugesan, Sankaranarayanan, Jamma, Trinath, Meyer-Almes, Franz-Josef, Sekhar, Kondapalli Venkata Gowri Chandra

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3‐Chloro‐5‐Substituted‐1,2,4‐Thiadiazoles (TDZs) as Selective and Efficient Protein Thiol Modifiers von Jänsch, Niklas, Frühauf, Anton, Schweipert, Markus, Debarnot, Cécile, Erhardt, Miriam, Brenner‐Weiss, Gerald, Kirschhöfer, Frank, Jasionis, Tomas, Čapkauskaitė, Edita, Zubrienė, Asta, Matulis, Daumantas, Meyer‐Almes, Franz‐Josef

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The enzyme activity of histone deacetylase 8 is modulated by a redox-switch von Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef

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Discrimination between conformational selection and induced fit protein–ligand binding using Integrated Global Fit analysis von Meyer-Almes, Franz-Josef

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Continuous enzyme activity assay for high-throughput classification of histone deacetylase 8 inhibitors von Schweipert, Markus, Amurthavasan, Anuja, Meyer-Almes, Franz-Josef

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Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design von Meyer-Almes, Franz-Josef

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Determination of the binding mechanism of histone deacetylase inhibitors von Meyer‐Almes, Franz‐Josef

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Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets von Baud, Matthias G. J, Leiser, Thomas, Haus, Patricia, Samlal, Sharon, Wong, Ai Ching, Wood, Robert J, Petrucci, Vanessa, Gunaratnam, Mekala, Hughes, Siobhan M, Buluwela, Lakjaya, Turlais, Fabrice, Neidle, Stephen, Meyer-Almes, Franz-Josef, White, Andrew J. P, Fuchter, Matthew J

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Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors von Weston, Claire E, Krämer, Andreas, Colin, Felix, Yildiz, Özkan, Baud, Matthias G. J, Meyer-Almes, Franz-Josef, Fuchter, Matthew J

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Mechanistic Insights into Binding of Ligands with Thiazolidinedione Warhead to Human Histone Deacetylase 4 von Schweipert, Markus, Jänsch, Niklas, Upadhyay, Neha, Tilekar, Kalpana, Wozny, Ewelina, Basheer, Sidra, Wurster, Eva, Müller, Marlene, C S, Ramaa, Meyer-Almes, Franz-Josef

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