Sensing and reacting to microbes through the inflammasomes von Franchi, Luigi, Muñoz-Planillo, Raul, Núñez, Gabriel

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Role of inflammasomes in intestinal inflammation and Crohn's disease von Opipari, Anthony, Franchi, Luigi

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Function of Nod-like receptors in microbial recognition and host defense von Franchi, Luigi, Warner, Neil, Viani, Kyle, Nuñez, Gabriel

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The protein kinase PKR is critical for LPS‐induced iNOS production but dispensable for inflammasome activation in macrophages von He, Yuan, Franchi, Luigi, Núñez, Gabriel

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A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome von Munoz-Planillo, Raul, Franchi, Luigi, Miller, Lloyd S, Nunez, Gabriel

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Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux von Franchi, Luigi, Eigenbrod, Tatjana, Muñoz-Planillo, Raúl, Ozkurede, Ulas, Kim, Yun-Gi, Arindam, Chakrabarti, Gale, Jr, Michael, Silverman, Robert H, Colonna, Marco, Akira, Shizuo, Núñez, Gabriel

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RNase L Activates the NLRP3 Inflammasome during Viral Infections von Chakrabarti, Arindam, Banerjee, Shuvojit, Franchi, Luigi, Loo, Yueh-Ming, Gale, Michael, Núñez, Gabriel, Silverman, Robert H.

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The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes von Kim, Yun-Gi, Kamada, Nobuhiko, Shaw, Michael H., Warner, Neil, Chen, Grace Y., Franchi, Luigi, Núñez, Gabriel

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STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria von Samavati, Lobelia, Rastogi, Ruchi, Du, Wenjin, Hüttemann, Maik, Fite, Alemu, Franchi, Luigi

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Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ von Suzuki, Shiho, Franchi, Luigi, He, Yuan, Muñoz-Planillo, Raul, Mimuro, Hitomi, Suzuki, Toshihiko, Sasakawa, Chihiro, Núñez, Gabriel

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Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages von Suzuki, Shiho, Mimuro, Hitomi, Kim, Minsoo, Ogawa, Michinaga, Ashida, Hiroshi, Toyotome, Takahito, Franchi, Luigi, Suzuki, Masato, Sanada, Takahito, Suzuki, Toshihiko, Tsutsui, Hiroko, Núñez, Gabriel, Sasakawa, Chihiro

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Differential Requirement of P2X7 Receptor and Intracellular K+ for Caspase-1 Activation Induced by Intracellular and Extracellular Bacteria von Franchi, Luigi, Kanneganti, Thirumala-Devi, Dubyak, George R., Núñez, Gabriel

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Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling von Kanneganti, Thirumala-Devi, Lamkanfi, Mohamed, Kim, Yun-Gi, Chen, Grace, Park, Jong-Hwan, Franchi, Luigi, Vandenabeele, Peter, Núñez, Gabriel

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The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands von Kim, Yun-Gi, Park, Jong-Hwan, Shaw, Michael H., Franchi, Luigi, Inohara, Naohiro, Núñez, Gabriel

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Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages von Suzuki, Toshihiko, Franchi, Luigi, Toma, Claudia, Ashida, Hiroshi, Ogawa, Michinaga, Yoshikawa, Yuko, Mimuro, Hitomi, Inohara, Naohiro, Sasakawa, Chihiro, Nuñez, Gabriel

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Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA von Kanneganti, Thirumala-Devi, Body-Malapel, Mathilde, Amer, Amal, Park, Jong-Hwan, Whitfield, Joel, Franchi, Luigi, Taraporewala, Zenobia F., Miller, David, Patton, John T., Inohara, Naohiro, Núñez, Gabriel

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Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf von Amer, Amal, Franchi, Luigi, Kanneganti, Thirumala-Devi, Body-Malapel, Mathilde, Özören, Nesrin, Brady, Graham, Meshinchi, Sasha, Jagirdar, Rajesh, Gewirtz, Andrew, Akira, Shizuo, Núñez, Gabriel

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Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation von Franchi, Luigi, Stoolman, Joshua, Kanneganti, Thirumala-Devi, Verma, Amrisha, Ramphal, Reuben, Núñez, Gabriel

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 von Núñez, Gabriel, Kanneganti, Thirumala-Devi, Özören, Nesrin, Body-Malapel, Mathilde, Amer, Amal, Park, Jong-Hwan, Franchi, Luigi, Whitfield, Joel, Barchet, Winfried, Colonna, Marco, Vandenabeele, Peter, Bertin, John, Coyle, Anthony, Grant, Ethan P, Akira, Shizuo

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Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis von Franchi, Luigi, Monteleone, Ivan, Hao, Ling-Yang, Spahr, Mark A, Zhao, Wenpu, Liu, Xikui, Demock, Kellie, Kulkarni, Aditi, Lesch, Chuck A, Sanchez, Brian, Carter, Laura, Marafini, Irene, Hu, Xiao, Mashadova, Oksana, Yuan, Min, Asara, John M, Singh, Harinder, Lyssiotis, Costas A, Monteleone, Giovanni, Opipari, Anthony W, Glick, Gary D

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