How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project) von Brito-Zerón, Pilar, Acar-Denizli, Nihan, Ng, Wan-Fai, Zeher, Margit, Rasmussen, Astrid, Mandl, Thomas, Seror, Raphaele, Li, Xiaomei, Baldini, Chiara, Gottenberg, Jacques-Eric, Danda, Debashish, Quartuccio, Luca, Priori, Roberta, Hernandez-Molina, Gabriela, Armagan, Berkan, Kruize, Aike A, Kwok, Seung-Ki, Kvarnström, Marika, Praprotnik, Sonja, Sène, Damien, Bartoloni, Elena, Solans, Roser, Rischmueller, Maureen, Suzuki, Yasunori, Isenberg, David A, Valim, Valeria, Wiland, Piotr, Nordmark, Gunnel, Fraile, Guadalupe, Bootsma, Hendrika, Nakamura, Takashi, Giacomelli, Roberto, Devauchelle-Pensec, Valerie, Knopf, Andreas, Bombardieri, Michele, Trevisani, Virginia-Fernandes, Hammenfors, Daniel, Pasoto, Sandra G, Retamozo, Soledad, Gheita, Tamer A, Atzeni, Fabiola, Morel, Jacques, Vollenveider, Cristina, Horvath, Ildiko-Fanny, Sivils, Kathy L, Olsson, Peter, De Vita, Salvatore, Sánchez-Guerrero, Jorge, Kilic, Levent, Wahren-Herlenius, Marie, Mariette, Xavier, Ramos-Casals, Manuel

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Systemic activity and mortality in primary Sjögren syndrome: predicting survival using the EULAR-SS Disease Activity Index (ESSDAI) in 1045 patients von Brito-Zerón, P, Kostov, B, Solans, R, Fraile, G, Suárez-Cuervo, C, Casanovas, A, Rascón, F J, Qanneta, R, Pérez-Alvarez, R, Ripoll, M, Akasbi, M, Pinilla, B, Bosch, J A, Nava-Mateos, J, Díaz-López, B, Morera-Morales, M L, Gheitasi, H, Retamozo, S, Ramos-Casals, M

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Recurrent Idiopathic Membranous Nephropathy: Early Diagnosis by Protocol Biopsies and Treatment with Anti‐CD20 Monoclonal Antibodies von El‐Zoghby, Ziad M., Grande, Joseph P., Fraile, M. G, Norby, S. M., Fervenza, F. C., Cosio, F. G.

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Evaluation of two, commercial, multi-dye, nucleic acid amplification technology tests, for HBV/HCV/HIV-1/HIV-2 and B19V/HAV, for screening blood and plasma for further manufacture von Müller, M. M., Fraile, M. I. G., Hourfar, M. K., Peris, L. B., Sireis, W., Rubin, M. G., López, E. M., Rodriguez, G. T., Seifried, E., Saldanha, J., Schmidt, M.

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How are we treating our systemic patients with primary Sjögren syndrome? Analysis of 1120 patients von Gheitasi, H., Kostov, B., Solans, R., Fraile, G., Suárez-Cuervo, C., Casanovas, A., Rascón, F.J., Qanneta, R., Pérez-Alvarez, R., Ripoll, M., Akasbi, M., Pinilla, B., Bosch, J.A., Nava-Mateos, J., Díaz-López, B., Morera-Morales, M.L., Retamozo, S., Ramos-Casals, M., Brito-Zerón, P.

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SAT0365 Risk Factors for Visual Loss in Giant Cell Arteritis (GCA) von Solans-Laqué, R., Fraile, G., Escalante, B., Fonseca, E., Martinez-Zapico, A., Perez-Conesa, M., Abdilla, M., Montegaudo, M., Caminal, L., Gracia, B., Del Castillo, M.J., Fanlo, P., Ramentol, M.

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Influence of epidemiology and ethnicity on systemic expression of primary Sjögren syndrome in 9974 patients von Retamozo, S., Acar-Denizli, N., Ng, W. Fai, Zeher, M., Rasmussen, A., Seror, R., Li, X., Baldini, C., Gottenberg, J. -E, Danda, D., Quartuccio, L., Priori, R., Hernandez-Molina, G., Armagan, B., Kruize, A. A., Kwok, S. -K, Wahren-Herlenius, M., Praprotnik, S., Sene, D., Bartoloni, E., Solans, R., Rischmueller, M., Mandl, T., Suzuki, Y., Isenberg, D., Valim, V., Wiland, P., Nordmark, Gunnel, Fraile, G., Bootsma, H., Nakamura, T., Giacomelli, R., Devauchelle-Pensee, V., Hofauer, B., Bombardieri, M., Fernandes Moca Trevisani, V., Hammenfors, D., Pasoto, S. G., Gheita, T. A., Atzeni, F., Morel, J., Vollenveider, C., Brito-Zeron, P., Ramos-Casals, M.

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A North-South Worldwide Gradient in Systemic Activity of Primary Sjögren Syndrome: Increased Severe Disease in Patients from Southern Countries von Retamozo, S., Acar-Denizli, N., Ng, W. Fai, Zeher, M., Rasmussen, A., Seror, R., Li, X., Baldini, C., Gottenberg, J. -E, Danda, D., Quartuccio, L., Priori, R., Hernandez-Molina, G., Armagan, B., Kruize, A. A., Kwok, S. -K, Wahren-Herlenius, M., Praprotnik, S., Sene, D., Bartoloni, E., Solans, R., Rischmueller, M., Mandi, T., Suzuki, Y., Isenberg, D., Valim, V., Wiland, P., Nordmark, Gunnel, Fraile, G., Bootsma, H., Nakamura, T., Giacomelli, R., Devauchelle-Pensec, V., Hofauer, B., Bombardieri, M., Fernandes Moca Trevisani, V., Hammenfors, D., Pasoto, S. G., Gheita, T. A., Atzeni, F., Morel, J., Vollenveider, C., Brito-Zeron, P., Ramos-Casals, M.

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SAT0534 Thrombosis and Re-Thrombosis Manifestations in Patients with Behçet Disease. Descriptive Analysis from Regeb Cohort von Rodríguez Carballeira, M., Espinosa, G., Mejía, J., Solans, R., Larrañaga, J., Castillo, M., Rios, R., Nieto, J., Solanich, X., Fonseca, E., Muñoz, F., Fraile, G., Boldava, R., Hurtado, R.

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SAT0174 Clinical and Histological Features in Patients with Permanent Visual Los Due to Biopsy-Proven Giant Cell Arteritis von Solans-Laqué, R., Fraile, G., Monteagudo, M., Caminal, L., Abdilla, M., Fanlo, P.

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FRI0362 Pronostic Factors of Survival in ANCA-Associated Vasculitis (AAV). Changes in The New Century von Rodriguez-Carballeira, M., Fraile, G., Martinez-valle, F., Saez, L., Rios, J.J., Solanich, X., Pasquau, F., Fonseca, E., Zamora, M., Calleja, J.L., Oristrell, J., Frutos, B., Abdilla, M., Castillo, M.J., Caminal, L., Fanlo, P., Garcia-Sanchez, I., Sopeña, B., Lopez-Dupla, M., Perez, A., Solans-Laqué, R.

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FRI0388 Ussefulnes of Bvas and Ffs at Diagnosis To Predict Survival in Anca Associated Vasculitis (AAV) von Solans-Laqué, R., Rodriguez-Carballeira, M., Rios, J., Saez, L., Fraile, G., Solanich, X., Pasquau, F., Oristrell, J., Fonseca, E., Callejas, J.L., Zamora, M., del Castillo, M.J., Frutos, B., Caminal, L., Abdilla, M., Fanlo, P., Garcia-Sanchez, I., Sopeña, B., Lopez-Dupla, M., Perez-Iglesias, A.

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THU0352 Worldwide Heterogeneous Diagnostic Approach To Primary Sjögren Syndrome in 8315 Patients (EULAR-SS Task Force Big Data Sjögren Project) von Brito-Zeron, P., Acar-Denizli, N., Zeher, M., Rasmussen, A., Seror, R., Mandl, T., Li, X., Baldini, C., Gottenberg, J.-E., Danda, D., Quartuccio, L., Priori, R., Hernández-Molina, G., Kruize, A., Valim, V., Kvarnstrom, M., Sene, D., Bartoloni, E., Praprotnik, S., Isenberg, D., Solans, R., Rischmueller, M., Kwok, S.-K., Nordmark, G., Suzuki, Y., Giacomelli, R., Devauchelle-Pensec, V., Bombardieri, M., Hofauer, B., Bootsma, H., Hammenfors, D., Fraile, G., Carsons, S., Gheita, T., Morel, J., Vollenveider, C., Atzeni, F., Retamozo, S., Horvath, I.-F., Sivils, K., Theander, E., Sandhya, P., De Vita, S., Sanchez-Guerrero, J., van der Heijden, E., Moça-Trevisano, V., Wahren-Herlenius, M., Mariette, X., Ramos-Casals, M.

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SAT0287 Ethnic Differences Strongly Influence The Phenotypic Expression of Primary Sjögren: Study of 7887 Patients from 20 Countries on 5 Continents (EULAR-SS Task Force Big Data S... von Brito-Zerόn, P., Acar-Denizli, N., Zeher, M., Rasmussen, A., Seror, R., Mandl, T., Li, X., Baldini, C., Gottenberg, J.-E., Danda, D., Quartuccio, L., Priori, R., Hernández-Molina, G., Kruize, A., Valim, V., Kvarnstrom, M., Sene, D., Gerli, R., Praprotnik, S., Isenberg, D., Solans, R., Rischmueller, M., Park, S.-H., Nordmark, G., Suzuki, Y., Giacomelli, R., Saraux, A., Bombardieri, M., Hofauer, B., Bootsma, H., Hammenfors, D., Fraile, G., Carsons, S., Gheita, T., Morel, J., Vollenveider, C., Atzeni, F., Retamozo, S., Horvath, I.-F., Sivils, K., Theander, E., Sandhya, P., De Vita, S., Sanchez-Guerrero, J., van der Heijden, E., Moça-Trevisano, V., Wahren-Herlenius, M., Mariette, X., Ramos-Casals, M.

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OP0088 Categorization of Baseline Systemic Activity at Diagnosis Using the Essdai Disease Activity States (DAS) in Primary Sjögren Syndrome: Association with Poor Outcomes von Brito Zeron, P., Kostov, B., Solans, R., Fraile, G., Caravia-Durán, D., Maure, B., Rascόn, F.-J., Villar-Navas, B., Ripoll, M., Pinilla, B., Fonseca, E., Akasbi, M., Pérez-de-Lis, M., Jiménez-Heredia, I., de la Red, G., Gato, A., Ramentol, M., Ruedas, A., Díaz-Lόpez, B., Pallarés, L., Gheitasi, H., Ramos-Casals, M.

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FRI0604 Antimitochondrial Antibodies and Antibodies Against Subunits of Pyruvate Dehydrogenase as Serological Markers of Primary Biliary Cirrhosis in Patients with Primary SjöGren... von Fraile, G., Brito Zeron, P., Solans, R., Caravia-Durán, D., Maure, B., Rascόn, F.-J., Lopez-Dupla, M., Ripoll, M., Lόpez-Berastegui, O., Trapiella, L., García-Sánchez, I., Pérez-de-Lis, M., Jiménez-Heredia, I., de la Red, G., Gato, A., Martínez-Valle, F., Nava, J., Díaz-Lόpez, B., Pallarés, L., Gheitasi, H., Ramos-Casals, M.

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FRI0275 Long-Term Survival and Baseline Prognostic Factors in a Wide Series of Patients with AAV from Spain. Usefulness of Prognostic Scores (Revas Study) von Solans-Laqué, R., Rodriguez-Carballeira, M., Fraile, G., Castillo, M.J., Rios, J., Saez, L., Solanich, X., Caminal, L., Oristrell, J., Pasquau, F., Fonseca, E., Calleja, J., Zamora, M., Fanlo, P., Abdilla, M., Garcia, I., Sopeña, B., Lopez-Dupla, M., Pérez, A., Frutos, B.

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THU0408 How we are Treating Our Systemic Patients with Primary Sjögren Syndrome? Analysis of 1120 Patients (GEAS-SS Spanish Registry) von Gheitasi, H., Kostov, B., Solans, R., Fraile, G., Suárez-Cuervo, C., Casanovas, A., Rascόn, F.-J., Qanneta, R., Pérez-Alvarez, R., Ripoll, M., Akasbi, M., Pinilla, B., Bosch, X., Nava-Mateos, J., Díaz-Lόpez, B., Morera-Morales, L., Retamozo, S., Ramos-Casals, M., Brito Zeron, P.

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THU0563 Prognostic Value of the 2014 Hscore in Adult Hemophagocytic Syndrome: Analysis in 111 Consecutive Patients (Reghem-Geas-Semi Spanish Cohort) von Brito Zeron, P., Moral Moral, P., Martínez Zapico, A., Fraile, G., Fonseca, E., Pérez Guerrero, P., Robles, A., Vaquero Herrero, M., Ruiz De Temiño, A., Forner, M.J., Larrañaga, J.R., Prieto, S., Hurtado, R., Ruiz Muñoz, M., Rodriguez, M., Caminal, L., Chamorro, A., Calvo, M.A., Bosch, X., Castro, P., Ramos-Casals, M.

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Henoch Schönlein purpura at diagnosis in 3 adult patients: Acute onset with peripheral nervous system dysfunction von Vasco, P.G, Terrier, B, Calleja, J.L, Fraile, G

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