Interface-guided phenotyping of coding variants in the transcription factor RUNX1 von Ozturk, Kivilcim, Panwala, Rebecca, Sheen, Jeanna, Ford, Kyle, Jayne, Nathan, Portell, Andrew, Zhang, Dong-Er, Hutter, Stephan, Haferlach, Torsten, Ideker, Trey, Mali, Prashant, Carter, Hannah

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Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation von Ford, Kyle, Munson, Brenton P., Fong, Samson H., Panwala, Rebecca, Chu, Wai Keung, Rainaldi, Joseph, Plongthongkum, Nongluk, Arunachalam, Vinayagam, Kostrowicki, Jarek, Meluzzi, Dario, Kreisberg, Jason F., Jensen-Pergakes, Kristen, VanArsdale, Todd, Paul, Thomas, Tamayo, Pablo, Zhang, Kun, Bienkowska, Jadwiga, Mali, Prashant, Ideker, Trey

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Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors von Ford, Kyle M., Panwala, Rebecca, Chen, Dai-Hua, Portell, Andrew, Palmer, Nathan, Mali, Prashant

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Reprogramming MHC specificity by CRISPR-Cas9-assisted cassette exchange von Kelton, William, Waindok, Ann Cathrin, Pesch, Theresa, Pogson, Mark, Ford, Kyle, Parola, Cristina, Reddy, Sai T.

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Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme von Blazeck, John, Karamitros, Christos S., Ford, Kyle, Somody, Catrina, Qerqez, Ahlam, Murray, Kyle, Burkholder, Nathaniel T., Marshall, Nicholas, Sivakumar, Anirudh, Lu, Wei-Cheng, Tan, Bing, Lamb, Candice, Tanno, Yuri, Siddiqui, Menna Y., Ashoura, Norah, Coma, Silvia, Zhang, Xiaoyan M., McGovern, Karen, Kumada, Yoichi, Zhang, Yan Jessie, Manfredi, Mark, Johnson, Kenneth A., D’Arcy, Sheena, Stone, Everett, Georgiou, George

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Functional Genomics via CRISPR–Cas von Ford, Kyle, McDonald, Daniella, Mali, Prashant

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Optical response to low applied pressure in a quantum dot nanocomposite von Ford, Kyle B., Collins, Michael K., Ajami, Nassim E., Dowds, Dominick, Mesyef, Kevin, Trovillion, Jonathan, Al-Chaar, Ghassan, Marsh, Charles P.

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Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme von Triplett, Todd A, Garrison, Kendra C, Marshall, Nicholas, Donkor, Moses, Blazeck, John, Lamb, Candice, Qerqez, Ahlam, Dekker, Joseph D, Tanno, Yuri, Lu, Wei-Cheng, Karamitros, Christos S, Ford, Kyle, Tan, Bing, Zhang, Xiaoyan M, McGovern, Karen, Coma, Silvia, Kumada, Yoichi, Yamany, Mena S, Sentandreu, Enrique, Fromm, George, Tiziani, Stefano, Schreiber, Taylor H, Manfredi, Mark, Ehrlich, Lauren I R, Stone, Everett, Georgiou, George

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Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ -Driven Uveal Melanoma von Paradis, Justine S, Acosta, Monica, Saddawi-Konefka, Robert, Kishore, Ayush, Gomes, Frederico, Arang, Nadia, Tiago, Manoela, Coma, Silvia, Lubrano, Simone, Wu, Xingyu, Ford, Kyle, Day, Chi-Ping, Merlino, Glenn, Mali, Prashant, Pachter, Jonathan A, Sato, Takami, Aplin, Andrew E, Gutkind, J Silvio

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Peroxide-initiated chemical modification of polyolefins: In search of a latent antioxidant von Twigg, Christopher, Ford, Kyle, Parent, J. Scott

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A multilineage screen identifies actionable synthetic lethal interactions in human cancers von Fong, Samson H, Kuenzi, Brent M, Mattson, Nicole M, Lee, John, Sanchez, Kyle, Bojorquez-Gomez, Ana, Ford, Kyle, Munson, Brenton P, Licon, Katherine, Bergendahl, Sarah, Shen, John Paul, Kreisberg, Jason F, Mali, Prashant, Hager, Jeffrey H, White, Michael A, Ideker, Trey

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Integrated genome and tissue engineering enables screening of cancer vulnerabilities in physiologically relevant perfusable ex vivo cultures von Hu, Michael, Lei, Xin Yi, Larson, Jon D., McAlonis, Melissa, Ford, Kyle, McDonald, Daniella, Mach, Krystal, Rusert, Jessica M., Wechsler-Reya, Robert J., Mali, Prashant

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Abstract 2133: Systematic mapping of genetic interactions in human cancer cells reveals context dependent cancer signaling pathways von Fong, Samson H., Kuenzi, Brent M., Lee, John, Sanchez, Kyle, Bojorquez-Gomez, Ana, Ford, Kyle, Munson, Brenton P., Licon, Katherine, Hager, Jeff, Shen, John Paul, Kreisberg, Jason F., Mali, Prashant, Ideker, Trey

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Correction: Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ -Driven Uveal Melanoma von Paradis, Justine S, Acosta, Monica, Saddawi-Konefka, Robert, Kishore, Ayush, Lubrano, Simone, Gomes, Frederico, Arang, Nadia, Tiago, Manoela, Coma, Silvia, Wu, Xingyu, Ford, Kyle, Day, Chi-Ping, Merlino, Glenn, Mali, Prashant, Pachter, Jonathan A, Sato, Takami, Aplin, Andrew E, Gutkind, J Silvio

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Abstract 223: Using physical, genetic and integrated cancer cell maps to investigate head and neck cancer and breast cancer von Kreisberg, Jason F., Zheng, Fan, Fong, Samson, Kuenzi, Brent M., Ford, Kyle, Swaney, Danielle, Kim, Minkyu, Park, Jisoo, Wang, Zhiyong, Pratt, Dexter, Jura, Natalia, Gutkind, Silvio, Mali, Prashant, Krogan, Nevan, Ideker, Trey

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A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC von Goto, Yusuke, Koshizuka, Keiichi, Ando, Toshinori, Izumi, Hiroki, Wu, Xingyu, Sato, Kuniaki, Ishikawa, Tomohiko, Ford, Kyle, Feng, Xiaodong, Wang, Zhiyong, Arang, Nadia, Allevato, Michael M, Kishore, Ayush, Mali, Prashant, Gutkind, J Silvio

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Synthetic Lethal Screens Reveal Co-Targeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma von Paradis, Justine S., Acosta, Monica, Saddawi-Konefka, Robert, Kishore, Ayush, Gomes, Frederico, Arang, Nadia, Tiago, Manoela, Coma, Silvia, Lubrano, Simone, Wu, Xingyu, Ford, Kyle, Day, Chi-Ping, Merlino, Glenn, Mali, Prashant, Pachter, Jonathan A., Sato, Takami, Aplin, Andrew E., Gutkind, J. Silvio

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Reversal of IDO-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme von Triplett, Todd A., Garrison, Kendra C., Marshall, Nicholas, Donkor, Moses, Blazeck, John, Lamb, Candice, Qerqez, Ahlam, Dekker, Joseph D., Tano, Yuri, Wei-Cheng-Lu, Karamitros, Christos S., Ford, Kyle, Tan, Bing, Zhang, Michelle, McGovern, Karen, Coma, Silvia, Kumada, Yoichi, Yamany, Mena Sameh, Sentandreu, Enrique, Fromm, George, Tiziani, Stefano, Schreiber, Taylor H., Manfredi, Mark, Ehrlich, Lauren I. R., Stone, Everett, Georgiou, George

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An analysis of firefighter personal safety alarm effectiveness on the fire ground von Ford, Kyle, Habeeb, Mudeer, Suits, Joelle, Abbasi, Mustafa, Wilson, Preston S., Ezekoye, Ofodike

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Temperature Dependence of the Emission Spectrum of Silicon Nanoparticles in Acetone and Isopropanol Solvents von Al-Chaar, Ghassan, Hoang, Tuan, Dowds, Dominick, Ford, Kyle, Carlson, Thomas, Marsh, Charles

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