Interim analysis of a prospective, randomized trial of Vacuum-Assisted Closure versus the Healthpoint System in the management of pressure ulcers von FORD, Christian N, REINHARD, Elaine R, YEH, Daniel, SYREK, David, DE LAS MORENAS, Antonio, BERGMAN, Susan B, WILLIAMS, Steve, HAMORI, Christine A

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Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis von Burke, Carol A, Dekker, Evelien, Lynch, Patrick, Samadder, N. Jewel, Balaguer, Francesc, Hüneburg, Robert, Burn, John, Castells, Antoni, Gallinger, Steven, Lim, Ramona, Stoffel, Elena M, Gupta, Samir, Henderson, Alex, Kallenberg, Frank G, Kanth, Priyanka, Roos, Victorine H, Ginsberg, Gregory G, Sinicrope, Frank A, Strassburg, Christian P, Van Cutsem, Eric, Church, James, Lalloo, Fiona, Willingham, Field F, Wise, Paul E, Grady, William M, Ford, Molly, Weiss, Jennifer M, Gryfe, Robert, Rustgi, Anil K, Syngal, Sapna, Cohen, Alfred

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MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset von Thomalla, Götz, Simonsen, Claus Z, Boutitie, Florent, Andersen, Grethe, Berthezene, Yves, Cheng, Bastian, Cheripelli, Bharath, Cho, Tae-Hee, Fazekas, Franz, Fiehler, Jens, Ford, Ian, Galinovic, Ivana, Gellissen, Susanne, Golsari, Amir, Gregori, Johannes, Günther, Matthias, Guibernau, Jorge, Häusler, Karl Georg, Hennerici, Michael, Kemmling, André, Marstrand, Jacob, Modrau, Boris, Neeb, Lars, Perez de la Ossa, Natalia, Puig, Josep, Ringleb, Peter, Roy, Pascal, Scheel, Enno, Schonewille, Wouter, Serena, Joaquin, Sunaert, Stefan, Villringer, Kersten, Wouters, Anke, Thijs, Vincent, Ebinger, Martin, Endres, Matthias, Fiebach, Jochen B, Lemmens, Robin, Muir, Keith W, Nighoghossian, Norbert, Pedraza, Salvador, Gerloff, Christian

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Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction von Stähli, Barbara E., Varbella, Ferdinando, Linke, Axel, Schwarz, Bettina, Felix, Stephan B., Seiffert, Moritz, Kesterke, Rahel, Nordbeck, Peter, Witzenbichler, Bernhard, Lang, Irene M., Kessler, Mirjam, Valina, Christian, Dibra, Alban, Rohla, Miklos, Moccetti, Marco, Vercellino, Matteo, Gaede, Luise, Bott-Flügel, Lorenz, Jakob, Philipp, Stehli, Julia, Candreva, Alessandro, Templin, Christian, Schindler, Matthias, Wischnewsky, Manfred, Zanda, Greca, Quadri, Giorgio, Mangner, Norman, Toma, Aurel, Magnani, Giulia, Clemmensen, Peter, Lüscher, Thomas F., Münzel, Thomas, Schulze, P. Christian, Laugwitz, Karl-Ludwig, Rottbauer, Wolfgang, Huber, Kurt, Neumann, Franz-Josef, Schneider, Steffen, Weidinger, Franz, Achenbach, Stephan, Richardt, Gert, Kastrati, Adnan, Ford, Ian, Maier, Willibald, Ruschitzka, Frank

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GLPG1205 for idiopathic pulmonary fibrosis: a phase 2 randomised placebo-controlled trial von Strambu, Irina R, Seemayer, Christian A, Fagard, Liesbeth M-C A, Ford, Paul A, Van der Aa, Tom A K, de Haas-Amatsaleh, Angela A, Modgill, Vikas, Santermans, Eva, Sondag, Eric N, Helmer, Eric G, Maher, Toby M, Costabel, Ulrich, Cottin, Vincent

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Bivalirudin Started during Emergency Transport for Primary PCI von Steg, Philippe Gabriel, van 't Hof, Arnoud, Hamm, Christian W, Clemmensen, Peter, Lapostolle, Frédéric, Coste, Pierre, Ten Berg, Jurrien, Van Grunsven, Pierre, Eggink, Gerrit Jan, Nibbe, Lutz, Zeymer, Uwe, Campo dell' Orto, Marco, Nef, Holger, Steinmetz, Jacob, Soulat, Louis, Huber, Kurt, Deliargyris, Efthymios N, Bernstein, Debra, Schuette, Diana, Prats, Jayne, Clayton, Tim, Pocock, Stuart, Hamon, Martial, Goldstein, Patrick

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Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? von Miller, Ashley M, Purves, David, McConnachie, Alex, Asquith, Darren L, Batty, G David, Burns, Harry, Cavanagh, Jonathan, Ford, Ian, McLean, Jennifer S, Packard, Chris J, Shiels, Paul G, Turner, Helen, Velupillai, Yoga N, Deans, Kevin A, Welsh, Paul, McInnes, Iain B, Sattar, Naveed

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Effect of IV Thrombolysis With Alteplase in Patients With Vessel Occlusion in the WAKE-UP Trial von Galinovic, Ivana, Fiebach, Jochen B, Boutitie, Florent, Cheng, Bastian, Cho, Tae-Hee, Ebinger, Martin, Endres, Matthias, Enzinger, Christian, Fiehler, Jens, Ford, Ian, Gregori, Johannes, Günther, Matthias, Lemmens, Robin, Muir, Keith W, Nighoghossian, N, Roy, Pascal, Simonsen, Claus Z, Thijs, Vincent N, Wouters, Anke, Gerloff, Christian, Thomalla, Götz, Pedraza, Salvador

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Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease von Webb, Thomas R., PhD, Stirrups, Kathleen E., PhD, Stitziel, Nathan O., MD, PhD, Masca, Nicholas G.D., PhD, Kanoni, Stavroula, PhD, Nelson, Christopher P., PhD, Ferrario, Paola G., PhD, Eicher, John D., PhD, Hamby, Stephen E., PhD, Ruusalepp, Arno, MD, PhD, Franzén, Oscar, PhD, Björkegren, Johan L.M., MD, PhD, Schick, Ursula M., PhD, Zhang, He, PhD, Dube, Marie-Pierre, PhD, Goel, Anuj, MSc, Farrall, Martin, MD, Peloso, Gina M., PhD, Do, Ron, PhD, van Iperen, Erik, MSc, Kruppa, Jochen, PhD, Mahajan, Anubha, PhD, Scott, Robert A., PhD, Willenborg, Christina, PhD, Braund, Peter S., PhD, Doney, Alex S.F., MD, PhD, Donnelly, Louise A., PhD, Merlini, Pier A., MD, Duga, Stefano, PhD, Marziliano, Nicola, PhD, Denny, Josh C., MD, MS, El-Mokhtari, Nour Eddine, MD, Franke, Andre, PhD, Heilmann, Stefanie, PhD, Hengstenberg, Christian, MD, Hveem, Kristian, MD, PhD, Jöckel, Karl-Heinz, PhD, Kriebel, Jennifer, PhD, Laugwitz, Karl L., MD, Marouli, Eirini, MSc, Martinelli, Nicola, MD, PhD, McCarthy, Mark I., MD, Van Zuydam, Natalie R., PhD, Meisinger, Christa, MD, MPH, Esko, Tõnu, PhD, Moebus, Susanne, PhD, Morris, Andrew D., MD, Virtamo, Jarma, MD, PhD, Nikpay, Majid, PhD, Provost, Sylvie, MSc, AlQarawi, Alaa, BSc, Robertson, Neil R., MSc, Akinsansya, Karen O., PhD, Reilly, Dermot F., PhD, Vogt, Thomas F., PhD, Kooperberg, Charles, PhD, Jackson, Rebecca D., MD, Stahl, Eli, PhD, Müller-Nurasyid, Martina, PhD, Strauch, Konstantin, PhD, Varga, Tibor V., PhD, Waldenberger, Melanie, PhD, Zeng, Lingyao, MSc, Chowdhury, Rajiv, MD, PhD, Ford, Ian, PhD, Amouyel, Philippe, MD, PhD, Kontto, Jukka, MSSc, Nordestgaard, Børge G., MD, DMSc, Ferrières, Jean, MD, Saleheen, Danish, MBBS, PhD, Surendran, Praveen, PhD, Young, Robin, PhD, Howson, Joanna M.M., PhD, Butterworth, Adam S., PhD, Danesh, John, DPhil, Ardissino, Diego, MD, Bottinger, Erwin P., MD, Erbel, Raimund, MD, Franks, Paul W., PhD, Girelli, Domenico, MD, PhD, Hall, Alistair S., MD, PhD, Hovingh, G. Kees, MD, PhD, Kastrati, Adnan, MD, Lieb, Wolfgang, MD, MSc, Meitinger, Thomas, MD, Melander, Olle, MD, PhD, Metspalu, Andres, MD, PhD, Palmer, Colin N.A., PhD, Peters, Annette, PhD, Rader, Daniel J., MD, Loos, Ruth J.F., PhD, Reiner, Alex P., MD, MSc, Tardif, Jean-Claude, MD, Wareham, Nicholas J., MB, BS, PhD, Watkins, Hugh, MD, PhD, Willer, Cristen J., PhD, Samani, Nilesh J., MD, Schunkert, Heribert, MD, Deloukas, Panos, PhD, Kathiresan, Sekar, MD

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A closely packed system of low-mass, low-density planets transiting Kepler-11 von Lissauer, Jack J., Fabrycky, Daniel C., Ford, Eric B., Borucki, William J., Fressin, Francois, Marcy, Geoffrey W., Orosz, Jerome A., Rowe, Jason F., Torres, Guillermo, Welsh, William F., Batalha, Natalie M., Bryson, Stephen T., Buchhave, Lars A., Caldwell, Douglas A., Carter, Joshua A., Charbonneau, David, Christiansen, Jessie L., Cochran, William D., Desert, Jean-Michel, Dunham, Edward W., Fanelli, Michael N., Fortney, Jonathan J., Gautier III, Thomas N., Geary, John C., Gilliland, Ronald L., Haas, Michael R., Hall, Jennifer R., Holman, Matthew J., Koch, David G., Latham, David W., Lopez, Eric, McCauliff, Sean, Miller, Neil, Morehead, Robert C., Quintana, Elisa V., Ragozzine, Darin, Sasselov, Dimitar, Short, Donald R., Steffen, Jason H.

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A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2 von Albrich, Werner C., Ghosh, Tarini Shankar, Ahearn-Ford, Sinead, Mikaeloff, Flora, Lunjani, Nonhlanhla, Forde, Brian, Suh, Noémie, Kleger, Gian-Reto, Pietsch, Urs, Frischknecht, Manuel, Garzoni, Christian, Forlenza, Rossella, Horgan, Mary, Sadlier, Corinna, Negro, Tommaso Rochat, Pugin, Jérôme, Wozniak, Hannah, Cerny, Andreas, Neogi, Ujjwal, O'Toole, Paul W., O'Mahony, Liam

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Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization–Lancet Neurology Commission von Feigin, Valery L, Abanto, Carlos, Addissie, Adamu, Adilbekov, Yerzhan, Akhmetzhanova, Zauresh, Akpalu, Albert, Ameriso, Sebastian F, Andonova, Silva, Arsovska, Anita, Bakhiet, Moiz, Bath, Philip M, Bereczki, Daniel, Berkowitz, Aaron L, Bernhardt, Julie, Berzina, Guna, Bhavsar, Bhavan, Bohara, Manoj, Čerimagić, Denis, Chen, Christopher, Christensen, Hanne, Correia, Manuel, D'Amelio, Marco, Danielyan, Kristine E, Demarin, Vida, Demchuk, Andrew M, Dichgans, Martin, Donnan, Geoffrey, Ekeng, Gloria, Endres, Matthias, Flomin, Yuriy, Gavidia, Martin, Gaye Saavedra, Andrés, Gebreyohanns, Mehari, Gierlotka, Marek, Giroud, Maurice, Gonçalves, Ivete Pillo, Gongora-Rivera, Fernando, Gunaratne, Padma S, Heldner, Mirjam R, Ibrahim, Etedal, Jee, Sungju, Jiann-Shing, Jeng, Jovanovic, Dejana, Kalani, Rizwan, Kalkonde, Yogeshwar, Kamenova, Saltanat, Karaszewski, Bartosz, Kondybayeva, Aida, Kozera, Grzegorz, Krespi, Yakup, Kruja, Jera, Kutluk, Kursad, Langhorne, Peter, Law, Zhe K, Leung, Thomas W, Liebeskind, David S, Lotufo, Paulo A, Machline-Carrion, M Julia, Marquez-Romero, Juan M, Medina, Marco T, Mihejeva, Illa, Mikulik, Robert, Mirrakhimov, Erkin, Mohl, Stephanie, Munakomi, Sunil, Murphy, Sean, Musa, Kamarul I, Nasreldein, Ahmed, Novarro-Escudero, Nelson, Ogun, Yomi, Oraby, Mohammed I, Ozturk, Serefnur, Pereira, Telmo, Peeters, André, Potpara, Tatjana, Rathore, Farooq A, Sahathevan, Ramesh, Saposnik, Gustavo, Sargento-Freitas, João, Sharma, Mukul, Shaw, Louise, Sheth, Kevin N, Shin, Yong-Il, Shobhana, A, Tedim Cruz, Vitor, Toni, Danilo, Torales, Julio, Towfighi, Amytis, Truelsen, Thomas, Tsiskaridze, Alexander, Useche, Juan N, Vanacker, Peter, Vuletic, Vladimira, Wang, Wenzhi, Wijeratne, Tissa, Wolfe, Charles, Yock-Corrales, Adriana, Yonemoto, Naohiro, Yperzeele, Laetitia, Zagożdżon, Pawel

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Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double‐Blind, Placebo‐Controlled Trials von Neuwelt, C. Michael, Hobbs, Kathryn, Galateanu, Catrinel, Beaudot, Carolyn, Kilgallen, Brian, Batalov, A., Duca, L., Horak, P., Monova, D., Otsa, K., Popova, T., Radulescu, F., Rednic, S., Vezikova, N., Vitek, P., Zainea, C., Huang, C., Kang, S., Lai, N., Shim, S., Zapata, F. Avila, Cavalcanti, F., Agmon‐Levin, N., Kadel, J., Levy, Y., Mevorach, D., Rosner, I., Shobha, V., Zisman, D., Ayesu, K., Chi, J., Clowse, M., Dao, K., Diab, I., Dikranian, A., El‐Shahawy, M., Kao, A., Katz, R., Lawrence‐Ford, T., Merrill, J., Niemer, G., Pickrell, P., Rothfield, N., Snyder, A., Striebich, C., Vo, Q., Littlejohn, G., Perez, L.Carreno, Chakravarty, K., Gonzales, F. Diaz, Davies, K., Doria, A., Fernández‐Nebro, A., Govoni, M., Hachulla, E., Muñoz‐Fernández, S., Pena‐Sagredo, J., Schmidt, R. E., Ucar‐Angulo, E., Westhovens, R., Yee, C. S., Bazela, B., Chudzik, D., Geher, P., Ionescu, R., Kwiatkowska, B., Leszczynski, P., Nalotov, S., Pavel, M., Raskina, T., Rezus, E., Semen, T., Bonfiglioli, R., Baker, M., Chow, A., Clay, C., Conaway, D., Denburg, J., Escalante, A., Fortin, I., Goddard, D., Hemaiden, A., Kalunian, K., Lafyatis, R., Mease, P., Mehta, C., Nascimento, J., Saadeh, C., Valenzuela, G., Alten, R., Braun, J., Dival, L., Espinosa, G., Fernandez, I. Figueroa, Gordon, C., Jacobi, A., Pego‐Reigosa, J. M., Rubbert‐Roth, A., Schroeder, J., Schwarting, A.

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The Warm Neptune GJ 3470b Has a Polar Orbit von Stefànsson, Guđmundur, Mahadevan, Suvrath, Petrovich, Cristobal, Winn, Joshua N., Kanodia, Shubham, Millholland, Sarah C., Maney, Marissa, Cañas, Caleb I., Wisniewski, John, Robertson, Paul, Ninan, Joe P., Ford, Eric B., Bender, Chad F., Blake, Cullen H., Cegla, Heather, Cochran, William D., Diddams, Scott A., Dong, Jiayin, Endl, Michael, Fredrick, Connor, Halverson, Samuel, Hearty, Fred, Hebb, Leslie, Hirano, Teruyuki, Lin, Andrea S. J., Logsdon, Sarah E., Lubar, Emily, McElwain, Michael W., Metcalf, Andrew J., Monson, Andrew, Rajagopal, Jayadev, Ramsey, Lawrence W., Roy, Arpita, Schwab, Christian, Schweiker, Heidi, Terrien, Ryan C., Wright, Jason T.

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Editorial: Sustainable Development Goal 14 - Life Below Water: Towards a Sustainable Ocean von Molony, Brett W., Ford, Alex T., Sequeira, Ana M. M., Borja, Angel, Zivian, Anna Milena, Robinson, Carol, Lønborg, Christian, Escobar-Briones, Elva G., Di Lorenzo, Emanuele, Andersen, Jesper H., Müller, Marius N., Devlin, Michelle J., Failler, Pierre, Villasante, Sebastian, Libralato, Simone, Fortibuoni, Tomaso

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The rapid expansion of Indonesia’s marine protected area requires improvement in management effectiveness von Amkieltiela, Handayani, Christian N., Andradi-Brown, Dominic A., Estradivari, Ford, Amanda K., Beger, Maria, Hakim, Amehr, Muenzel, Dominic K., Carter, Eleanor, Agung, Firdaus, Veverka, Laura, Iqbal, Mohamad, Lazuardi, Muhammad E., Fauzi, Muhammad N., Tranter, Sylvie N., Ahmadia, Gabby N.

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Cryptogenic Stroke and Underlying Atrial Fibrillation von Sanna, Tommaso, Diener, Hans-Christoph, Passman, Rod S, Di Lazzaro, Vincenzo, Bernstein, Richard A, Morillo, Carlos A, Rymer, Marilyn Mollman, Thijs, Vincent, Rogers, Tyson, Beckers, Frank, Lindborg, Kate, Brachmann, Johannes

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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance von Hivert, Marie-France, Scott, Robert A, Grimsby, Jonna L, Chen, Han, Amin, Najaf, Barnes, Daniel, Cadby, Gemma, Hottenga, Jouke-Jan, Ingelsson, Erik, Kanoni, Stavroula, Ladenvall, Claes, Lagou, Vasiliki, Liu, Yongmei, Martinez-Larrad, Maria Teresa, Navarro, Pau, Strawbridge, Rona J, Tanaka, Toshiko, de Andrade, Mariza, Aulchenko, Yurii, Balkau, Beverley, Beilby, John P, Blangero, John, Boban, Mladen, Boomsma, Dorret I, Böttcher, Yvonne, Bouchard, Claude, Budimir, Danijela, Clarke, Robert, Corbatón-Anchuelo, Arturo, Couper, David, Dedoussis, George V, Erdos, Michael R, Eriksson, Johan G, Franzosi, Maria Grazia, Franks, Paul W, Galan, Pilar, de Geus, Eco, Hallmans, Göran, Hansson, Ola, Harris, Tamara B, Hayward, Caroline, Hingorani, Aroon, Johnson, Paul C D, Jukema, J Wouter, Jula, Antti, Kolcic, Ivana, Kumari, Meena, Lakka, Timo, Lannfelt, Lars, Lathrop, G Mark, Lind, Lars, Lobbens, Stéphane, Loos, Ruth J F, Lyssenko, Valeriya, Magnusson, Patrik K E, Marmot, Michael, Meneton, Pierre, Mooser, Vincent, Morken, Mario A, Ong, Ken K, Oostra, Ben A, Palmer, Lyle J, Palotie, Aarno, Peden, John F, Pedersen, Nancy L, Penninx, Brenda, Perola, Markus, Peyser, Patricia A, Räikkönen, Katri, Rehnberg, Emil, Rotter, Jerome I, Rudan, Igor, Ruokonen, Aimo, Saaristo, Timo, Sabater-Lleal, Maria, Salomaa, Veikko, Saxena, Richa, Sennblad, Bengt, Shuldiner, Alan R, Sijbrands, Eric J G, Small, Kerrin S, Smith, Nicholas L, Sun, Yan V, Tuomilehto, Jaakko, Uitterlinden, Andre G, Vikström, Max, Vitart, Veronique, Vohl, Marie-Claude, Voight, Benjamin F, Waeber, Gerard, Wheeler, Eleanor, Widen, Elisabeth, Willemsen, Gonneke, Wilson, James F, Witteman, Jacqueline C M, Yaghootkar, Hanieh, Barroso, Ines, Watanabe, Richard M, Florez, Jose C, Meigs, James B

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The third Sandia fracture challenge: predictions of ductile fracture in additively manufactured metal von Kramer, Sharlotte L. B., Jones, Amanda, Mostafa, Ahmed, Ravaji, Babak, Tancogne-Dejean, Thomas, Roth, Christian C., Bandpay, Maysam Gorji, Pack, Keunhwan, Foster, John T., Behzadinasab, Masoud, Sobotka, James C., McFarland, John M., Stein, Jeremy, Spear, Ashley D., Newell, Pania, Czabaj, Michael W., Williams, Bruce, Simha, Hari, Gesing, Mark, Gilkey, Lindsay N., Jones, Christopher A., Dingreville, Remi, Sanborn, Scott E., Bignell, John L., Cerrone, Albert R., Keim, Vincent, Nonn, Aida, Cooreman, Steven, Thibaux, Philippe, Ames, Nicoli, Connor, Devin O., Parno, Matthew, Davis, Brett, Tucker, Joseph, Coudrillier, Baptiste, Karlson, Kyle N., Ostien, Jakob T., Foulk, James W., Hammetter, Christopher I., Grange, Spencer, Emery, John M., Brown, Judith A., Bishop, Joseph E., Johnson, Kyle L., Ford, Kurtis R., Brinckmann, Steffen, Neilsen, Michael K., Jackiewicz, Jacek, Ravi-Chandar, K., Ivanoff, Thomas, Salzbrenner, Bradley C., Boyce, Brad L.

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The inclusion of fisheries and tourism in marine protected areas to support conservation in Indonesia von Tranter, Sylvie N., Estradivari, Ahmadia, Gabby N., Andradi-Brown, Dominic A., Muenzel, Dominic, Agung, Firdaus, Amkieltiela, Ford, Amanda K., Habibi, Abdullah, Handayani, Christian N., Iqbal, Mohamad, Krueck, Nils C., Lazuardi, Muhammad E., Muawanah, Umi, Papilaya, Renoldy L., Razak, Tries B., Sapari, Agus, Sjahruddin, Fikri F., Veverka, Laura, Yusri, Safran, Beger, Maria

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