Long-Term Stabilization of Maleimide–Thiol Conjugates von Fontaine, Shaun D, Reid, Ralph, Robinson, Louise, Ashley, Gary W, Santi, Daniel V

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A reactivity-based probe of the intracellular labile ferrous iron pool von Spangler, Benjamin, Morgan, Charles W, Fontaine, Shaun D, Vander Wal, Mark N, Chang, Christopher J, Wells, James A, Renslo, Adam R

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A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models von Spangler, Benjamin, Fontaine, Shaun D, Shi, Yihui, Sambucetti, Lidia, Mattis, Aras N, Hann, Byron, Wells, James A, Renslo, Adam R

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High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations von Mott, Bryan T., Eastman, Richard T., Guha, Rajarshi, Sherlach, Katy S., Siriwardana, Amila, Shinn, Paul, McKnight, Crystal, Michael, Sam, Lacerda-Queiroz, Norinne, Patel, Paresma R., Khine, Pwint, Sun, Hongmao, Kasbekar, Monica, Aghdam, Nima, Fontaine, Shaun D., Liu, Dongbo, Mierzwa, Tim, Mathews-Griner, Lesley A., Ferrer, Marc, Renslo, Adam R., Inglese, James, Yuan, Jing, Roepe, Paul D., Su, Xin-zhuan, Thomas, Craig J.

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PEGylated talazoparib enhances therapeutic window of its combination with temozolomide in Ewing sarcoma von Del Pozo, Vanessa, Robles, Andrew J., Fontaine, Shaun D., Liu, Qianqian, Michalek, Joel E., Houghton, Peter J., Kurmasheva, Raushan T.

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In Vitro-In Vivo Correlation for the Degradation of Tetra-PEG Hydrogel Microspheres with Tunable β-Eliminative Crosslink Cleavage Rates von Santi, Daniel V., Ashley, Gary W., Wang, Donghui, Malato, Julia, Schneider, Eric L., Pfaff, Samuel J., Hearn, Brian R., Fontaine, Shaun D., Henise, Jeff, Hann, Byron

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Long-Acting Poly(ADP-ribose) Polymerase Inhibitor Prodrug for Humans von Carreras, Christopher W., Fontaine, Shaun D., Reid, Ralph R., Ashley, Gary W., Santi, Daniel V.

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Prostate-Specific Membrane Antigen Targeted Deep Tumor Penetration of Polymer Nanocarriers von Meher, Niranjan, Ashley, Gary W., Bidkar, Anil P., Dhrona, Suchi, Fong, Cyril, Fontaine, Shaun D., Beckford Vera, Denis R., Wilson, David M., Seo, Youngho, Santi, Daniel V., VanBrocklin, Henry F., Flavell, Robert R.

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PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89 von Beckford Vera, Denis R, Fontaine, Shaun D, VanBrocklin, Henry F, Hearn, Brian R, Reid, Ralph, Ashley, Gary W, Santi, Daniel V

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Attenuation of the Reaction of Michael Acceptors with Biologically Important Nucleophiles von Hearn, Brian R, Fontaine, Shaun D, Schneider, Eric L, Kraemer, Yannick, Ashley, Gary W, Santi, Daniel V

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A Very Long-Acting PARP Inhibitor Suppresses Cancer Cell Growth in DNA Repair-Deficient Tumor Models von Fontaine, Shaun D, Ashley, Gary W, Houghton, Peter J, Kurmasheva, Raushan T, Diolaiti, Morgan, Ashworth, Alan, Peer, Cody J, Nguyen, Ryan, Figg, Sr, William D, Beckford-Vera, Denis R, Santi, Daniel V

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Efficient and Stereocontrolled Synthesis of 1,2,4-Trioxolanes Useful for Ferrous Iron-Dependent Drug Delivery von Fontaine, Shaun D, DiPasquale, Antonio G, Renslo, Adam R

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PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM -Deficient Tumors and Potent Synergy With PARP Inhibitors von Thomas, Anish, Fontaine, Shaun D., Diolaiti, Morgan E., Desai, Parth, Kumar, Rajesh, Takahashi, Nobuyuki, Sciuto, Linda, Nichols, Samantha, Ashworth, Alan, Feng, Felix Y., Ashley, Gary W., Nguyen, Minh, Pommier, Yves, Santi, Daniel V.

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Prospective use of the single-mouse experimental design for the evaluation of PLX038A von Ghilu, Samson, Li, Qilin, Fontaine, Shaun D., Santi, Daniel V., Kurmasheva, Raushan T., Zheng, Siyuan, Houghton, Peter J.

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Primary deuterium kinetic isotope effects prolong drug release and polymer biodegradation in a drug delivery system von Hearn, Brian R., Fontaine, Shaun D., Pfaff, Samuel J., Schneider, Eric L., Henise, Jeff, Ashley, Gary W., Santi, Daniel V.

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Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft von Fontaine, Shaun D., Hann, Byron, Reid, Ralph, Ashley, Gary W., Santi, Daniel. V.

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PLX038: a PEGylated prodrug of SN-38 independent of UGT1A1 activity von Fontaine, Shaun D., Santi, Angelo D., Reid, Ralph, Smith, Philip C., Ashley, Gary W., Santi, Daniel V.

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A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors von Fontaine, Shaun D, Carreras, Christopher W, Reid, Ralph R, Ashley, Gary W, Santi, Daniel V

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Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake von Schneider, Eric L, Hearn, Brian R, Pfaff, Samuel J, Fontaine, Shaun D, Reid, Ralph, Ashley, Gary W, Grabulovski, Stefanie, Strassberger, Verena, Vogt, Lorenz, Jung, Thomas, Santi, Daniel V

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Drug Delivery to the Malaria Parasite Using an Arterolane-Like Scaffold von Fontaine, Shaun D., Spangler, Benjamin, Gut, Jiri, Lauterwasser, Erica M. W., Rosenthal, Philip J., Renslo, Adam R.

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