Roles for novel pharmacological blockers of aquaporins in the treatment of brain oedema and cancer von Yool, Andrea J, Brown, Elizabeth A, Flynn, Gary A

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Synthesis and Pharmacological Evaluation of N-(3-(1H-Indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a Potent Antimitotic Agent von Shetty, Rupa S, Lee, Younghee, Liu, Bin, Husain, Arifa, Joseph, Rhoda W, Lu, Yixin, Nelson, David, Mihelcic, John, Chao, Wenchun, Moffett, Kristofer K, Schumacher, Andreas, Flubacher, Dietmar, Stojanovic, Aleksandar, Bukhtiyarova, Marina, Williams, Ken, Lee, Kyoung-Jin, Ochman, Alexander R, Saporito, Michael S, Moore, William R, Flynn, Gary A, Dorsey, Bruce D, Springman, Eric B, Fujimoto, Ted, Kelly, Martha J

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Application of a novel [3+2] cycloaddition reaction to prepare substituted imidazoles and their use in the design of potent DFG-out allosteric B-Raf inhibitors von Dietrich, Justin, Gokhale, Vijay, Wang, Xiadong, Hurley, Laurence H., Flynn, Gary A.

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Two classes of p38α MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes von Michelotti, Enrique L., Moffett, Kristofer K., Nguyen, Duyan, Kelly, Martha J., Shetty, Rupa, Chai, Xiaomei, Northrop, Katrina, Namboodiri, Variketta, Campbell, Brandon, Flynn, Gary A., Fujimoto, Ted, Hollinger, Frank P., Bukhtiyarova, Marina, Springman, Eric B., Karpusas, Michael

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An acyl-iminium ion cyclization route to a novel conformationally restricted dipeptide mimic: applications to angiotensin-converting enzyme inhibition von Flynn, Gary A, Giroux, Eugene L, Dage, Richard C

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Application of a conformationally restricted Phe-Leu dipeptide mimetic to the design of a combined inhibitor of angiotensin I-converting enzyme and neutral endopeptidase 24.11 von Flynn, Gary A, Beight, Douglas W, Mehdi, Shujaath, Koehl, Jack R, Giroux, Eugene L, French, John F, Hake, Paul W, Dage, Richard C

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PREPARATION AND METHODS OF USE FOR ORTHO-ARYL 5-MEMBERED HETEROARYL-CARBOXAMIDE CONTAINING MULTI-TARGETED KINASE INHIBITORS von Flynn, Gary A

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Small Molecule Inhibitor of ITK Disrupts TCR Signaling and Demonstrates Anti-Tumor Efficacy von Faris, Mary, Malyankar, Uriel M, Zeng, Qingping, Flynn, Gary A, Feuer, Gerold, Kertesz, Nathalie L, Vuga, Danka, Lee, Sandra, Rosario, Darlene, Bot, Adrian

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Stereoselective synthesis of racemic elemanolide dilactones related to vernolepin von Marshall, James A, Flynn, Gary A

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Reductive decyanation of .beta.,.gamma.-epoxy nitriles. New synthesis of .beta.-isopropylidene alcohols von Marshall, James A, Hagan, C. Patrick, Flynn, Gary A

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HIPK INHIBITORS AND METHODS OF USE THEREOF von FLYNN, Gary A, SHEN, Qiang

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HipK4 inhibitors and uses thereof von Bajji, Ashok, Flynn, Gary A, Huynh, Khoi

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HIPK4 INHIBITORS AND USES THEREOF von Bajji, Ashok, Flynn, Gary A, Huynh, Khoi

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PREPARATION AND METHODS OF USE FOR ORTHO-ARYL 5- MEMBERED HETEROARYL-CARBOXAMIDE CONTAINING MULTI-TARGETED KINASE INHIBITORS von FLYNN, Gary A

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PREPARATION AND METHODS OF USE FOR ORTHO-ARYL 5-MEMBERED HETEROARYL-CARBOXAMIDE CONTAINING MULTI-TARGETED KINASE INHIBITORS von Flynn, Gary A

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The synthesis of fluorinated aminophosphonic acid inhibitors of alanine racemase von Flynn, Gary A., Beight, Douglas W., Bohme, Ekkehard H.W., Metcalf, Brian W.

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MODULATORS OF PROTEIN KINASES von Flynn, Gary A, Galatsis, Paul, Werner, Doug, Huntsman, Andrew C, Huynh, Khoi

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Application of conformationally restricted peptidomimetics to modeling the bound conformation of peptide antagonists with the IL-1 receptor von Flynn, Gary A., Akeson, Ann L., Dharanipragada, Ram, Genin, Michael J., Malikayil, J. Antony, Pottorf, Richard, Sabol, Jeffery S., Schreuder, Herman, Tomlinson, Ron, Waid, Phil, Barrett, Ron, Jacobs, Jeff, Yanofsky, Steve

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2 2 JAK2 AND ALK2 INHIBITORS AND METHODS FOR THEIR USE von MOLLARD ALEXIS, FLYNN GARY A, VANKAYALAPATI HARIPRASAD, WARNER STEVEN L, BEARSS DAVID J

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The conversion of a diazolactam to an α-methylenelactam: An entrance to new conformationally restricted inhibitors of angiotensin-converting enzyme von Flynn, Gary A, Beight, Douglas W, Huber, Edward W, Bey, Philippe

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