Target mechanism-based whole-cell screening identifies bortezomib as an inhibitor of caseinolytic protease in mycobacteria von Moreira, Wilfried, Ngan, Grace J Y, Low, Jian Liang, Poulsen, Anders, Chia, Brian C S, Ang, Melgious J Y, Yap, Amelia, Fulwood, Justina, Lakshmanan, Umayal, Lim, Jolander, Khoo, Audrey Y T, Flotow, Horst, Hill, Jeffrey, Raju, Ravikiran M, Rubin, Eric J, Dick, Thomas

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Identification of Chelerythrine as an Inhibitor of BclXL Function von Chan, Shing-Leng, Lee, Mei Chin, Tan, Kuan Onn, Yang, Lay-Kien, Lee, Alex S.Y., Flotow, Horst, Fu, Nai Yang, Butler, Mark S., Soejarto, Doel D., Buss, Antony D., Yu, Victor C.

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Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2 von Somanadhan, Brinda, Kotturi, Santosh R, Yan Leong, Chung, Glover, Robert P, Huang, Yicun, Flotow, Horst, Buss, Antony D, Lear, Martin J, Butler, Mark S

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Establishment of a Novel Whole Animal HTS Technology Platform for Melioidosis Drug Discovery von Lakshmanan, Umayal, Yap, Amelia, Fulwood, Justina, Yichun, Li, Hoon, Sim Siew, Lim, Jolander, Ting, Audrey, Sem, Xiao Hui, Kreisberg, Jason F, Tan, Patrick, Tan, Gladys, Flotow, Horst

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New Antiinfective and Human 5-HT2 Receptor Binding Natural and Semisynthetic Compounds from the Jamaican Sponge Smenospongia aurea von HU, Jin-Feng, SCHETZ, John A., KELLY, Michelle, PENG, Jiang-Nan, ANG, Kenny K. H., FLOTOW, Horst, LEONG, Chung Yan, NG, Siew Bee, BUSS, Antony D., WILKINS, Scott P., HAMANN, Mark T.

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Phosphorylation of SLP-76 by the ZAP-70 Protein-tyrosine Kinase Is Required for T-cell Receptor Function von Wardenburg, Juliane Bubeck, Fu, Chong, Jackman, Janet K., Flotow, Horst, Wilkinson, Sandra E., Williams, David H., Johnson, Robin, Kong, Guanghui, Chan, Andrew C., Findell, Paul R.

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Identification of Molecular Subtypes of Gastric Cancer With Different Responses to PI3-Kinase Inhibitors and 5-Fluorouracil von Lei, Zhengdeng, Tan, Iain Beehuat, Das, Kakoli, Deng, Niantao, Zouridis, Hermioni, Pattison, Sharon, Chua, Clarinda, Feng, Zhu, Guan, Yeoh Khay, Ooi, Chia Huey, Ivanova, Tatiana, Zhang, Shenli, Lee, Minghui, Wu, Jeanie, Ngo, Anna, Manesh, Sravanthy, Tan, Elisabeth, Teh, Bin Tean, So, Jimmy Bok Yan, Goh, Liang Kee, Boussioutas, Alex, Lim, Tony Kiat Hon, Flotow, Horst, Tan, Patrick, Rozen, Steven G

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Overview of High‐Throughput Screening von Entzeroth, Michael, Flotow, Horst, Condron, Peter

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Getting the whole picture: High content screening using three‐dimensional cellular model systems and whole animal assays von Kriston‐Vizi, Janos, Flotow, Horst

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Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques von Koh-Stenta, Xiaoying, Joy, Joma, Poulsen, Anders, Li, Rong, Tan, Yvonne, Shim, Yoonjung, Min, Jung-Hyun, Wu, Liling, Ngo, Anna, Peng, Jianhe, Seetoh, Wei Guang, Cao, Jing, Wee, John Liang Kuan, Kwek, Perlyn Zekui, Hung, Alvin, Lakshmanan, Umayal, Flotow, Horst, Guccione, Ernesto, Hill, Jeffrey

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An integrative approach identified genes associated with drug response in gastric cancer von Zhou, Jin, Yong, Wei-Peng, Yap, Chui Sun, Vijayaraghavan, Aadhitthya, Sinha, Rohit Anthony, Singh, Brijesh Kumar, Xiu, Sam, Manesh, Sravanthy, Ngo, Anna, Lim, Andrea, Ang, Carolyn, Xie, Chen, Wong, Foong Ying, Lin, Suling J, Wan, Wei Keat, Tan, Iain Beehuat, Flotow, Horst, Tan, Patrick, Lim, Kiat-Hon, Yen, Paul Michael, Goh, Liang Kee

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Generation of Active Bovine Terminal Deoxynucleotidyl Transferase (TdT) in E.coli von Kuan, Wee Liang, Joy, Joma, Mee, Ng Fui, Perlyn, Kwek Zekui, Wen, Then Siew, Nguen, Thuy, James, Joanne, Chai, Elaine, Flotow, Horst, Crasta, Sharon, Chua, Kelvin, Peng, Ng Sok, Hill, Jeffrey

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Analysis of p53 binding to DNA by fluorescence imaging microscopy von Ong, Hwee Jing, Siau, Jia Wei, Zhang, Jing Bo, Hong, Minghui, Flotow, Horst, Ghadessy, Farid

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Stat5a Serine Phosphorylation von Beuvink, Iwan, Hess, Daniel, Flotow, Horst, Hofsteenge, Jan, Groner, Bernd, Hynes, Nancy E.

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Abstract 1200: Molecular subtypes of gastric cancer show systematic differences in response to PI3K inhibitors and fluorouracil von Lei, Zengdeng, Deng, Nian Tao, Zouridis, Hermioni, Tan, Iain Beehaut, Ooi, Chia Huey, Ivanova, Tatiana, Zhang, Shenli, Lee, Minghui, Wu, Jeanie, Ngo, Anna, Manesh, Sravanthy, Boussioutas, Alex, Teh, Bin Tean, Goh, Liang Kee, Flotow, Horst, Tan, Patrick, Rozen, Steven G.

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An Automated High-Content Screening Image Analysis Pipeline for the Identification of Selective Autophagic Inducers in Human Cancer Cell Lines von Kriston-Vizi, Janos, Lim, Ching Aeng, Condron, Peter, Chua, Kelvin, Wasser, Martin, Flotow, Horst

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Target Mechanism-Based Whole-Cell Screening Identifies Bortezomib as an Inhibitor of Caseinolytic Protease in Mycobacteria von Moreira, Wilfried, Ngan, Grace J. Y, Low, Jian Liang, Poulsen, Anders, Chia, Brian C. S, Ang, Melgious J. Y, Yap, Amelia, Fulwood, Justina, Lakshmanan, Umayal, Lim, Jolander, Khoo, Audrey Y. T, Flotow, Horst, Hill, Jeffrey, Raju, Ravikiran M, Rubin, Eric J, Dick, Thomas

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Stat5a serine phosphorylation. Serine 779 is constitutively phosphorylated in the mammary gland, and serine 725 phosphorylation influences prolactin-stimulated in vitro DNA binding... von Beuvink, I, Hess, D, Flotow, H, Hofsteenge, J, Groner, B, Hynes, N E

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Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver von FLOTOW, H, THOMAS, G

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Phosphate groups as substrate determinants for casein kinase I action von FLOTOW, H, GRAVES, P. R, WANG, A, FIOL, C. J, ROESKE, R. W, ROACH, P. J

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