RifamycinMode of Action, Resistance, and Biosynthesis von Floss, Heinz G, Yu, Tin-Wein

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The Biosynthetic Gene Cluster of the Maytansinoid Antitumor Agent Ansamitocin from Actinosynnema pretiosum von Yu, Tin-Wein, Bai, Linquan, Clade, Dorothee, Hoffmann, Dietmar, Toelzer, Sabine, Trinh, Khue Q., Xu, Jun, Moss, Steven J., Leistner, Eckhard, Floss, Heinz G.

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Identification of tailoring genes involved in the modification of the polyketide backbone of rifamycin B by Amycolatopsis mediterranei S699 von Xu, Jun, Wan, Eva, Kim, Chang-Joon, Floss, Heinz G, Mahmud, Taifo

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Gene Cluster Responsible for Validamycin Biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008 von Yu, Yi, Bai, Linquan, Minagawa, Kazuyuki, Jian, Xiaohong, Li, Lei, Li, Jialiang, Chen, Shuangya, Cao, Erhu, Mahmud, Taifo, Floss, Heinz G, Zhou, Xiufen, Deng, Zixin

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Phenazine Biosynthesis in Pseudomonas fluorescens:  Branchpoint from the Primary Shikimate Biosynthetic Pathway and Role of Phenazine-1,6-dicarboxylic Acid von MCDONALD, Matthew, MAVRODI, Dmitri V., THOMASHOW, Linda S., FLOSS, Heinz G.

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Functional Expression of Genes Involved in the Biosynthesis of the Novel Polyketide Chain Extension Unit, Methoxymalonyl-Acyl Carrier Protein, and Engineered Biosynthesis of 2-Desm... von Kato, Yasuo, Bai, Linquan, Xue, Qun, Revill, W. Peter, Yu, Tin-Wein, Floss, Heinz G.

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Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in... von Yu, T W, Muller, R, Muller, M, Zhang, X, Draeger, G, Kim, C G, Leistner, E, Floss, H G

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Direct Evidence That the Rifamycin Polyketide Synthase Assembles Polyketide Chains Processively von Yu, Tin-Wein, Shen, Yuemao, Doi-Katayama, Yukiko, Tang, Li, Park, Cheonseok, Moore, Bradley S., Hutchinson, C. Richard, Floss, Heinz G.

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Characterization of the Early Stage Aminoshikimate Pathway in the Formation of 3-Amino-5-hydroxybenzoic Acid:  The RifN Protein Specifically Converts Kanosamine into Kanosamine 6-P... von Arakawa, Kenji, Müller, Rolf, Mahmud, Taifo, Yu, Tin-Wein, Floss, Heinz G

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Isolation and characterization of 27- O-demethylrifamycin SV methyltransferase provides new insights into the post-PKS modification steps during the biosynthesis of the antitubercu... von Xu, Jun, Mahmud, Taifo, Floss, Heinz G

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Antibiotic biosynthesis: from natural to unnatural compounds von FLOSS, H. G

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Ectopic Expression of the Minimal whiE Polyketide Synthase Generates a Library of Aromatic Polyketides of Diverse Sizes and Shapes von Shen, Yuemao, Yoon, Pall, Yu, Tin-Wein, Floss, Heinz G., Hopwood, David, Moore, Bradley S.

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Lessons from the rifamycin biosynthetic gene cluster von Floss, Heinz G, Yu, Tin-Wein

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Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry von Liu, Zhongfa, Floss, Heinz G., Cassady, John M., Chan, Kenneth K.

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Tritiated Chiral Alkanes as Substrates for Soluble Methane Monooxygenase from Methylococcus capsulatus (Bath):  Probes for the Mechanism of Hydroxylation von Valentine, Ann M, Wilkinson, Barrie, Liu, Katherine E, Komar-Panicucci, Sonja, Priestley, Nigel D, Williams, Philip G, Morimoto, Hiromi, Floss, Heinz G, Lippard, Stephen J

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Occurrence and non-detectability of maytansinoids in individual plants of the genera Maytenus and Putterlickia von Pullen, Christian B, Schmitz, Petra, Hoffmann, Dietmar, Meurer, Kristina, Boettcher, Theresa, von Bamberg, Daniel, Pereira, Ana Maria, de Castro França, Suzelei, Hauser, Manfred, Geertsema, Henk, van Wyk, Abraam, Mahmud, Taifo, Floss, Heinz G, Leistner, Eckhard

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Mechanism of Taxadiene Synthase, a Diterpene Cyclase That Catalyzes the First Step of Taxol Biosynthesis in Pacific Yew von Lin, Xiaoyan, Hezari, Mehri, Koepp, Alfred E, Floss, Heinz G, Croteau, Rodney

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Biosynthetic studies on the α-glucosidase inhibitor acarbose: the chemical synthesis of dTDP-4-amino-4,6-dideoxy-α- d-glucose von Bowers, Simeon G., Mahmud, Taifo, Floss, Heinz G.

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Detection of a Phenylalanine Aminomutase in Cell-Free Extracts of Taxus brevifolia and Preliminary Characterization of Its Reaction von Walker, Kevin D, Floss, Heinz G

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A Concerted Mechanism for Ethane Hydroxylation by the Particulate Methane Monooxygenase from Methylococcus capsulatus (Bath) von Wilkinson, Barrie, Zhu, Mei, Priestley, Nigel D, Nguyen, H.-Hoa T, Morimoto, Hiromi, Williams, Philip G, Chan, Sunney I, Floss, Heinz G

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