Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6 von Porter, Nicholas J, Wagner, Florence F, Christianson, David W

Volltext

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias von Hinze, Laura, Pfirrmann, Maren, Karim, Salmaan, Degar, James, McGuckin, Connor, Vinjamur, Divya, Sacher, Joshua, Stevenson, Kristen E., Neuberg, Donna S., Orellana, Esteban, Stanulla, Martin, Gregory, Richard I., Bauer, Daniel E., Wagner, Florence F., Stegmaier, Kimberly, Gutierrez, Alejandro

Volltext

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability von Bhaskara, Srividya, Knutson, Sarah K., Jiang, Guochun, Chandrasekharan, Mahesh B., Wilson, Andrew J., Zheng, Siyuan, Yenamandra, Ashwini, Locke, Kimberly, Yuan, Jia-ling, Bonine-Summers, Alyssa R., Wells, Christina E., Kaiser, Jonathan F., Washington, M. Kay, Zhao, Zhongming, Wagner, Florence F., Sun, Zu-Wen, Xia, Fen, Holson, Edward B., Khabele, Dineo, Hiebert, Scott W.

Volltext

Roles of glycogen synthase kinase 3 alpha and calcineurin in regulating the ability of sperm to fertilize eggs von Dey, Souvik, Eisa, Alaa, Kline, Douglas, Wagner, Florence F., Abeysirigunawardena, Sanjaya, Vijayaraghavan, Srinivasan

Volltext

In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs von Wang, Changning, Schroeder, Frederick A, Wey, Hsiao-Ying, Borra, Ronald, Wagner, Florence F, Reis, Surya, Kim, Sung Won, Holson, Edward B, Haggarty, Stephen J, Hooker, Jacob M

Volltext

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy von Ferguson, Bradley S., Harrison, Brooke C., Jeong, Mark Y., Reid, Brian G., Wempe, Michael F., Wagner, Florence F., Holson, Edward B., McKinsey, Timothy A.

Volltext

Small Molecule Inhibitors of Zinc-dependent Histone Deacetylases von Wagner, Florence F., Weїwer, Michel, Lewis, Michael C., Holson, Edward B.

Volltext

Selective HDAC inhibition for the disruption of latent HIV-1 infection von Barton, Kirston M, Archin, Nancie M, Keedy, Kara S, Espeseth, Amy S, Zhang, Yan-ling, Gale, Jennifer, Wagner, Florence F, Holson, Edward B, Margolis, David M

Volltext

Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways von Stump, Benjamin, Shrestha, Shikshya, Lamattina, Anthony M, Louis, Pierce H, Cho, Woohyun, Perrella, Mark A, Ai, Xingbin, Rosas, Ivan O, Wagner, Florence F, Priolo, Carmen, Astin, Jonathan, El-Chemaly, Souheil

Volltext

MISCAST: MIssense variant to protein StruCture Analysis web SuiTe von Iqbal, Sumaiya, Hoksza, David, Pérez-Palma, Eduardo, May, Patrick, Jespersen, Jakob B, Ahmed, Shehab S, Rifat, Zaara T, Heyne, Henrike O, Rahman, M Sohel, Cottrell, Jeffrey R, Wagner, Florence F, Daly, Mark J, Campbell, Arthur J, Lal, Dennis

Volltext

HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury von Aufhauser, David D., Hernandez, Paul, Concors, Seth J., O’Brien, Ciaran, Wang, Zhonglin, Murken, Douglas R., Samanta, Arabinda, Beier, Ulf H., Krumeich, Lauren, Bhatti, Tricia R., Wang, Yanfeng, Ge, Guanghui, Wang, Liqing, Cheraghlou, Shayan, Wagner, Florence F., Holson, Edward B., Kalin, Jay H., Cole, Philip A., Hancock, Wayne W., Levine, Matthew H.

Volltext

AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice von Pan, Jen Q, Lewis, Michael C, Ketterman, Josh K, Clore, Elizabeth L, Riley, Misha, Richards, Keenan R, Berry-Scott, Erin, Liu, Xiulin, Wagner, Florence F, Holson, Edward B, Neve, Rachael L, Biechele, Travis L, Moon, Randall T, Scolnick, Edward M, Petryshen, Tracey L, Haggarty, Stephen J

Volltext

Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition von Sleiman, Sama F, Olson, David E, Bourassa, Megan W, Karuppagounder, Saravanan S, Zhang, Yan-Ling, Gale, Jennifer, Wagner, Florence F, Basso, Manuela, Coppola, Giovanni, Pinto, John T, Holson, Edward B, Ratan, Rajiv R

Volltext

HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination von Strebl, Martin G, Campbell, Arthur J, Zhao, Wen-Ning, Schroeder, Frederick A, Riley, Misha M, Chindavong, Peter S, Morin, Thomas M, Haggarty, Stephen J, Wagner, Florence F, Ritter, Tobias, Hooker, Jacob M

Volltext

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells von Kubicek, Stefan, Gilbert, Joshua C, Fomina-Yadlin, Dina, Gitlin, Alexander D, Yuan, Yuan, Wagner, Florence F, Holson, Edward B, Luo, Tuoping, Lewis, Timothy A, Taylor, Bradley, Gupta, Supriya, Shamji, Alykhan F, Wagner, Bridget K, Clemons, Paul A, Schreiber, Stuart L

Volltext

A Fast-Binding, Functionally Reversible, COX‑2 Radiotracer for CNS PET Imaging von Placzek, Michael S., Wilton, Daniel K., Weïwer, Michel, Manter, Mariah A., Reid, Sarah E., Meyer, Christopher J., Campbell, Arthur J., Bajrami, Besnik, Bigot, Antoine, Bricault, Sarah, Fayet, Agathe, Frouin, Arnaud, Gergits, Frederick, Gupta, Mehak, Jiang, Wei, Melanson, Michelle, Romano, Chiara D., Riley, Misha M., Wang, Jessica M., Wey, Hsiao-Ying, Wagner, Florence F., Stevens, Beth, Hooker, Jacob M.

Volltext

Discovery of a structural class of antibiotics with explainable deep learning von Wong, Felix, Zheng, Erica J., Valeri, Jacqueline A., Donghia, Nina M., Anahtar, Melis N., Omori, Satotaka, Li, Alicia, Cubillos-Ruiz, Andres, Krishnan, Aarti, Jin, Wengong, Manson, Abigail L., Friedrichs, Jens, Helbig, Ralf, Hajian, Behnoush, Fiejtek, Dawid K., Wagner, Florence F., Soutter, Holly H., Earl, Ashlee M., Stokes, Jonathan M., Renner, Lars D., Collins, James J.

Volltext

Autism-Associated Shank3 Is Essential for Homeostatic Compensation in Rodent V1 von Tatavarty, Vedakumar, Torrado Pacheco, Alejandro, Groves Kuhnle, Chelsea, Lin, Heather, Koundinya, Priya, Miska, Nathaniel J., Hengen, Keith B., Wagner, Florence F., Van Hooser, Stephen D., Turrigiano, Gina G.

Volltext

Progress in Understanding and Treating SCN2A-Mediated Disorders von Sanders, Stephan J., Campbell, Arthur J., Cottrell, Jeffrey R., Moller, Rikke S., Wagner, Florence F., Auldridge, Angie L., Bernier, Raphael A., Catterall, William A., Chung, Wendy K., Empfield, James R., George, Alfred L., Hipp, Joerg F., Khwaja, Omar, Kiskinis, Evangelos, Lal, Dennis, Malhotra, Dheeraj, Millichap, John J., Otis, Thomas S., Petrou, Steven, Pitt, Geoffrey, Schust, Leah F., Taylor, Cora M., Tjernagel, Jennifer, Spiro, John E., Bender, Kevin J.

Volltext

Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants von Iqbal, Sumaiya, Pérez-Palma, Eduardo, Jespersen, Jakob B., May, Patrick, Hoksza, David, Heyne, Henrike O., Ahmed, Shehab S., Rifat, Zaara T., Rahman, M. Sohel, Lage, Kasper, Palotie, Aarno, Cottrell, Jeffrey R., Wagner, Florence F., Daly, Mark J., Campbell, Arthur J., Lal, Dennis

Volltext