The support of human genetic evidence for approved drug indications von Nelson, Matthew R, Tipney, Hannah, Painter, Jeffery L, Shen, Judong, Nicoletti, Paola, Shen, Yufeng, Floratos, Aris, Sham, Pak Chung, Li, Mulin Jun, Wang, Junwen, Cardon, Lon R, Whittaker, John C, Sanseau, Philippe

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geWorkbench: an open source platform for integrative genomics von Floratos, Aris, Smith, Kenneth, Ji, Zhou, Watkinson, John, Califano, Andrea

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Genomewide Pharmacogenetics of Bisphosphonate‐Induced Osteonecrosis of the Jaw: The Role of RBMS3 von Nicoletti, Paola, Cartsos, Vassiliki M., Palaska, Penelope K., Shen, Yufeng, Floratos, Aris, Zavras, Athanasios I.

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Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs von Urban, Thomas J, Shen, Yufeng, Stolz, Andrew, Chalasani, Naga, Fontana, Robert J, Rochon, James, Ge, Dongliang, Shianna, Kevin V, Daly, Ann K, Lucena, M Isabel, Nelson, Matthew R, Molokhia, Mariam, Aithal, Guruprasad P, Floratos, Aris, Pe’er, Itsik, Serrano, Jose, Bonkovsky, Herbert, Davern, Timothy J, Lee, William M, Navarro, Victor J, Talwalkar, Jayant A, Goldstein, David B, Watkins, Paul B

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Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes von Behr, Elijah R, Ritchie, Marylyn D, Tanaka, Toshihiro, Kääb, Stefan, Crawford, Dana C, Nicoletti, Paola, Floratos, Aris, Sinner, Moritz F, Kannankeril, Prince J, Wilde, Arthur A M, Bezzina, Connie R, Schulze-Bahr, Eric, Zumhagen, Sven, Guicheney, Pascale, Bishopric, Nanette H, Marshall, Vanessa, Shakir, Saad, Dalageorgou, Chrysoula, Bevan, Steve, Jamshidi, Yalda, Bastiaenen, Rachel, Myerburg, Robert J, Schott, Jean-Jacques, Camm, A John, Steinbeck, Gerhard, Norris, Kris, Altman, Russ B, Tatonetti, Nicholas P, Jeffery, Steve, Kubo, Michiaki, Nakamura, Yusuke, Shen, Yufeng, George, Jr, Alfred L, Roden, Dan M

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ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs von Nicoletti, Paola, Bansal, Mukesh, Lefebvre, Celine, Guarnieri, Paolo, Shen, Yufeng, Pe'er, Itsik, Califano, Andrea, Floratos, Aris

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A curated collection of human vaccination response signatures von Smith, Kenneth C., Chawla, Daniel G., Dhillon, Bhavjinder K., Ji, Zhou, Vita, Randi, van der Leest, Eva C., Weng, Jing Yi Jessica, Tang, Ernest, Abid, Amani, Peters, Bjoern, Hancock, Robert E. W., Floratos, Aris, Kleinstein, Steven H.

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Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer von Myer, Parvathi A., Kim, Hyunjin, Blümel, Anna M., Finnegan, Ellen, Kel, Alexander, Thompson, Taylor V., Greally, John M., Prehn, Jochen HM, O’Connor, Darran P., Friedman, Richard A., Floratos, Aris, Das, Sudipto

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iTools: a framework for classification, categorization and integration of computational biology resources von Dinov, Ivo D, Rubin, Daniel, Lorensen, William, Dugan, Jonathan, Ma, Jeff, Murphy, Shawn, Kirschner, Beth, Bug, William, Sherman, Michael, Floratos, Aris, Kennedy, David, Jagadish, H V, Schmidt, Jeanette, Athey, Brian, Califano, Andrea, Musen, Mark, Altman, Russ, Kikinis, Ron, Kohane, Isaac, Delp, Scott, Parker, D Stott, Toga, Arthur W

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Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles von Lucena, M. Isabel, Molokhia, Mariam, Shen, Yufeng, Urban, Thomas J, Aithal, Guruprasad P, Andrade, Raúl J, Day, Christopher P, Ruiz–Cabello, Francisco, Donaldson, Peter T, Stephens, Camilla, Pirmohamed, Munir, Romero–Gomez, Manuel, Navarro, Jose Maria, Fontana, Robert J, Miller, Michael, Groome, Max, Bondon–Guitton, Emmanuelle, Conforti, Anita, Stricker, Bruno H.C, Carvajal, Alfonso, Ibanez, Luisa, Yue, Qun–Ying, Eichelbaum, Michel, Floratos, Aris, Pe'er, Itsik, Daly, Mark J, Goldstein, David B, Dillon, John F, Nelson, Matthew R, Watkins, Paul B, Daly, Ann K

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Sa006 MULTI-OMIC ANALYSIS REVEALS DISTINCT MOLECULAR DIFFERENCES BETWEEN AFRICAN AND EUROPEAN ANCESTRY PATIENTS WITH COLORECTAL CANCER von Myer, Parvathi A., Kim, Hyunjin, Finnegan, Ellen, Kel, Alexander, Thompson, Taylor V., Greally, John, Friedman, Richard A., Floratos, Aris, Das, Sudipto

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Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort von Nicoletti, Paola, Carr, Daniel F., Barrett, Sarah, McEvoy, Laurence, Friedmann, Peter S., Shear, Neil H., Nelson, Matthew R., Chiriac, Anca M., Blanca-López, Natalia, Cornejo-García, José A., Gaeta, Francesco, Nakonechna, Alla, Torres, Maria J., Caruso, Cristiano, Valluzzi, Rocco L., Floratos, Aris, Shen, Yufeng, Pavlos, Rebecca K., Phillips, Elizabeth J., Demoly, Pascal, Romano, Antonino, Blanca, Miguel, Pirmohamed, Munir

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Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions von Nicoletti, Paola, Barrett, Sarah, McEvoy, Laurence, Daly, Ann K., Aithal, Guruprasad, Lucena, M. Isabel, Andrade, Raul J., Wadelius, Mia, Hallberg, Pär, Stephens, Camilla, Bjornsson, Einar S., Friedmann, Peter, Kainu, Kati, Laitinen, Tarja, Marson, Anthony, Molokhia, Mariam, Phillips, Elizabeth, Pichler, Werner, Romano, Antonino, Shear, Neil, Sills, Graeme, Tanno, Luciana K., Swale, Ashley, Floratos, Aris, Shen, Yufeng, Nelson, Matthew R., Watkins, Paul B., Daly, Mark J., Morris, Andrew P., Alfirevic, Ana, Pirmohamed, Munir

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Identification of candidate genes for familial early-onset essential tremor von Liu, Xinmin, Hernandez, Nora, Kisselev, Sergey, Floratos, Aris, Sawle, Ashley, Ionita-Laza, Iuliana, Ottman, Ruth, Louis, Elan D, Clark, Lorraine N

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HLA-DRB116: 01-DQB105: 02 is a novel genetic risk factor for flupirtine-induced liver injury von Nicoletti, Paola, Werk, Anneke N, Sawle, Ashley, Shen, Yufeng, Urban, Thomas J, Coulthard, Sally A, Bjornsson, Einar S, Cascorbi, Ingolf, Floratos, Aris, Stammschulte, Thomas, Gundert-Remy, Ursula, Nelson, Matthew R, Aithal, Guruprasad P, Daly, Ann K

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Combinatorial pattern discovery in biological sequences: the TEIRESIAS algorithm. [Erratum: 1998, v. 14 (2), p. 229.] von Rigoutsos, I, Floratos, A

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Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort von Nicoletti, Paola, Carr, Daniel, Barrett, Sarah, Mcevoy, Laurence, Friedmann, Peter, Shear, Neil, Nelson, Matthew, Chiriac, Anca, Blanca-López, Natalia, Cornejo-García, José, Gaeta, Francesco, Nakonechna, Alla, Torres, Maria, Caruso, Cristiano, Valluzzi, Rocco, Floratos, Aris, Shen, Yufeng, Pavlos, Rebecca, Phillips, Elizabeth, Demoly, Pascal, Romano, Antonino, Blanca, Miguel, Pirmohamed, Munir

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HLA-B5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin von Daly, Ann K, Donaldson, Peter T, Bhatnagar, Pallav, Shen, Yufeng, Pe'er, Itsik, Floratos, Aris, Daly, Mark J, Goldstein, David B, John, Sally, Nelson, Matthew R, Graham, Julia, Park, B Kevin, Dillon, John F, Bernal, William, Cordell, Heather J, Pirmohamed, Munir, Aithal, Guruprasad P, Day, Christopher P

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Using systems and structure biology tools to dissect cellular phenotypes von Floratos, Aris, Honig, Barry, Pe'er, Dana, Califano, Andrea

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Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions von Nicoletti, Paola, Barrett, Sarah, McEvoy, Laurence, Daly, Ann K, Aithal, Guruprasad, Lucena, M Isabel, Andrade, Raul J, Wadelius, Mia, Hallberg, Pär, Stephens, Camilla, Bjornsson, Einar S, Friedmann, Peter, Kainu, Kati, Laitinen, Tarja, Marson, Anthony, Molokhia, Mariam, Phillips, Elizabeth, Pichler, Werner, Romano, Antonino, Shear, Neil, Sills, Graeme, Tanno, Luciana K, Swale, Ashley, Floratos, Aris, Shen, Yufeng, Nelson, Matthew R, Watkins, Paul B, Daly, Mark J, Morris, Andrew P, Alfirevic, Ana, Pirmohamed, Munir

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