Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor von HEINRICH, Michael C, MAKI, Robert G, FLETCHER, Christopher D. M, XIN HUANG, COHEN, Darrel P, BAUM, Charles M, DEMETRI, George D, CORLESS, Christopher L, ANTONESCU, Cristina R, HARLOW, Amy, GRIFFITH, Diana, TOWN, Ajia, MCKINLEY, Arin, OU, Wen-Bin, FLETCHER, Jonathan A

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Long-Term Results From a Randomized Phase II Trial of Standard- Versus Higher-Dose Imatinib Mesylate for Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Ex... von BLANKE, Charles D, DEMETRI, George D, WEHRE, Elisabeth, NIKOLOVA, Zariana, JOENSUU, Heikki, VON MEHREN, Margaret, HEINRICH, Michael C, EISENBERG, Burton, FLETCHER, Jonathan A, CORLESS, Christopher L, FLETCHER, Christopher D. M, ROBERTS, Peter J, HEINZ, Daniela

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PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors von Lee, William, Teckie, Sewit, Wiesner, Thomas, Ran, Leili, Prieto Granada, Carlos N, Lin, Mingyan, Zhu, Sinan, Cao, Zhen, Liang, Yupu, Sboner, Andrea, Tap, William D, Fletcher, Jonathan A, Huberman, Kety H, Qin, Li-Xuan, Viale, Agnes, Singer, Samuel, Zheng, Deyou, Berger, Michael F, Chen, Yu, Antonescu, Cristina R, Chi, Ping

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Mesenchymal tumors of the gastrointestinal tract with NTRK rearrangements: a clinicopathological, immunophenotypic, and molecular study of eight cases, emphasizing their distinctio... von Atiq, Mazen A., Davis, Jessica L., Hornick, Jason L., Dickson, Brendan C., Fletcher, Christopher D.M., Fletcher, Jonathan A., Folpe, Andrew L., Mariño-Enríquez, Adrián

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Correlation of Kinase Genotype and Clinical Outcome in the North American Intergroup Phase III Trial of Imatinib Mesylate for Treatment of Advanced Gastrointestinal Stromal Tumor:... von HEINRICH, Michael C, OWZAR, Kouros, BENJAMIN, Robert S, BRAMWELL, Vivien H, DEMETRI, George D, BERTAGNOLLI, Monica M, FLETCHER, Jonathan A, CORLESS, Christopher L, HOLLIS, Donna, BORDEN, Ernest C, FLETCHER, Christopher D. M, RYAN, Christopher W, VON MEHREN, Margaret, BLANKE, Charles D, RANKIN, Cathryn

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KIT Oncogenic Mutations: Biologic Insights, Therapeutic Advances, and Future Directions von Fletcher, Jonathan A

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Molecular Correlates of Imatinib Resistance in Gastrointestinal Stromal Tumors von HEINRICH, Michael C, CORLESS, Christopher L, MCDOUGALL, Karen, OU, Wen-Bin, CHEN, Chang-Jie, FLETCHER, Jonathan A, BLANKE, Charles D, DEMETRI, George D, JOENSUU, Heikki, ROBERTS, Peter J, EISENBERG, Burton L, VON MEHREN, Margaret, FLETCHER, Christopher D. M, SANDAU, Katrin

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What is New in Gastrointestinal Stromal Tumor? von Schaefer, Inga-Marie, Mariño-Enríquez, Adrián, Fletcher, Jonathan A

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BCOR Internal Tandem Duplication in High-grade Uterine Sarcomas von Mariño-Enriquez, Adrián, Lauria, Alexandra, Przybyl, Joanna, Ng, Tony L, Kowalewska, Magdalena, Debiec-Rychter, Maria, Ganesan, Raji, Sumathi, Vaiyapuri, George, Suzanne, McCluggage, W Glenn, Nucci, Marisa R, Lee, Cheng-Han, Fletcher, Jonathan A

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Profiling critical cancer gene mutations in clinical tumor samples von MacConaill, Laura E, Campbell, Catarina D, Kehoe, Sarah M, Bass, Adam J, Hatton, Charles, Niu, Lili, Davis, Matt, Yao, Keluo, Hanna, Megan, Mondal, Chandrani, Luongo, Lauren, Emery, Caroline M, Baker, Alissa C, Philips, Juliet, Goff, Deborah J, Fiorentino, Michelangelo, Rubin, Mark A, Polyak, Kornelia, Chan, Jennifer, Wang, Yuexiang, Fletcher, Jonathan A, Santagata, Sandro, Corso, Gianni, Roviello, Franco, Shivdasani, Ramesh, Kieran, Mark W, Ligon, Keith L, Stiles, Charles D, Hahn, William C, Meyerson, Matthew L, Garraway, Levi A

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The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma von Wu, Xinqi, Zhu, Meijun, Fletcher, Jonathan A, Giobbie-Hurder, Anita, Hodi, F Stephen

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Biology of Gastrointestinal Stromal Tumors von CORLESS, Christopher L, FLETCHER, Jonathan A, HEINRICH, Michael C

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Dystrophin is a tumor suppressor in human cancers with myogenic programs von Wang, Yuexiang, Marino-Enriquez, Adrian, Bennett, Richard R, Zhu, Meijun, Shen, Yiping, Eilers, Grant, Lee, Jen-Chieh, Henze, Joern, Fletcher, Benjamin S, Gu, Zhizhan, Fox, Edward A, Antonescu, Cristina R, Fletcher, Christopher D M, Guo, Xiangqian, Raut, Chandrajit P, Demetri, George D, van de Rijn, Matt, Ordog, Tamas, Kunkel, Louis M, Fletcher, Jonathan A

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Time‐resolved single‐electron wave‐packet detection von Kataoka, Masaya, Fletcher, Jonathan D., Johnson, Nathan

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Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients von Garner, Andrew P, Gozgit, Joseph M, Anjum, Rana, Vodala, Sadanand, Schrock, Alexa, Zhou, Tianjun, Serrano, Cesar, Eilers, Grant, Zhu, Meijun, Ketzer, Julia, Wardwell, Scott, Ning, Yaoyu, Song, Youngchul, Kohlmann, Anna, Wang, Frank, Clackson, Tim, Heinrich, Michael C, Fletcher, Jonathan A, Bauer, Sebastian, Rivera, Victor M

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Overcoming heterogenity in imatinib-resistant gastrointestinal stromal tumor von Serrano, César, Fletcher, Jonathan A.

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Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain von Grunewald, Susanne, Klug, Lillian R., Muhlenberg, Thomas, Lategahn, Jonas, Falkenhorst, Johanna, Town, Ajia, Ehrt, Christiane, Wardelmann, Eva, Hartmann, Wolfgang, Schildhaus, Hans-Ulrich, Treckmann, Juergen, Fletcher, Jonathan A., Jung, Sascha, Czodrowski, Paul, Miller, Stephen, Schmidt-Kittler, Oleg, Rauh, Daniel, Heinrich, Michael C., Bauer, Sebastian

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Gastrointestinal stromal tumors von Liegl-Atzwanger, Bernadette, Fletcher, Jonathan A., Fletcher, Christopher D. M.

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Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma von Edris, Badreddin, Weiskopf, Kipp, Volkmer, Anne K, Volkmer, Jens-Peter, Willingham, Stephen B, Contreras-Trujillo, Humberto, Liu, Jie, Majeti, Ravindra, West, Robert B, Fletcher, Jonathan A, Beck, Andrew H, Weissman, Irving L, van de Rijn, Matt

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SETDB1 tumour suppressor roles in near-haploid mesothelioma involve TP53 von Xu, Mengting, Tu, Yuqing, Bi, Wenhui, Lundberg, Meijun Z., Klooster, Isabella, Fletcher, Jonathan A., Ou, Wen-Bin

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