Discovery of N‑(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)‑5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)‑2H‑tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally... von Ruminski, Peter G, Massa, Mark, Strohbach, Joseph, Hanau, Cathleen E, Schmidt, Michelle, Scholten, Jeffrey A, Fletcher, Theresa R, Hamper, Bruce C, Carroll, Jeffery N, Shieh, Huey S, Caspers, Nicole, Collins, Brandon, Grapperhaus, Margaret, Palmquist, Katherine E, Collins, Joe, Baldus, John E, Hitchcock, Jeffrey, Kleine, H. Peter, Rogers, Michael D, McDonald, Joseph, Munie, Grace E, Messing, Dean M, Portolan, Silvia, Whiteley, Laurence O, Sunyer, Teresa, Schnute, Mark E

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Phase I Study of Azacitidine following Donor Lymphocyte Infusion for Relapsed Acute Myeloid Leukemia Post Allogeneic Stem Cell Transplantation von Ghobadi, Armin, MD, Choi, Jaebok, PhD, Fiala, Mark A., BS, CCRP, Fletcher, Theresa, MS, Liu, Jingxia, PhD, Eissenberg, Linda G., PhD, Abboud, Camille, MD, Cashen, Amanda, MD, Vij, Ravi, MD, Schroeder, Mark A., MD, Pusic, Iskra, MD, Stockerl-GoldsteinMD, Keith, MD, Jacoby, Meagan, MD, PhD, Uy, Geoffrey, MD, DiPersio, John, MD, PhD, Westervelt, Peter, MD, PhD

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Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia von Uy, Geoffrey L, Hsu, Yen-Michael S, Schmidt, Amy P, Stock, Wendy, Fletcher, Theresa R, Trinkaus, Kathryn M, Westervelt, Peter, DiPersio, John F, Link, Daniel C

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MMP-13 selective isonipecotamide α-sulfone hydroxamates von Kolodziej, Stephen A., Hockerman, Susan L., DeCrescenzo, Gary A., McDonald, Joseph J., Mischke, Debbie A., Munie, Grace E., Fletcher, Theresa R., Stehle, Nathan, Swearingen, Craig, Becker, Daniel P.

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Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis von SCHNUTE, Mark E, O'BRIEN, Patrick M, CARROLL, Jeffery N, PATT, William C, SHIEH, Huey S, COLLINS, Brandon, PAVLOVSKY, Alexander G, PALMQUIST, Katherine E, ASTON, Karl W, HITCHCOCK, Jeffrey, ROGERS, Michael D, MCDONALD, Joseph, NAHRA, Joe, JOHNSON, Adam R, MUNIE, Grace E, WITTWER, Arthur J, MAN, Chiu-Fai, SETTLE, Steven L, NEMIROVSKIY, Olga, VICKERY, Lillian E, AGAWAL, Arun, DYER, Richard D, SUNYER, Teresa, MORRIS, Mark, HOWARD ROARK, W, HANAU, Cathleen E, RUMINSKI, Peter G, SCHOLTEN, Jeffrey A, FLETCHER, Theresa R, HAMPER, Bruce C

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Orally bioavailable dual MMP-1/MMP-14 sparing, MMP-13 selective α-sulfone hydroxamates von Kolodziej, Stephen A., Hockerman, Susan L., Boehm, Terri L., Carroll, Jeffery N., DeCrescenzo, Gary A., McDonald, Joseph J., Mischke, Debbie A., Munie, Grace E., Fletcher, Theresa R., Rico, Joseph G., Stehle, Nathan W., Swearingen, Craig, Becker, Daniel P.

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Structure-based parallel medicinal chemistry approach to improve metabolic stability of benzopyran COX-2 inhibitors von Xing, Li, Hamper, Bruce C., Fletcher, Theresa R., Wendling, Jay M., Carter, Jeffery, Gierse, James K., Liao, Subo

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A novel class of apical sodium co-dependent bile acid transporter inhibitors: The 1,2-benzothiazepines von TOLLEFSON, Michael B, KOLODZIEJ, Stephen A, FLETCHER, Theresa R, VERNIER, William F, BEAUDRY, Judith A, KELLER, Bradley T, REITZ, David B

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A Study of Tbo-Filgrastim (Granix) to Disrupt the Bone Marrow Microenvironment in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation von Jacoby, Meagan, Bera, Reetom, Fletcher, Theresa, Fiala, Mark A., Trinkaus, Kathryn, DiPersio, John F., Stockerl-Goldstein, Keith E., Schroeder, Mark A., Link, Daniel C., Vij, Ravi

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Selinexor in Combination with Cladribine, Cytarabine and G-CSF for Relapsed or Refractory AML von Uy, Geoffrey L., Rettig, Michael P, Fletcher, Theresa, Riedell, Peter A, Stockerl-Goldstein, Keith E., Ghobadi, Armin, Jacoby, Meagan, Cashen, Amanda F., Romee, Rizwan, Pusic, Iskra, Abboud, Camille N., Schroeder, Mark A., Vij, Ravi, Westervelt, Peter, DiPersio, John F

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Phase II Study of Propylene Glycol-Free Melphalan (Evomela) Combined with Carmustine, Etoposide, and Cytarabine (BEAM) for Myeloablative Conditioning in Lymphoma Patients Undergoin... von Cashen, Amanda F., Gosch, Kendall, Fletcher, Theresa, Ceriotti, Connie, Ghobadi, Armin, Vij, Ravi, Stockerl-Goldstein, Keith, Dipersio, John F, Abboud, Camille N

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Phase II Study of Propylene Glycol-Free Melphalan (Evomela) Combined with Carmustine, Etoposide, and Cytarabine (BEAM) for Myeloablative Conditioning in Lymphoma Patients Undergoin... von Cashen, Amanda, MD, Gosch, Kendall, BA, Fletcher, Theresa, MS, Ceriotti, Connie, RN BSN, Ghobadi, Armin, MD, Vij, Ravi, MD, Stockerl-Goldstein, Keith, MD, DiPersio, John F., MD, PhD, Abboud, Camille, MD

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Phase I Study of Brentuximab Vedotin for the Prevention of Acute GvHD after Unrelated Allogeneic Stem Cell Transplantation von Schroeder, Mark A., MD, Rettig, Michael P., PhD, Willey, Sarah, Fletcher, Theresa, MS, Meier, Stephanie, Wang, Tzu-Fei, MD, Trinkaus, Kathryn, Ph.D, Romee, Rizwan, MD, Ghobadi, Armin, MD, Pusic, Iskra, MD, Abboud, Camille, MD, Stockerl-Goldstein, Keith, MD, Uy, Geoffrey L., MD, Vij, Ravi, MD, Westervelt, Peter, MD, PhD, DiPersio, John F., MD, PhD

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A Study of High Dose Lenalidomide Induction and Low Dose Lenalidomide Maintenance for Patients with Hypomethylating Agent Refractory MDS von Cherian, Mathew A., Tibes, Raoul, Fletcher, Theresa, Fiala, Mark A., Uy, Geoffrey L., Westervelt, Peter, Stockerl-Goldstein, Keith E., Jacoby, Meagan, Cashen, Amanda F., DiPersio, John F., Vij, Ravi

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A Phase I Study of Carfilzomib for Relapsed or Refractory Acute Myeloid and Acute Lymphoblastic Leukemia von Wartman, Lukas D., Fiala, Mark A., Hawkins, Emily, Fletcher, Theresa, Allen, Melissa, Cashen, Amanda F., DiPersio, John F., Jacoby, Meagan, Stockerl-Goldstein, Keith E., Pusic, Iskra, Uy, Geoffrey L., Westervelt, Peter, Vij, Ravi

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Discovery of N -(4-Fluoro-3-methoxybenzyl)-6-(2-(((2 S ,5 R )-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2 H -tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and... von Ruminski, Peter G., Massa, Mark, Strohbach, Joseph, Hanau, Cathleen E., Schmidt, Michelle, Scholten, Jeffrey A., Fletcher, Theresa R., Hamper, Bruce C., Carroll, Jeffery N., Shieh, Huey S., Caspers, Nicole, Collins, Brandon, Grapperhaus, Margaret, Palmquist, Katherine E., Collins, Joe, Baldus, John E., Hitchcock, Jeffrey, Kleine, H. Peter, Rogers, Michael D., McDonald, Joseph, Munie, Grace E., Messing, Dean M., Portolan, Silvia, Whiteley, Laurence O., Sunyer, Teresa, Schnute, Mark E.

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A Phase II Study Of V-BEAM (Bortezomib, Carmustine, Etoposide, Cytarabine, and Melphalan) As Conditioning Regimen Prior To Second Autologous Stem Cell Transplantation For Multiple... von Wang, Tzu-Fei, Fiala, Mark A., Wu, Ningying, Fletcher, Theresa, Abboud, Camille N., Cashen, Amanda F., Dipersio, John F., Uy, Geoffrey L., Westervelt, Peter, Stockerl-Goldstein, Keith E., Vij, Ravi

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Discovery of Potent, Nonsystemic Apical Sodium-Codependent Bile Acid Transporter Inhibitors (Part 2) von Huang, Horng-Chih, Tremont, Samuel J, Lee, Len F, Keller, Bradley T, Carpenter, Andrew J, Wang, Ching-Cheng, Banerjee, Shyamal C, Both, Scott R, Fletcher, Theresa, Garland, Danny J, Huang, Wei, Jones, Claude, Koeller, Kevin J, Kolodziej, Steve A, Li, James, Manning, Robert E, Mahoney, Matthew W, Miller, Raymond E, Mischke, Deborah A, Rath, Nigam P, Reinhard, Emily J, Tollefson, Michael B, Vernier, William F, Wagner, Grace M, Rapp, Steve R, Beaudry, Judy, Glenn, Kevin, Regina, Karen, Schuh, Joe R, Smith, Mark E, Trivedi, Jay S, Reitz, David B

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Phase II Study of Propylene Glycol–Free Melphalan Combined with Carmustine, Etoposide, and Cytarabine for Myeloablative Conditioning in Lymphoma Patients Undergoing Autologous Stem... von Cashen, Amanda F, Fletcher, Theresa, Ceriotti, Connie, Gao, Feng, Ghobadi, Armin, Vij, Ravi, Stockerl-Goldstein, Keith, DiPersio, John, Abboud, Camille

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Discovery of (pyridin-4-yl)-2 H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis von Schnute, Mark E., O’Brien, Patrick M., Nahra, Joe, Morris, Mark, Howard Roark, W., Hanau, Cathleen E., Ruminski, Peter G., Scholten, Jeffrey A., Fletcher, Theresa R., Hamper, Bruce C., Carroll, Jeffery N., Patt, William C., Shieh, Huey S., Collins, Brandon, Pavlovsky, Alexander G., Palmquist, Katherine E., Aston, Karl W., Hitchcock, Jeffrey, Rogers, Michael D., McDonald, Joseph, Johnson, Adam R., Munie, Grace E., Wittwer, Arthur J., Man, Chiu-Fai, Settle, Steven L., Nemirovskiy, Olga, Vickery, Lillian E., Agawal, Arun, Dyer, Richard D., Sunyer, Teresa

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