Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition von Hanssen, Kimberley M., Haber, Michelle, Fletcher, Jamie I.

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ABC transporters in cancer: more than just drug efflux pumps von Fletcher, Jamie I., Haber, Michelle, Henderson, Michelle J., Norris, Murray D.

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A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers von Jung, MoonSun, Russell, Amanda J, Liu, Bing, George, Joshy, Liu, Pei Yan, Liu, Tao, DeFazio, Anna, Bowtell, David D L, Oberthuer, André, London, Wendy B, Fletcher, Jamie I, Haber, Michelle, Norris, Murray D, Henderson, Michelle J

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The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression von Tee, Andrew E, Liu, Bing, Song, Renhua, Li, Jinyan, Pasquier, Eddy, Cheung, Belamy B, Jiang, Cizhong, Marshall, Glenn M, Haber, Michelle, Norris, Murray D, Fletcher, Jamie I, Dinger, Marcel E, Liu, Tao

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The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation von Nelson, Christopher B., Rogers, Samuel, Roychoudhury, Kaushik, Tan, Yaw Sing, Atkinson, Caroline J., Sobinoff, Alexander P., Tomlinson, Christopher G., Hsu, Anton, Lu, Robert, Dray, Eloise, Haber, Michelle, Fletcher, Jamie I., Cesare, Anthony J., Hegde, Rashmi S., Pickett, Hilda A.

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CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma von Fordham, Ashleigh M., Xie, Jinhan, Gifford, Andrew J., Wadham, Carol, Morgan, Lisa T., Mould, Emily V. A., Fadia, Mitali, Zhai, Lei, Massudi, Hassina, Ali, Zara S., Marshall, Glenn M., Lukeis, Robyn E., Fletcher, Jamie I., MacKenzie, Karen L., Trahair, Toby N.

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Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1 von Kvansakul, Marc, Wei, Andrew H, Fletcher, Jamie I, Willis, Simon N, Chen, Lin, Roberts, Andrew W, Huang, David C S, Colman, Peter M

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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax von Fletcher, Jamie I, Meusburger, Sarina, Hawkins, Christine J, Riglar, David T, Lee, Erinna F, Fairlie, W. Douglas, Huang, David C.S, Adams, Jerry M

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ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux von Henderson, Michelle J., Haber, Michelle, Porro, Antonio, Munoz, Marcia A., Iraci, Nunzio, Xue, Chengyuan, Murray, Jayne, Flemming, Claudia L., Smith, Janice, Fletcher, Jamie I., Gherardi, Samuele, Kwek, Chin-Kiat, Russell, Amanda J., Valli, Emanuele, London, Wendy B., Buxton, Allen B., Ashton, Lesley J., Sartorelli, Alan C., Cohn, Susan L., Schwab, Manfred, Marshall, Glenn M., Perini, Giovanni, Norris, Murray D.

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MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin von O'Brien, Rosemary, Tran, Sieu L, Maritz, Michelle F, Liu, Bing, Kong, Cheng Fei, Purgato, Stefania, Yang, Chen, Murray, Jayne, Russell, Amanda J, Flemming, Claudia L, von Jonquieres, Georg, Pickett, Hilda A, London, Wendy B, Haber, Michelle, Gunaratne, Preethi H, Norris, Murray D, Perini, Giovanni, Fletcher, Jamie I, MacKenzie, Karen L

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High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4) von Cheung, Leanna, Flemming, Claudia L., Watt, Fujiko, Masada, Nanako, Yu, Denise M.T., Huynh, Tony, Conseil, Gwenaëlle, Tivnan, Amanda, Polinsky, Alexander, Gudkov, Andrei V., Munoz, Marcia A., Vishvanath, Anasuya, Cooper, Dermot M.F., Henderson, Michelle J., Cole, Susan P.C., Fletcher, Jamie I., Haber, Michelle, Norris, Murray D.

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Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen von Cheung, Leanna, Yu, Denise M.T., Neiron, Zillan, Failes, Tim W., Arndt, Greg M., Fletcher, Jamie I.

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ABC transporters as mediators of drug resistance and contributors to cancer cell biology von Fletcher, Jamie I, Williams, Rebekka T, Henderson, Michelle J, Norris, Murray D, Haber, Michelle

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Controlling the cell death mediators Bax and Bak: puzzles and conundrums von Fletcher, Jamie I., Huang, David C.S.

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Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors von Grohmann, Christoph, Walker, Francesca, Devlin, Mark, Luo, Meng-Xiao, Chüeh, Anderly C., Doherty, Judy, Vaillant, François, Ho, Gwo-Yaw, Wakefield, Matthew J., Weeden, Clare E., Kamili, Alvin, Murray, Jayne, Po’uha, Sela T., Weinstock, Janet, Kane, Serena R., Faux, Maree C., Broekhuizen, Esmee, Zheng, Ye, Shield-Artin, Kristy, Kershaw, Nadia J., Tan, Chin Wee, Witchard, Helen M., Ebert, Gregor, Charman, Susan A., Street, Ian, Kavallaris, Maria, Haber, Michelle, Fletcher, Jamie I., Asselin-Labat, Marie-Liesse, Scott, Clare L., Visvader, Jane E., Lindeman, Geoffrey J., Watson, Keith G., Burgess, Antony W., Lessene, Guillaume

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Generation of Orthotopic and Subcutaneous Patient-Derived Xenograft Models from Diverse Clinical Tissue Samples of Pediatric Extracranial Solid Tumors von Hanssen, Kimberley M., Fletcher, Jamie I., Kamili, Alvin

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Too many targets, not enough patients: rethinking neuroblastoma clinical trials von Fletcher, Jamie I., Ziegler, David S., Trahair, Toby N., Marshall, Glenn M., Haber, Michelle, Norris, Murray D.

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Mouse models of high-risk neuroblastoma von Kamili, Alvin, Atkinson, Caroline, Trahair, Toby N., Fletcher, Jamie I.

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Quantification of vincristine and tariquidar by liquid chromatography‐tandem mass spectrometry in mouse whole blood using volumetric absorptive microsampling for pharmacokinetic ap... von Rosser, Sebastian P. A., Atkinson, Caroline, Nath, Christa E., Fletcher, Jamie I.

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins von Willis, Simon N, Chen, Lin, Dewson, Grant, Wei, Andrew, Naik, Edwina, Fletcher, Jamie I, Adams, Jerry M, Huang, David C S

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