Dasatinib (BMS-354825) Pharmacokinetics and Pharmacodynamic Biomarkers in Animal Models Predict Optimal Clinical Exposure von LUO, Feng R, ZHENG YANG, WEN, Mei-Li, KRAMER, Robert, BLACKWOOD-CHIRCHIR, Anne, LEE, Francis Y, CAMUSO, Amy, SMYKLA, Richard, MCGLINCHEY, Kelly, FAGER, Krista, FLEFLEH, Christine, CASTANEDA, Stephen, INIGO, Ivan, KAN, David

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Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression level... von Wild, Robert, Fager, Krista, Flefleh, Christine, Kan, David, Inigo, Ivan, Castaneda, Stephen, Luo, Feng Roger, Camuso, Amy, McGlinchey, Kelly, Rose, William C

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Chronotherapy and Chronotoxicity of the Cyclooxygenase-2 Inhibitor, Celecoxib, in Athymic Mice Bearing Human Breast Cancer Xenografts von BLUMENTHAL, Rosalyn D, WASKEWICH, Chris, GOLDENBERG, David M, LEW, Walter, FLEFLEH, Christine, BURTON, Jack

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Prediction of Active Drug Plasma Concentrations Achieved in Cancer Patients by Pharmacodynamic Biomarkers Identified from the Geo Human Colon Carcinoma Xenograft Model von LUO, Feng R, ZHENG YANG, WONG, Tai W, KRAMER, Robert A, WILD, Robert, LEE, Francis Y, HUIJIN DONG, CAMUSO, Amy, MCGLINCHEY, Kelly, FAGER, Krista, FLEFLEH, Christine, KAN, David, INIGO, Ivan, CASTANEDA, Stephen

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Dasatinib (BMS-354825) Overcomes Multiple Mechanisms of Imatinib Resistance in Chronic Myeloid Leukemia (CML) von Lee, Francis Y., Wen, Mei-Li, Bhide, Rajeev, Camuso, Amy, Castenada, Stephen, Fager, Krista, Flefleh, Christine, Inigo, Ivan, Kan, David, Luo, Roger, McGlinchey, Kelly, Smykla, Richard, Wild, Robert, Borzilleri, Robert, Lombardo, Louis

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Quiescent Chronic Myelogenous Leukemia (CML) Cells Are Resistant to BCR-ABL Inhibitors but Preferentially Sensitive to BMS-214662, a Farnesyltransferase Inhibitor (FTI) with Unique... von Lee, Francis Y., Wen, Mei-Li, Camuso, Amy, Castenada, Stephen, Fager, Krista, Flefleh, Christine, Inigo, Ivan, Luo, Roger, Kan, David, Manne, Veeraswamy, McGlinchey, Kelly, Smykla, Richard, Weinmann, Roberto, Kramer, Robert

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BMS-354825, a Dual SRC/ABL Kinase Inhibitor, Displays Potent Anti-Tumor Activity in a Model of Intracranial CML Growth von Wild, Robert, Castaneda, Stephen, Flefleh, Christine, Fager, Krista, Inigo, Ivan, Kan, David, Smykla, Richard, Camuso, Amy, McGlinchey, Kelly, Wen, Mei-Li, Luo, Feng Roger, Borzilleri, Robert, Lombardo, Louis, Kramer, Robert, Lee, Francis Y.

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Pharmacokinetics- and Pharmacodynamics-Guided Optimization of the Dose and Treatment Schedule for the Dual SRC/ABL Inhibitor BMS-354825 von Luo, Feng Roger, Yang, Zheng, Camuso, Amy, Smykla, Richard, Castenada, Stephen, Flefleh, Christine, Fager, Krista, Inigo, Ivan, Kan, David, McGlinchey, Kelly, Wen, Mei-Li, Wild, Robert, Borzilleri, Robert, Lombardo, Louis, Kramer, Robert, Lee, Francis Y.

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