The Conserved Misshapen-Warts-Yorkie Pathway Acts in Enteroblasts to Regulate Intestinal Stem Cells in Drosophila von Li, Qi, Li, Shuangxi, Mana-Capelli, Sebastian, Roth Flach, Rachel J., Danai, Laura V., Amcheslavsky, Alla, Nie, Yingchao, Kaneko, Satoshi, Yao, Xiaohao, Chen, Xiaochu, Cotton, Jennifer L., Mao, Junhao, McCollum, Dannel, Jiang, Jin, Czech, Michael P., Xu, Lan, Ip, Y. Tony

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IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis von Negrin, Kimberly A, Roth Flach, Rachel J, DiStefano, Marina T, Matevossian, Anouch, Friedline, Randall H, Jung, DaeYoung, Kim, Jason K, Czech, Michael P

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Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition von Roth Flach, Rachel J, Su, Chunyan, Bollinger, Eliza, Cortes, Christian, Robertson, Andrew W, Opsahl, Alan C, Coskran, Timothy M, Maresca, Kevin P, Keliher, Edmund J, Yates, Phillip D, Kim, Albert M, Kalgutkar, Amit S, Buckbinder, Leonard

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Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis von Roth Flach, Rachel J., Skoura, Athanasia, Matevossian, Anouch, Danai, Laura V., Zheng, Wei, Cortes, Christian, Bhattacharya, Samit K., Aouadi, Myriam, Hagan, Nana, Yawe, Joseph C., Vangala, Pranitha, Menendez, Lorena Garcia, Cooper, Marcus P., Fitzgibbons, Timothy P., Buckbinder, Leonard, Czech, Michael P.

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An assessment of thermoneutral housing conditions on murine cardiometabolic function von Chen, Xian, Bollinger, Eliza, Cunio, Teresa, Damilano, Federico, Stansfield, John C, Pinkus, Cynthia A, Kreuser, Steven, Hirenallur-Shanthappa, Dinesh, Roth Flach, Rachel J

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Nonsteroidal Anti-inflammatory Drugs in Ophthalmology von Kim, Stephen J., MD, Flach, Allan J., MD, Jampol, Lee M., MD

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Hepatic Mitogen-Activated Protein Kinase Phosphatase 1 Selectively Regulates Glucose Metabolism and Energy Homeostasis von Lawan, Ahmed, Zhang, Lei, Gatzke, Florian, Min, Kisuk, Jurczak, Michael J., Al-Mutairi, Mashael, Richter, Patric, Camporez, Joao Paulo G., Couvillon, Anthony, Pesta, Dominik, Roth Flach, Rachel J., Shulman, Gerald I., Bennett, Anton M.

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Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels von Roth Flach, Rachel J., Bollinger, Eliza, Reyes, Allan R., Laforest, Brigitte, Kormos, Bethany L., Liu, Shenping, Reese, Matthew R., Martinez Alsina, Luis A., Buzon, Leanne, Zhang, Yuan, Bechle, Bruce, Rosado, Amy, Sahasrabudhe, Parag V., Knafels, John, Bhattacharya, Samit K., Omoto, Kiyoyuki, Stansfield, John C., Hurley, Liam D., Song, LouJin, Luo, Lina, Breitkopf, Susanne B., Monetti, Mara, Cunio, Teresa, Tierney, Brendan, Geoly, Frank J., Delmore, Jake, Siddall, C. Parker, Xue, Liang, Yip, Ka N., Kalgutkar, Amit S., Miller, Russell A., Zhang, Bei B., Filipski, Kevin J.

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Mixed meal tolerance testing highlights in diabetes altered branched-chain ketoacid metabolism and pathways associated with all-cause mortality von Mi, Michael Y., Whitlock, Mark, Shi, Xu, Farrell, Laurie A., Bhambhani, Victoria M., Quadir, Juweria, Blatnik, Matthew, Wald, Kyle P., Tierney, Brendan, Kim, Albert, Loudon, Peter, Chen, Zsu-Zsu, Correa, Adolfo, Gao, Yan, Carson, April P., Bertoni, Alain G., Roth Flach, Rachel J., Gerszten, Robert E.

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Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors von Liu, Shenping, Kormos, Bethany L., Knafels, John D., Sahasrabudhe, Parag V., Rosado, Amy, Sommese, Ruth F., Reyes, Allan R., Ward, Jessica, Roth Flach, Rachel J., Wang, Xiaochun, Buzon, Leanne M., Reese, Matthew R., Bhattacharya, Samit K., Omoto, Kiyoyuki, Filipski, Kevin J.

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NETs and traps delay wound healing in diabetes von Roth Flach, Rachel J, Czech, Michael P

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Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension von Song, LouJin, Chen, Xian, Swanson, Terri A, LaViolette, Brianna, Pang, Jincheng, Cunio, Teresa, Nagle, Michael W, Asano, Shoh, Hales, Katherine, Shipstone, Arun, Sobon, Hanna, Al-Harthy, Sabra D, Ahn, Youngwook, Kreuser, Steven, Robertson, Andrew, Ritenour, Casey, Voigt, Frank, Boucher, Magalie, Sun, Furong, Sessa, William C, Roth Flach, Rachel J

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BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice von Bollinger, Eliza, Peloquin, Matthew, Libera, Jenna, Albuquerque, Bina, Pashos, Evanthia, Shipstone, Arun, Hadjipanayis, Angela, Sun, Zhongyuan, Xing, Gang, Clasquin, Michelle, Stansfield, John C., Tierney, Brendan, Gernhardt, Steven, Siddall, C. Parker, Greizer, Timothy, Geoly, Frank J., Vargas, Sarah R., Gao, Lily C., Williams, George, Marshall, Mackenzie, Rosado, Amy, Steppan, Claire, Filipski, Kevin J., Zhang, Bei B., Miller, Russell A., Roth Flach, Rachel J.

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The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis von DiStefano, Marina T., Danai, Laura V., Roth Flach, Rachel J., Chawla, Anil, Pedersen, David J., Guilherme, Adilson, Czech, Michael P.

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Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948 von Filipski, Kevin J, Martinez-Alsina, Luis A, Reese, Matthew R, Evrard, Edelweiss, Buzon, Leanne M, Cameron, Kimberly O, Zhang, Yuan, Coffman, Karen J, Bradow, James, Kormos, Bethany L, Liu, Shenping, Knafels, John D, Sahasrabudhe, Parag V, Chen, Jie, Kalgutkar, Amit S, Bessire, Andrew J, Orozco, Christine C, Balesano, Amanda, Cerny, Matthew A, Bollinger, Eliza, Reyes, Allan R, Laforest, Brigitte, Rosado, Amy, Williams, George, Marshall, Mackenzie, Tam Neale, Kelly, Chen, Xian, Hirenallur-Shanthappa, Dinesh, Stansfield, John C, Groarke, John, Qiu, Ruolun, Karas, Spinel, Roth Flach, Rachel J, Esler, William P

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Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion von Senol-Cosar, Ozlem, Flach, Rachel J. Roth, DiStefano, Marina, Chawla, Anil, Nicoloro, Sarah, Straubhaar, Juerg, Hardy, Olga T., Noh, Hye Lim, Kim, Jason K., Wabitsch, Martin, Scherer, Philipp E., Czech, Michael P.

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Targeting lymphatic function in cardiovascular-kidney-metabolic syndrome: preclinical methods to analyze lymphatic function and therapeutic opportunities von Fowler, Joseph Wayne M, Song, LouJin, Tam, Kelly, Roth Flach, Rachel J

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β3-Adrenergic Receptor Stimulation Induces E-Selectin-mediated Adipose Tissue Inflammation von Roth Flach, Rachel J., Matevossian, Anouch, Akie, Thomas E., Negrin, Kimberly A., Paul, Marina T., Czech, Michael P.

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Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension von Berger, Justin H., Shi, Yuji, Matsuura, Timothy R., Batmanov, Kirill, Chen, Xian, Tam, Kelly, Marshall, Mackenzie, Kue, Richard, Patel, Jiten, Taing, Renee, Callaway, Russell, Griffin, Joanna, Kovacs, Attila, Hirenallur-Shanthappa, Dinesh, Miller, Russell, Zhang, Bei B., Flach, Rachel J. Roth, Kelly, Daniel P.

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Loss of Mitogen-activated Protein Kinase Phosphatase-1 Protects from Hepatic Steatosis by Repression of Cell Death-inducing DNA Fragmentation Factor A (DFFA)-like Effector C (CIDEC... von Flach, Rachel J. Roth, Qin, Hui, Zhang, Lei, Bennett, Anton M.

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