Recombinant human soluble domain of CD39L3 and ticagrelor: cardioprotective effects in experimental myocardial infarction von Vilahur, Gemma, Radike, Monika, Sutelman, Pablo, Ben-Aicha, Soumaya, Gutiérrez, Manuel, Casaní, Laura, Hovdal, Daniel, Ongstad, Emily L, Gabrielsen, Anders, Hidalgo, Alberto, Fjellström, Ola, Carlsson, Leif, Badimon, Lina

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The greater impact of PNPLA3 polymorphism on liver-related events in Japanese non-alcoholic fatty liver disease patients: A multicentre cohort study von Seko, Yuya, Yamaguchi, Kanji, Shima, Toshihide, Iwaki, Michihiro, Takahashi, Hirokazu, Kawanaka, Miwa, Tanaka, Saiyu, Mitsumoto, Yasuhide, Yoneda, Masato, Nakajima, Atsushi, Fjellström, Ola, Blau, Jenny E, Carlsson, Björn, Okanoue, Takeshi, Itoh, Yoshito

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The Structure of Murine N 1‑Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism von Sjögren, Tove, Wassvik, Carola M, Snijder, Arjan, Aagaard, Anna, Kumanomidou, Taichi, Barlind, Louise, Kaminski, Tim P, Kashima, Akiko, Yokota, Takehiro, Fjellström, Ola

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Safety, Tolerability, and Pharmacodynamics of AZD3366 (Optimized Human CD39L3 Apyrase) Alone and in Combination With Ticagrelor and Acetylsalicylic Acid: A Phase 1, Randomized, Pla... von Kardassis, Dimitris, Egnell, Ann-Charlotte, Åstrand, Magnus, Daniels, Samuel J, Whatling, Carl, Fjellström, Ola, Gabrielsen, Anders

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Small molecule modulators of PCSK9 – A literature and patent overview von Pettersen, Daniel, Fjellström, Ola

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Identification of novel GPR81 agonist lead series for target biology evaluation von Davidsson, Öjvind, Nilsson, Kristina, Brånalt, Jonas, Andersson, Terese, Berggren, Kristina, Chen, Yantao, Fjellström, Ola, Gradén, Henrik, Gustafsson, Linda, Hermansson, Nils-Olov, Jansen, Frank, Johannesson, Petra, Ohlsson, Bengt, Tyrchan, Christian, Wellner, Annika, Wellner, Eric, Ölwegård-Halvarsson, Maria

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Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 That Accelerates the Transition into the Latent Conformation von Fjellström, Ola, Deinum, Johanna, Sjögren, Tove, Johansson, Carina, Geschwindner, Stefan, Nerme, Viveca, Legnehed, Anne, McPheat, Jane, Olsson, Karolina, Bodin, Cristian, Paunovic, Amalia, Gustafsson, David

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Synthesis and Pharmacological Properties of Silicon-Containing GPR81 and GPR109A Agonists von Geyer, Marcel, Baus, Johannes A., Fjellström, Ola, Wellner, Eric, Gustafsson, Linda, Tacke, Reinhold

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Involvement of the metabolic sensor GPR81 in cardiovascular control von Wallenius, Kristina, Thalén, Pia, Björkman, Jan-Arne, Johannesson, Petra, Wiseman, John, Böttcher, Gerhard, Fjellström, Ola, Oakes, Nicholas D

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Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure von Granberg, Kenneth L., Sakamaki, Shigeki, Larsson, Niklas, Bergström, Fredrik, Fuchigami, Ryuichi, Niwa, Yasuki, Ryberg, Erik, Backmark, Anna, Kato, Harutoshi, Miyazaki, Shiki, Iguchi, Kaori, Sakamoto, Toshiaki, Persson, Mikael, Idei, Akiko, Prieto Garcia, Luna, Villar, Inmaculada C., Gradén, Henrik, Bergonzini, Giulia, Arvidsson, Torbjörn, Fujita, Takuya, Althage, Magnus, Ulander, Johan, Kimura, Junpei, Yoneda, Hikaru, Fjellström, Ola, Mochida, Hideki, Lal, Mark

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Recombinant Apyrase (AZD3366) Against Myocardial Reperfusion Injury von Birnbaum, Yochai, Ye, Regina, Chen, Huan, Carlsson, Leif, Whatling, Carl, Fjellström, Ola, Ryberg, Erik, Ye, Yumei

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Potent Fibrinolysis Inhibitor Discovered by Shape and Electrostatic Complementarity to the Drug Tranexamic Acid von Boström, Jonas, Grant, J. Andrew, Fjellström, Ola, Thelin, Anders, Gustafsson, David

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Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists von Almquist, Joachim, Hovdal, Daniel, Ahlström, Christine, Fjellström, Ola, Gennemark, Peter, Sundqvist, Monika

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Patatin-like phospholipase domain-containing 3 (PNPLA3) risk allele increases rate of progression to end-stage liver disease outcomes and decreases survival rate over time irrespec... von Armisen, Javier, Blau, Jenny, Fernando, Nellie, Hun, Monika, Rauschecker, Mitra, Wernevik, Linda, Fjellstrom, Ola, Paul, Dirk, Carlsson, Björn, Svangård, Nils

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THU-416 - Patatin-like phospholipase domain-containing 3 (PNPLA3) risk allele increases rate of progression to end-stage liver disease outcomes and decreases survival rate over tim... von Armisen, Javier, Blau, Jenny, Fernando, Nellie, Hun, Monika, Rauschecker, Mitra, Wernevik, Linda, Fjellstrom, Ola, Paul, Dirk, Carlsson, Björn, Svangård, Nils

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Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design von Fjellström, Ola, Akkaya, Sibel, Beisel, Hans-Georg, Eriksson, Per-Olof, Erixon, Karl, Gustafsson, David, Jurva, Ulrik, Kang, Daiwu, Karis, David, Knecht, Wolfgang, Nerme, Viveca, Nilsson, Ingemar, Olsson, Thomas, Redzic, Alma, Roth, Robert, Sandmark, Jenny, Tigerström, Anna, Öster, Linda

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Abstract 13097: Safety, Pharmacokinetics, and Pharmacodynamics of AZD3366 Alone and in Combination With Aspirin and Ticagrelor in Healthy Subjects von Kardassis, Dimitris, Egnell, Ann-Charlotte, Åstrand, Magnus, Daniels, Samuel J, Frickleton, Celeste, Whatling, Carl, Fjellstrom, Ola, Gabrielsen, Anders

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Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function von Sandmark, Jenny, Tigerström, Anna, Akerud, Tomas, Althage, Magnus, Antonsson, Thomas, Blaho, Stefan, Bodin, Cristian, Boström, Jonas, Chen, Yantao, Dahlén, Anders, Eriksson, Per-Olof, Evertsson, Emma, Fex, Tomas, Fjellström, Ola, Gustafsson, David, Herslöf, Margareta, Hicks, Ryan, Jarkvist, Emelie, Johansson, Carina, Kalies, Inge, Karlsson Svalstedt, Birgitta, Kartberg, Fredrik, Legnehed, Anne, Martinsson, Sofia, Moberg, Andreas, Ridderström, Marianne, Rosengren, Birgitta, Sabirsh, Alan, Thelin, Anders, Vinblad, Johanna, Wellner, Annika U., Xu, Bingze, Östlund-Lindqvist, Ann-Margret, Knecht, Wolfgang

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Hepatic patatin‐like phospholipase domain‐containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans von Ericson, Elke, Bergenholm, Linnéa, Andréasson, Anne‐Christine, Dix, Carly I., Knöchel, Jane, Hansson, Sara F., Lee, Richard, Schumi, Jennifer, Antonsson, Madeleine, Fjellström, Ola, Nasr, Patrik, Liljeblad, Mathias, Carlsson, Björn, Kechagias, Stergios, Lindén, Daniel, Ekstedt, Mattias

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Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents von Fjellström, Ola, Larsson, Niklas, Yasuda, Shin-Ichiro, Tsuchida, Takuma, Oguma, Takahiro, Marley, Anna, Wennberg-Huldt, Charlotte, Hovdal, Daniel, Fukuda, Hajime, Yoneyama, Yukimi, Sasaki, Kazuyo, Johansson, Anders, Lundqvist, Sara, Brengdahl, Johan, Isaacs, Richard J, Brown, Daniel, Geschwindner, Stefan, Benthem, Lambertus, Priest, Claire, Turnbull, Andrew

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