A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome von Wiseman, Frances K., Al-Janabi, Tamara, Hardy, John, Karmiloff-Smith, Annette, Nizetic, Dean, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Strydom, André

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Is SOD1 loss of function involved in amyotrophic lateral sclerosis? von SACCON, Rachele A, BUNTON-STASYSHYN, Rosie K. A, FISHER, Elizabeth M. C, FRATTA, Pietro

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Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia von Fratta, Pietro, Poulter, Mark, Lashley, Tammaryn, Rohrer, Jonathan D., Polke, James M., Beck, Jon, Ryan, Natalie, Hensman, Davina, Mizielinska, Sarah, Waite, Adrian J., Lai, Mang-Ching, Gendron, Tania F., Petrucelli, Leonard, Fisher, Elizabeth M. C., Revesz, Tamas, Warren, Jason D., Collinge, John, Isaacs, Adrian M., Mead, Simon

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SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments von Joyce, Peter I., Fratta, Pietro, Fisher, Elizabeth M. C., Acevedo-Arozena, Abraham

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Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome von Cannavo, Claudia, Cleverley, Karen, Maduro, Cheryl, Mumford, Paige, Moulding, Dale, Fisher, Elizabeth M C, Wiseman, Frances K

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Correlation of clinical and molecular features in spinal bulbar muscular atrophy von Fratta, Pietro, Nirmalananthan, Niranjanan, Masset, Luc, Skorupinska, Iwona, Collins, Toby, Cortese, Andrea, Pemble, Sally, Malaspina, Andrea, Fisher, Elizabeth M.C, Greensmith, Linda, Hanna, Michael G

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Species-Specific Transcription in Mice Carrying Human Chromosome 21 von Wilson, Michael D, Barbosa-Morais, Nuno L, Schmidt, Dominic, Conboy, Caitlin M, Vanes, Lesley, Tybulewicz, Victor L.J, Fisher, Elizabeth M.C, Tavaré, Simon, Odom, Duncan T

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Genetic analysis of the cytoplasmic dynein subunit families von Pfister, K Kevin, Shah, Paresh R, Hummerich, Holger, Russ, Andreas, Cotton, James, Annuar, Azlina Ahmad, King, Stephen M, Fisher, Elizabeth M C

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Down syndrome—recent progress and future prospects von Wiseman, Frances K., Alford, Kate A., Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.

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Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration von Watson-Scales, Sheona, Kalmar, Bernadett, Lana-Elola, Eva, Gibbins, Dorota, La Russa, Federica, Wiseman, Frances, Williamson, Matthew, Saccon, Rachele, Slender, Amy, Olerinyova, Anna, Mahmood, Radma, Nye, Emma, Cater, Heather, Wells, Sara, Yu, Y Eugene, Bennett, David L H, Greensmith, Linda, Fisher, Elizabeth M C, Tybulewicz, Victor L J

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Aneuploid Mouse Strain Carrying Human Chromosome 21 with Down Syndrome Phenotypes von O'Doherty, Aideen, Ruf, Sandra, Mulligan, Claire, Hildreth, Victoria, Errington, Mick L, Cooke, Sam, Sesay, Abdul, Modino, Sonie, Vanes, Lesley, Hernandez, Diana, Linehan, Jacqueline M, Sharpe, Paul T, Brandner, Sebastian, Bliss, Timothy V. P, Henderson, Deborah J, Nizetic, Dean, Tybulewicz, Victor L. J, Fisher, Elizabeth M. C

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Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations von Urwin, Hazel, Authier, Astrid, Nielsen, Jorgen E., Metcalf, Daniel, Powell, Caroline, Froud, Kristina, Malcolm, Denise S., Holm, Ida, Johannsen, Peter, Brown, Jeremy, Fisher, Elizabeth M.C., van der Zee, Julie, Bruyland, Marc, Van Broeckhoven, Christine, Collinge, John, Brandner, Sebastian, Futter, Clare, Isaacs, Adrian M.

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Humanising the mouse genome piece by piece von Zhu, Fei, Nair, Remya R., Fisher, Elizabeth M. C., Cunningham, Thomas J.

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Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice von GHAZI-NOORI, Shabnam, FROUD, Kristina E, ASANTE, Emmanuel A, BRANDNER, Sebastian, COLLINGE, John, ISAACS, Adrian M, MIZIELINSKA, Sarah, POWELL, Caroline, SMIDAK, Michelle, DE MARCO, Mar Fernandez, O'MALLEY, Catherine, FARMER, Michael, PARKINSON, Nick, FISHER, Elizabeth M. C

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point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice von Becker, Esther B.E, Oliver, Peter L, Glitsch, Maike D, Banks, Gareth T, Achilli, Francesca, Hardy, Andrea, Nolan, Patrick M, Fisher, Elizabeth M.C, Davies, Kay E

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Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome von Gribble, Susan M, Wiseman, Frances K, Clayton, Stephen, Prigmore, Elena, Langley, Elizabeth, Yang, Fengtang, Maguire, Sean, Fu, Beiyuan, Rajan, Diana, Sheppard, Olivia, Scott, Carol, Hauser, Heidi, Stephens, Philip J, Stebbings, Lucy A, Ng, Bee Ling, Fitzgerald, Tomas, Quail, Michael A, Banerjee, Ruby, Rothkamm, Kai, Tybulewicz, Victor L J, Fisher, Elizabeth M C, Carter, Nigel P

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Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years von Hithersay, Rosalyn, Startin, Carla M, Hamburg, Sarah, Mok, Kin Y, Hardy, John, Fisher, Elizabeth M. C, Tybulewicz, Victor L. J, Nizetic, Dean, Strydom, André

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Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B von Wu, Yixing, Mumford, Paige, Noy, Suzanna, Cleverley, Karen, Mrzyglod, Alicja, Luo, Dinghao, van Dalen, Floris, Verdoes, Martijn, Fisher, Elizabeth M C, Wiseman, Frances K

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Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans von van de Leemput, Joyce, Chandran, Jayanth, Knight, Melanie A, Holtzclaw, Lynne A, Scholz, Sonja, Cookson, Mark R, Houlden, Henry, Gwinn-Hardy, Katrina, Fung, Hon-Chung, Lin, Xian, Hernandez, Dena, Simon-Sanchez, Javier, Wood, Nick W, Giunti, Paola, Rafferty, Ian, Hardy, John, Storey, Elsdon, Gardner, R J McKinlay, Forrest, Susan M, Fisher, Elizabeth M C, Russell, James T, Cai, Huaibin, Singleton, Andrew B

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Genomically humanized mice: technologies and promises von Devoy, Anny, Bunton-Stasyshyn, Rosie K. A., Tybulewicz, Victor L. J., Smith, Andrew J. H., Fisher, Elizabeth M. C.

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