Extended-Duration MK-8591-Eluting Implant as a Candidate for HIV Treatment and Prevention von Barrett, Stephanie E, Teller, Ryan S, Forster, Seth P, Li, Li, Mackey, Megan A, Skomski, Daniel, Yang, Zhen, Fillgrove, Kerry L, Doto, Gregory J, Wood, Sandra L, Lebron, Jose, Grobler, Jay A, Sanchez, Rosa I, Liu, Zhen, Lu, Bing, Niu, Tao, Sun, Li, Gindy, Marian E

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Islatravir Is Not Expected to Be a Victim or Perpetrator of Drug-Drug Interactions via Major Drug-Metabolizing Enzymes or Transporters von Bleasby, Kelly, Houle, Robert, Hafey, Michael, Lin, Meihong, Guo, Jingjing, Lu, Bing, Sanchez, Rosa I., Fillgrove, Kerry L.

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In Vitro Evaluation of the Drug Interaction Potential of Doravirine von Bleasby, Kelly, Fillgrove, Kerry L, Houle, Robert, Lu, Bing, Palamanda, Jairam, Newton, Deborah J, Lin, Meihong, Chan, Grace Hoyee, Sanchez, Rosa I

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Safety and Pharmacokinetics of Once-Daily Multiple-Dose Administration of Islatravir in Adults Without HIV von Matthews, Randolph P., Jackson Rudd, Deanne, Zhang, Saijuan, Fillgrove, Kerry L., Sterling, Laura M., Grobler, Jay A., Vargo, Ryan C., Stoch, S. Aubrey, Iwamoto, Marian

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Physiologically Based Pharmacokinetic Modeling of Doravirine and Its Major Metabolite to Support Dose Adjustment With Rifabutin von Yee, Ka Lai, Cabalu, Tamara D., Kuo, Yuhsin, Fillgrove, Kerry L., Liu, Yang, Triantafyllou, Ilias, McClain, Sasha, Dreyer, Daniel, Wenning, Larissa, Stoch, S. Aubrey, Iwamoto, Marian, Sanchez, Rosa I., Khalilieh, Sauzanne G.

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A Phase 1 Study to Evaluate the Drug Interaction Between Islatravir (MK-8591) and Doravirine in Adults Without HIV von Matthews, Randolph P., Jackson Rudd, Deanne, Fillgrove, Kerry L., Zhang, Saijuan, Tomek, Charles, Stoch, S. Aubrey, Iwamoto, Marian

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Fluorinated Isoindolinone-Based Glucosylceramide Synthase Inhibitors with Low Human Dose Projections von Loughran, H. Marie, Schirripa, Kathy M., Roecker, Anthony J., Breslin, Michael J., Tong, Ling, Fillgrove, Kerry L., Kuo, Yuhsin, Bleasby, Kelly, Collier, Hannah, Altman, Michael D., Ford, Melissa C., Newman, Justin A., Drolet, Robert E., Cosden, Mali, Jinn, Sarah, Flick, Rosemarie B., Liu, Xiaomei, Minnick, Christina, Watt, Marla L., Lemaire, Wei, Burlein, Christine, Adam, Gregory C., Austin, Lauren A., Marcus, Jacob N., Smith, Sean M., Fraley, Mark E.

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Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator von Rudd, Michael T., Manley, Peter J., Hanney, Barbara, Meng, Zhaoyang, Shu, Youheng, de Leon, Pablo, Frie, Jessica L., Han, Yongxin, Wai, Jenny Miu-Chun, Yang, Zhi-Qiang, Perkins, James J., Hurzy, Danielle M., Manikowski, Jesse J., Zhu, Hong, Bungard, Christopher J., Converso, Antonella, Meissner, Robert S., Cosden, Mali L., Hayashi, Ikuo, Ma, Lei, O’Brien, Julie, Uebele, Victor N., Schachter, Joel B., Bhandari, Neetesh, Ward, Gwendolyn J., Fillgrove, Kerry L., Lu, Bing, Liang, Yuexia, Dubost, David C., Puri, Vanita, Eddins, Donnie M., Vardigan, Joshua D., Drolet, Robert E., Kern, Jonathan T., Uslaner, Jason M.

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Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinic... von Layton, Mark E., Reif, Alexander J., Hartingh, Timothy J., Rodzinak, Kevin, Dudkin, Vadim, Wang, Cheng, Arrington, Ken, Kelly, Michael J., Garbaccio, Robert M., O’Brien, Julie A., Magliaro, Brian C., Uslaner, Jason M., Huszar, Sarah L., Fillgrove, Kerry L., Tang, Cuyue, Kuo, Yuhsin, Jacobson, Marlene A.

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Mechanistic Diversity of Fosfomycin Resistance in Pathogenic Microorganisms von Fillgrove, Kerry L, Pakhomova, Svetlana, Newcomer, Marcia E, Armstrong, Richard N

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Triclosan inhibits enoyl-reductase of type I fatty acid synthase in vitro and is cytotoxic to MCF-7 and SKBr-3 breast cancer cells von BINQIU LIU, YINGQIANG WANG, FILLGROVE, Kerry L, ANDERSON, Vernon E

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Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI von Pero, Joseph E, Rossi, Michael A, Kelly, Michael J, Lehman, Hannah D. G. F, Layton, Mark E, Garbaccio, Robert M, O’Brien, Julie A, Magliaro, Brian C, Uslaner, Jason M, Huszar, Sarah L, Fillgrove, Kerry L, Tang, Cuyue, Kuo, Yuhsin, Joyce, Leo A, Sherer, Edward C, Jacobson, Marlene A

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Orientation of Coenzyme A Substrates, Nicotinamide and Active Site Functional Groups in (Di)enoyl−coenzyme A Reductases von Fillgrove, Kerry L, Anderson, Vernon E

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Cloning, Expression, and Purification of the Functional 2,4-Dienoyl-CoA Reductase from Rat Liver Mitochondria von Fillgrove, Kerry L., Anderson, Vernon E., Mizugaki, Michinao

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Once-Weekly Oral Dosing of MK-8591 Protects Male Rhesus Macaques From Intrarectal Challenge With SHIV109CP3 von Markowitz, Martin, Gettie, Agegnehu, St. Bernard, Leslie, Andrews, Chasity D, Mohri, Hiroshi, Horowitz, Amir, Grasperge, Brooke F, Blanchard, James L, Niu, Tao, Sun, Li, Fillgrove, Kerry, Hazuda, Daria J, Grobler, Jay A

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