Evolution of Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors. From Concept to Clinic von Ferraris, Dana V

Volltext

The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type von Yuneva, Mariia O., Fan, Teresa W.M., Allen, Thaddeus D., Higashi, Richard M., Ferraris, Dana V., Tsukamoto, Takashi, Matés, José M., Alonso, Francisco J., Wang, Chunmei, Seo, Youngho, Chen, Xin, Bishop, J. Michael

Volltext

Catalytic, asymmetric alkylation of imines von Ferraris ∗, Dana

Volltext

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression von Grunewald, Matthew E, Chen, Yating, Kuny, Chad, Maejima, Takashi, Lease, Robert, Ferraris, Dana, Aikawa, Masanori, Sullivan, Christopher S, Perlman, Stanley, Fehr, Anthony R

Volltext

Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES) von Robinson, Mary M, McBryant, Steven J, Tsukamoto, Takashi, Rojas, Camilo, Ferraris, Dana V, Hamilton, Sean K, Hansen, Jeffrey C, Curthoys, Norman P

Volltext

Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1 von SELTZER, Meghan J, BENNETT, Bryson D, DANG, Chi V, RIGGINS, Gregory J, JOSHI, Avadhut D, PING GAO, THOMAS, Ajit G, FERRARIS, Dana V, TSUKAMOTO, Takashi, ROJAS, Camilo J, SLUSHER, Barbara S, RABINOWITZ, Joshua D

Volltext

Design, Synthesis, and Pharmacological Evaluation of Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl Sulfide 3 (BPTES) Analogs as Glutaminase Inhibitors von Shukla, Krupa, Ferraris, Dana V., Thomas, Ajit G., Stathis, Marigo, Duvall, Bridget, Delahanty, Greg, Alt, Jesse, Rais, Rana, Rojas, Camilo, Gao, Ping, Xiang, Yan, Dang, Chi V., Slusher, Barbara S., Tsukamoto, Takashi

Volltext

Analysis of the Mechanisms of Action of Naphthoquinone-Based Anti-Acute Myeloid Leukemia Chemotherapeutics von Lee, Michelle H, Lapidus, Rena G, Ferraris, Dana, Emadi, Ashkan

Volltext

D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II von Gori, Sadakatali S, Thomas, Ajit G, Pal, Arindom, Wiseman, Robyn, Ferraris, Dana V, Gao, Run-Duo, Wu, Ying, Alt, Jesse, Tsukamoto, Takashi, Slusher, Barbara S, Rais, Rana

Volltext

Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors von Thomas, Ajit G., Rojas, Camilo, Tanega, Cordelle, Shen, Min, Simeonov, Anton, Boxer, Matthew B., Auld, Douglas S., Ferraris, Dana V., Tsukamoto, Takashi, Slusher, Barbara S.

Volltext

Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors von Barinka, Cyril, Novakova, Zora, Hin, Niyada, Bím, Daniel, Ferraris, Dana V., Duvall, Bridget, Kabarriti, Gabriel, Tsukamoto, Reiji, Budesinsky, Milos, Motlova, Lucia, Rojas, Camilo, Slusher, Barbara S., Rokob, Tibor András, Rulíšek, Lubomír, Tsukamoto, Takashi

Volltext

Co-Administration of a D-Amino Acid Oxidase Inhibitor Potentiates the Efficacy of D-Serine in Attenuating Prepulse Inhibition Deficits After Administration of Dizocilpine von Hashimoto, Kenji, Fujita, Yuko, Horio, Mao, Kunitachi, Shinsui, Iyo, Masaomi, Ferraris, Dana, Tsukamoto, Takashi

Volltext

Accumulation of Free ADP-ribose from Mitochondria Mediates Oxidative Stress-induced Gating of TRPM2 Cation Channels von Perraud, Anne-Laure, Takanishi, Christina L., Shen, Betty, Kang, Shin, Smith, Megan K., Schmitz, Carsten, Knowles, Heather M., Ferraris, Dana, Li, Weixing, Zhang, Jie, Stoddard, Barry L., Scharenberg, Andrew M.

Volltext

An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors von O'Connor, Joseph J, Ferraris, Dana, Fehr, Anthony R

Volltext

Synthesis and Biological Evaluation of d-Amino Acid Oxidase Inhibitors von Ferraris, Dana, Duvall, Bridget, Ko, Yao-Sen, Thomas, Ajit G, Rojas, Camilo, Majer, Pavel, Hashimoto, Kenji, Tsukamoto, Takashi

Volltext

δ‑Thiolactones as Prodrugs of Thiol-Based Glutamate Carboxypeptidase II (GCPII) Inhibitors von Ferraris, Dana V, Majer, Pavel, Ni, Chiyou, Slusher, C. Ethan, Rais, Rana, Wu, Ying, Wozniak, Krystyna M, Alt, Jesse, Rojas, Camilo, Slusher, Barbara S, Tsukamoto, Takashi

Volltext

Synthesis of kojic acid derivatives as secondary binding site probes of d-amino acid oxidase von Raje, Mithun, Hin, Niyada, Duvall, Bridget, Ferraris, Dana V., Berry, James F., Thomas, Ajit G., Alt, Jesse, Rojas, Camilo, Slusher, Barbara S., Tsukamoto, Takashi

Volltext

d-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold von Hin, Niyada, Duvall, Bridget, Berry, James F., Ferraris, Dana V., Rais, Rana, Alt, Jesse, Rojas, Camilo, Slusher, Barbara S., Tsukamoto, Takashi

Volltext

Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors von Hin, Niyada, Alt, Jesse, Zimmermann, Sarah C., Delahanty, Greg, Ferraris, Dana V., Rojas, Camilo, Li, Fengxian, Liu, Qin, Dong, Xinzhong, Slusher, Barbara S., Tsukamoto, Takashi

Volltext

Design, Synthesis, and Pharmacological Evaluation of Glutamate Carboxypeptidase II (GCPII) Inhibitors Based on Thioalkylbenzoic Acid Scaffolds von Stoermer, Doris, Vitharana, Dilrukshi, Hin, Niyada, Delahanty, Greg, Duvall, Bridget, Ferraris, Dana V, Grella, Brian S, Hoover, Randall, Rojas, Camilo, Shanholtz, Megan K, Smith, Kyle P, Stathis, Marigo, Wu, Ying, Wozniak, Krystyna M, Slusher, Barbara S, Tsukamoto, Takashi

Volltext