Elucidation of Resistance Mechanisms to Second-Generation ALK Inhibitors Alectinib and Ceritinib in Non–Small Cell Lung Cancer Cells von Dong, Xuyuan, Fernandez-Salas, Ester, Li, Enxiao, Wang, Shaomeng

Volltext

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer von Han, Xin, Wang, Chao, Qin, Chong, Xiang, Weiguo, Fernandez-Salas, Ester, Yang, Chao-Yie, Wang, Mi, Zhao, Lijie, Xu, Tianfeng, Chinnaswamy, Krishnapriya, Delproposto, James, Stuckey, Jeanne, Wang, Shaomeng

Volltext

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Induc... von Qin, Chong, Hu, Yang, Zhou, Bing, Fernandez-Salas, Ester, Yang, Chao-Yie, Liu, Liu, McEachern, Donna, Przybranowski, Sally, Wang, Mi, Stuckey, Jeanne, Meagher, Jennifer, Bai, Longchuan, Chen, Zhuo, Lin, Mei, Yang, Jiuling, Ziazadeh, Danya N, Xu, Fuming, Hu, Jiantao, Xiang, Weiguo, Huang, Liyue, Li, Siwei, Wen, Bo, Sun, Duxin, Wang, Shaomeng

Volltext

Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment von Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.

Volltext

A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation von Zhou, Haibin, Lu, Jianfeng, Liu, Liu, Bernard, Denzil, Yang, Chao-Yie, Fernandez-Salas, Ester, Chinnaswamy, Krishnapriya, Layton, Stephanie, Stuckey, Jeanne, Yu, Qing, Zhou, Weihua, Pan, Zhenqiang, Sun, Yi, Wang, Shaomeng

Volltext

Design of the First‐in‐Class, Highly Potent Irreversible Inhibitor Targeting the Menin‐MLL Protein–Protein Interaction von Xu, Shilin, Aguilar, Angelo, Xu, Tianfeng, Zheng, Ke, Huang, Liyue, Stuckey, Jeanne, Chinnaswamy, Krishnapriya, Bernard, Denzil, Fernández‐Salas, Ester, Liu, Liu, Wang, Mi, McEachern, Donna, Przybranowski, Sally, Foster, Caroline, Wang, Shaomeng

Volltext

Septin Dynamics Are Essential for Exocytosis von Tokhtaeva, Elmira, Capri, Joe, Marcus, Elizabeth A., Whitelegge, Julian P., Khuzakhmetova, Venera, Bukharaeva, Ellya, Deiss-Yehiely, Nimrod, Dada, Laura A., Sachs, George, Fernandez-Salas, Ester, Vagin, Olga

Volltext

Corrigendum to “Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment” [Neoplasia, Volume 22, Issue 2 (2020) 111–119] von Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.

Volltext

EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development von Rej, Rohan Kalyan, Wang, Changwei, Lu, Jianfeng, Wang, Mi, Petrunak, Elyse, Zawacki, Kaitlin P, McEachern, Donna, Fernandez-Salas, Ester, Yang, Chao-Yie, Wang, Lu, Li, Ruiting, Chinnaswamy, Krishnapriya, Wen, Bo, Sun, Duxin, Stuckey, Jeanne, Zhou, Yunlong, Chen, Jianyong, Tang, Guozhi, Wang, Shaomeng

Volltext

Corrigendum to ‘Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment’ Neoplasia, Volume 22, Issue 2 (2020) 111–119 von Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.

Volltext

Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay von Fernández-Salas, Ester, Wang, Joanne, Molina, Yanira, Nelson, Jeremy B, Jacky, Birgitte P S, Aoki, K Roger

Volltext

Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A) von Jacky, Birgitte P S, Garay, Patton E, Dupuy, Jérôme, Nelson, Jeremy B, Cai, Brian, Molina, Yanira, Wang, Joanne, Steward, Lance E, Broide, Ron S, Francis, Joseph, Aoki, K Roger, Stevens, Raymond C, Fernández-Salas, Ester

Volltext

787 AB598, a CD39 inhibitory antibody, promotes immune-mediated tumor control von Clor, Julie, Jin, Ke, Parashar, Kaustubh, Anderson, Amy E, Kates, Lance, Guan, Yihong, Schwager, Sam, Talukdar, Priyanka, Kushwaha, Ritu, Kline, Janine, Fernandez-Salas, Ester, Bowman, Christine

Volltext

880 Inhibition of AXL signaling with AB801 augments anti-tumor immune responses von Leslie, Jhansi, Goshayeshi, Armon, Park, Eugene, Flores, Ruben, Barajas, Gonzalo, Schwager, Samantha C, Stagnaro, Enzo, Kaplan, Angelo, Kline, Janine, Fernandez-Salas, Ester, Paprcka, Susan L

Volltext

A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25 von Rhéaume, Catherine, Cai, Brian B, Wang, Joanne, Fernández-Salas, Ester, Aoki, K Roger, Francis, Joseph, Broide, Ron S

Volltext

The Organellular Chloride Channel Protein CLIC4/mtCLIC Translocates to the Nucleus in Response to Cellular Stress and Accelerates Apoptosis von Suh, Kwang S., Mutoh, Michihiro, Nagashima, Kunio, Fernandez-Salas, Ester, Edwards, Lindsay E., Hayes, Daniel D., Crutchley, John M., Marin, Keith G., Dumont, Rebecca A., Levy, Joshua M., Cheng, Christina, Garfield, Susan, Yuspa, Stuart H.

Volltext

Plasma Membrane Localization Signals in the Light Chain of Botulinum Neurotoxin von Fernández-Salas, Ester, Steward, Lance E., Ho, Helen, Garay, Patton E., Sun, Sarah W., Gilmore, Marcella A., Ordas, Joseph V., Wang, Joanne, Francis, Joseph, Aoki, K. Roger, Boyer, Herbert W.

Volltext

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression von Zhou, Bing, Hu, Jiantao, Xu, Fuming, Chen, Zhuo, Bai, Longchuan, Fernandez-Salas, Ester, Lin, Mei, Liu, Liu, Yang, Chao-Yie, Zhao, Yujun, McEachern, Donna, Przybranowski, Sally, Wen, Bo, Sun, Duxin, Wang, Shaomeng

Volltext

mtCLIC/CLIC4, an Organellular Chloride Channel Protein, Is Increased by DNA Damage and Participates in the Apoptotic Response to p53 von Fernández-Salas, Ester, Suh, Kwang S., Speransky, Vladislav V., Bowers, Wendy L., Levy, Joshua M., Adams, Tracey, Pathak, Kamal R., Edwards, Lindsay E., Hayes, Daniel D., Cheng, Christina, Steven, Alasdair C., Weinberg, Wendy C., Yuspa, Stuart H.

Volltext

CLIC4 is a tumor suppressor for cutaneous squamous cell cancer von SUH, K. Stephen, MALIK, Mariam, SIMPSON, R. Mark, YUSPA, Stuart H, SHUKLA, Anjali, RYSCAVAGE, Andrew, WRIGHT, Lisa, JIVIDEN, Kasey, CRUTCHLEY, John M, DUMONT, Rebecca A, FERNANDEZ-SALAS, Ester, WEBSTER, Joshua D

Volltext