Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes von Scott, Bart L, Pasquini, Marcelo C, Logan, Brent R, Wu, Juan, Devine, Steven M, Porter, David L, Maziarz, Richard T, Warlick, Erica D, Fernandez, Hugo F, Alyea, Edwin P, Hamadani, Mehdi, Bashey, Asad, Giralt, Sergio, Geller, Nancy L, Leifer, Eric, Le-Rademacher, Jennifer, Mendizabal, Adam M, Horowitz, Mary M, Deeg, H Joachim, Horwitz, Mitchell E

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Eprenetapopt Plus Azacitidine After Allogeneic Hematopoietic Stem-Cell Transplantation for TP53 -Mutant Acute Myeloid Leukemia and Myelodysplastic Syndromes von Mishra, Asmita, Tamari, Roni, DeZern, Amy E, Byrne, Michael T, Gooptu, Mahasweta, Chen, Yi-Bin, Deeg, H Joachim, Sallman, David, Gallacher, Phillip, Wennborg, Anders, Hickman, Denice K, Attar, Eyal C, Fernandez, Hugo F

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Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia von Akalin, Altuna, Garrett-Bakelman, Francine E, Kormaksson, Matthias, Busuttil, Jennifer, Zhang, Lu, Khrebtukova, Irina, Milne, Thomas A, Huang, Yongsheng, Biswas, Debabrata, Hess, Jay L, Allis, C David, Roeder, Robert G, Valk, Peter J M, Löwenberg, Bob, Delwel, Ruud, Fernandez, Hugo F, Paietta, Elisabeth, Tallman, Martin S, Schroth, Gary P, Mason, Christopher E, Melnick, Ari, Figueroa, Maria E

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Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation von Figueroa, Maria E., Abdel-Wahab, Omar, Lu, Chao, Ward, Patrick S., Patel, Jay, Shih, Alan, Li, Yushan, Bhagwat, Neha, Vasanthakumar, Aparna, Fernandez, Hugo F., Tallman, Martin S., Sun, Zhuoxin, Wolniak, Kristy, Peeters, Justine K., Liu, Wei, Choe, Sung E., Fantin, Valeria R., Paietta, Elisabeth, Löwenberg, Bob, Licht, Jonathan D., Godley, Lucy A., Delwel, Ruud, Valk, Peter J.M., Thompson, Craig B., Levine, Ross L., Melnick, Ari

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Anthracycline Dose Intensification in Acute Myeloid Leukemia von Fernandez, Hugo F, Sun, Zhuoxin, Yao, Xiaopan, Litzow, Mark R, Luger, Selina M, Paietta, Elisabeth M, Racevskis, Janis, Dewald, Gordon W, Ketterling, Rhett P, Bennett, John M, Rowe, Jacob M, Lazarus, Hillard M, Tallman, Martin S

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Extramedullary Disease in Adult Acute Myeloid Leukemia Is Common but Lacks Independent Significance: Analysis of Patients in ECOG-ACRIN Cancer Research Group Trials, 1980-2008 von Ganzel, Chezi, Manola, Judith, Douer, Dan, Rowe, Jacob M, Fernandez, Hugo F, Paietta, Elisabeth M, Litzow, Mark R, Lee, Ju-Whei, Luger, Selina M, Lazarus, Hillard M, Cripe, Larry D, Wiernik, Peter H, Tallman, Martin S

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Very poor long‐term survival in past and more recent studies for relapsed AML patients: The ECOG‐ACRIN experience von Ganzel, Chezi, Sun, Zhuoxin, Cripe, Larry D., Fernandez, Hugo F., Douer, Dan, Rowe, Jacob M., Paietta, Elisabeth M., Ketterling, Rhett, O'Connell, Michael J., Wiernik, Peter H., Bennett, John M., Litzow, Mark R., Luger, Selina M., Lazarus, Hillard M., Tallman, Martin S.

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Benefit of high-dose daunorubicin in AML induction extends across cytogenetic and molecular groups von Luskin, Marlise R., Lee, Ju-Whei, Fernandez, Hugo F., Abdel-Wahab, Omar, Bennett, John M., Ketterling, Rhett P., Lazarus, Hillard M., Levine, Ross L., Litzow, Mark R., Paietta, Elisabeth M., Patel, Jay P., Racevskis, Janis, Rowe, Jacob M., Tallman, Martin S., Sun, Zhuoxin, Luger, Selina M.

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Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia von DiNardo, Courtney D., Propert, Kathleen J., Loren, Alison W., Paietta, Elisabeth, Sun, Zhuoxin, Levine, Ross L., Straley, Kimberly S., Yen, Katharine, Patel, Jay P., Agresta, Samuel, Abdel-Wahab, Omar, Perl, Alexander E., Litzow, Mark R., Rowe, Jacob M., Lazarus, Hillard M., Fernandez, Hugo F., Margolis, David J., Tallman, Martin S., Luger, Selina M., Carroll, Martin

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Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS von Barreyro, Laura, Will, Britta, Bartholdy, Boris, Zhou, Li, Todorova, Tihomira I., Stanley, Robert F., Ben-Neriah, Susana, Montagna, Cristina, Parekh, Samir, Pellagatti, Andrea, Boultwood, Jacqueline, Paietta, Elisabeth, Ketterling, Rhett P., Cripe, Larry, Fernandez, Hugo F., Greenberg, Peter L., Tallman, Martin S., Steidl, Christian, Mitsiades, Constantine S., Verma, Amit, Steidl, Ulrich

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Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program von Park, Sun-Mi, Gönen, Mithat, Vu, Ly, Minuesa, Gerard, Tivnan, Patrick, Barlowe, Trevor S, Taggart, James, Lu, Yuheng, Deering, Raquel P, Hacohen, Nir, Figueroa, Maria E, Paietta, Elisabeth, Fernandez, Hugo F, Tallman, Martin S, Melnick, Ari, Levine, Ross, Leslie, Christina, Lengner, Christopher J, Kharas, Michael G

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Myeloablative versus Reduced-Intensity Conditioning for Hematopoietic Cell Transplantation in Acute Myelogenous Leukemia and Myelodysplastic Syndromes—Long-Term Follow-Up of the BM... von Scott, Bart L., Pasquini, Marcelo C., Fei, Mingwei, Fraser, Raphael, Wu, Juan, Devine, Steve M., Porter, David L., Maziarz, Richard T., Warlick, Erica, Fernandez, Hugo F., Soiffer, Robert J., Alyea, Edwin, Hamadani, Mehdi, Bashey, Asad, Giralt, Sergio, Geller, Nancy L., Leifer, Eric, Hourigan, Christopher S., Gui, Gege, Mendizabal, Adam, Horowitz, Mary M., Deeg, H. Joachim, Horwitz, Mitchell E.

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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment von Le, Bac Viet, Podszywalow-Bartnicka, Paulina, Maifrede, Silvia, Sullivan-Reed, Katherine, Nieborowska-Skorska, Margaret, Golovine, Konstantin, Yao, Juo-Chin, Nejati, Reza, Cai, Kathy Q., Caruso, Lisa Beatrice, Swatler, Julian, Dabrowski, Michal, Lian, Zhaorui, Valent, Peter, Paietta, Elisabeth M., Levine, Ross L., Fernandez, Hugo F., Tallman, Martin S., Litzow, Mark R., Huang, Jian, Challen, Grant A., Link, Daniel, Tempera, Italo, Wasik, Mariusz A., Piwocka, Katarzyna, Skorski, Tomasz

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A randomized phase II study to evaluate tacrolimus in combination with sirolimus or methotrexate after allogeneic hematopoietic cell transplantation von PIDALA, Joseph, KIM, Jongphil, JANSSEN, William E, VEERAPATHRAN, Anandaraman, BETTS, Brian C, LOCKE, Frederick L, AYALA, Ernesto, FIELD, Teresa, OCHOA, Leonel, ALSINA, Melissa, ANASETTI, Claudio, JIM, Heather, KHARFAN-DABAJA, Mohamed A, NISHIHORI, Taiga, FERNANDEZ, Hugo F, TOMBLYN, Marcie, PEREZ, Lia, PERKINS, Janelle, MIAN XU

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In vivo IL-12/IL-23p40 neutralization blocks Th1/Th17 response after allogeneic hematopoietic cell transplantation von Pidala, Joseph, Beato, Francisca, Kim, Jongphil, Betts, Brian, Jim, Heather, Sagatys, Elizabeth, Levine, John E, Ferrara, James L M, Ozbek, Umut, Ayala, Ernesto, Davila, Marco, Fernandez, Hugo F, Field, Teresa, Kharfan-Dabaja, Mohamed A, Khaira, Divis, Khimani, Farhad, Locke, Frederick L, Mishra, Asmita, Nieder, Michael, Nishihori, Taiga, Perez, Lia, Riches, Marcie, Anasetti, Claudio

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New trends in the standard of care for initial therapy of acute myeloid leukemia von Fernandez, Hugo F

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Extramedullary acute myeloid leukemia presenting in young adults demonstrates sensitivity to high-dose anthracycline: a subset analysis from ECOG-ACRIN 1900 von Fernandez, Hugo F, Sun, Zhuoxin, Litzow, Mark R, Luger, Selina M, Paietta, Elisabeth, Racevskis, Janis, Levine, Ross L, Patel, Jay P, Abdel-Wahab, Omar, Ketterling, Rhett P, Dewald, Gordon W, Bennett, John M, Rowe, Jacob M, Lazarus, Hillard M, Tallman, Martin S

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Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease von Hourigan, Christopher S., Dillon, Laura W., Gui, Gege, Logan, Brent R., Fei, Mingwei, Ghannam, Jack, Li, Yuesheng, Licon, Abel, Alyea, Edwin P., Bashey, Asad, Deeg, H. Joachim, Devine, Steven M., Fernandez, Hugo F., Giralt, Sergio, Hamadani, Mehdi, Howard, Alan, Maziarz, Richard T., Porter, David L., Scott, Bart L., Warlick, Erica D., Pasquini, Marcelo C., Horwitz, Mitchell E.

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Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN... von Strickland, Stephen A, Sun, Zhuoxin, Ketterling, Rhett P, Cherry, Athena M, Cripe, Larry D, Dewald, Gordon, Fernandez, Hugo, Hicks, Gary A, Higgins, Rodney R, Lazarus, Hillard M, Litzow, Mark R, Luger, Selina M, Paietta, Elisabeth M, Rowe, Jacob M, Vance, Gail H, Wiernik, Peter, Wiktor, Anne E, Zhang, Yanming, Tallman, Martin S

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Prolonged sirolimus administration after allogeneic hematopoietic cell transplantation is associated with decreased risk for moderate-severe chronic graft-versus-host disease von Pidala, Joseph, Kim, Jongphil, Alsina, Melissa, Ayala, Ernesto, Betts, Brian C, Fernandez, Hugo F, Field, Teresa, Jim, Heather, Kharfan-Dabaja, Mohamed A, Locke, Frederick L, Mishra, Asmita, Nishihori, Taiga, Ochoa-Bayona, Leonel, Perez, Lia, Riches, Marcie, Anasetti, Claudio

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