Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma von Tsang, Tiffany, Posimo, Jessica M., Gudiel, Andrea A., Cicchini, Michelle, Feldser, David M., Brady, Donita C.

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Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis von Lin, Jeffrey H., Huffman, Austin P., Wattenberg, Max M., Walter, David M., Carpenter, Erica L., Feldser, David M., Beatty, Gregory L., Furth, Emma E., Vonderheide, Robert H.

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Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis von Kharbanda, Akriti, Walter, David M., Gudiel, Andrea A., Schek, Nancy, Feldser, David M., Witze, Eric S.

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Requirement for NF-[kappa]B signalling in a mouse model of lung adenocarcinoma von Meylan, Etienne, Dooley, Alison L, Feldser, David M, Shen, Lynn, Turk, Erin, Ouyang, Chensi, Jacks, Tyler

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Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma von Walter, David M, Venancio, Olivia S, Buza, Elizabeth L, Tobias, John W, Deshpande, Charuhas, Gudiel, A Andrea, Kim-Kiselak, Caroline, Cicchini, Michelle, Yates, Travis J, Feldser, David M

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Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma von Meylan, Etienne, Dooley, Alison L., Feldser, David M., Shen, Lynn, Turk, Erin, Ouyang, Chensi, Jacks, Tyler

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Off and back-on again: a tumor suppressor’s tale von Acosta, Jonuelle, Wang, Walter, Feldser, David M.

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Short Telomeres Limit Tumor Progression In Vivo by Inducing Senescence von Feldser, David M., Greider, Carol W.

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Stage-specific sensitivity to p53 restoration during lung cancer progression von Jacks, Tyler, Feldser, David M, Kostova, Kamena K, Winslow, Monte M, Taylor, Sarah E, Cashman, Chris, Whittaker, Charles A, Sanchez-Rivera, Francisco J, Resnick, Rebecca, Bronson, Roderick, Hemann, Michael T

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The p53 transcriptional response across tumor types reveals core and senescence-specific signatures modulated by long noncoding RNAs von Tesfaye, Ephrath, Martinez-Terroba, Elena, Bendor, Jordan, Winkler, Lauren, Olivero, Christiane, Chen, Kevin, Feldser, David M., Zamudio, Jesse R., Dimitrova, Nadya

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A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response von Huarte, Maite, Guttman, Mitchell, Feldser, David, Garber, Manuel, Koziol, Magdalena J., Kenzelmann-Broz, Daniela, Khalil, Ahmad M., Zuk, Or, Amit, Ido, Rabani, Michal, Attardi, Laura D., Regev, Aviv, Lander, Eric S., Jacks, Tyler, Rinn, John L.

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RB constrains lineage fidelity and multiple stages of tumour progression and metastasis von Walter, David M., Yates, Travis J., Ruiz-Torres, Miguel, Kim-Kiselak, Caroline, Gudiel, A. Andrea, Deshpande, Charuhas, Wang, Walter Z., Cicchini, Michelle, Stokes, Kate L., Tobias, John W., Buza, Elizabeth, Feldser, David M.

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals von Kellis, Manolis, Feldser, David, Cassady, John P, Amit, Ido, Lander, Eric S, Zuk, Or, Lin, Michael F, Carey, Bryce W, Garber, Manuel, Mikkelsen, Tarjei S, Jacks, Tyler, Hacohen, Nir, Guttman, Mitchell, French, Courtney, Cabili, Moran N, Huarte, Maite, Regev, Aviv, Rinn, John L, Jaenisch, Rudolf, Bernstein, Bradley E

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p53 restoration in small cell lung cancer identifies a latent cyclophilin-dependent necrosis mechanism von Acosta, Jonuelle, Li, Qinglan, Freeburg, Nelson F., Murali, Nivitha, Indeglia, Alexandra, Grothusen, Grant P., Cicchini, Michelle, Mai, Hung, Gladstein, Amy C., Adler, Keren M., Doerig, Katherine R., Li, Jinyang, Ruiz-Torres, Miguel, Manning, Kimberly L., Stanger, Ben Z., Busino, Luca, Murphy, Maureen, Wan, Liling, Feldser, David M.

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LKB1 inactivation modulates chromatin accessibility to drive metastatic progression von Pierce, Sarah E., Granja, Jeffrey M., Corces, M. Ryan, Brady, Jennifer J., Tsai, Min K., Pierce, Aubrey B., Tang, Rui, Chu, Pauline, Feldser, David M., Chang, Howard Y., Bassik, Michael C., Greenleaf, William J., Winslow, Monte M.

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LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer von Murray, Christopher W., Brady, Jennifer J., Han, Mingqi, Cai, Hongchen, Tsai, Min K., Pierce, Sarah E., Cheng, Ran, Demeter, Janos, Feldser, David M., Jackson, Peter K., Shackelford, David B., Winslow, Monte M.

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PKC epsilon Is Required for KRAS-Driven Lung Tumorigenesis von Garg, Rachana, Cooke, Mariana, Benavides, Fernando, Abba, Martin C., Cicchini, Michelle, Feldser, David M., Kazanietz, Marcelo G.

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Suppression of lung adenocarcinoma progression by Nkx2-1 von Winslow, Monte M., Dayton, Talya L., Verhaak, Roel G. W., Kim-Kiselak, Caroline, Snyder, Eric L., Feldser, David M., Hubbard, Diana D., DuPage, Michel J., Whittaker, Charles A., Hoersch, Sebastian, Yoon, Stephanie, Crowley, Denise, Bronson, Roderick T., Chiang, Derek Y., Meyerson, Matthew, Jacks, Tyler

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RB depletion is required for the continuous growth of tumors initiated by loss of RB von Doan, Alex, Arand, Julia, Gong, Diana, Drainas, Alexandros P., Shue, Yan Ting, Lee, Myung Chang, Zhang, Shuyuan, Walter, David M., Chaikovsky, Andrea C., Feldser, David M., Vogel, Hannes, Dow, Lukas E., Skotheim, Jan M., Sage, Julien

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Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration von Sánchez-Rivera, Francisco J., Ryan, Jeremy, Soto-Feliciano, Yadira M., Beytagh, Mary Clare, Xuan, Lucius, Feldser, David M., Hemann, Michael T., Zamudio, Jesse, Dimitrova, Nadya, Letai, Anthony, Jacks, Tyler

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