Gut hormone pharmacology of a novel GPR119 agonist (GSK1292263), metformin, and sitagliptin in type 2 diabetes mellitus: results from two randomized studies von Nunez, Derek J, Bush, Mark A, Collins, David A, McMullen, Susan L, Gillmor, Dawn, Apseloff, Glen, Atiee, George, Corsino, Leonor, Morrow, Linda, Feldman, Paul L

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Insights into the Chemical Discovery of Remifentanil von Feldman, Paul L.

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Discovery of a Highly Potent, Nonabsorbable Apical Sodium-Dependent Bile Acid Transporter Inhibitor (GSK2330672) for Treatment of Type 2 Diabetes von Wu, Yulin, Aquino, Christopher J, Cowan, David J, Anderson, Don L, Ambroso, Jeff L, Bishop, Michael J, Boros, Eric E, Chen, Lihong, Cunningham, Alan, Dobbins, Robert L, Feldman, Paul L, Harston, Lindsey T, Kaldor, Istvan W, Klein, Ryan, Liang, Xi, McIntyre, Maggie S, Merrill, Christine L, Patterson, Kristin M, Prescott, Judith S, Ray, John S, Roller, Shane G, Yao, Xiaozhou, Young, Andrew, Yuen, Josephine, Collins, Jon L

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A 28-Day Toxicity Study of Tenofovir Alafenamide Hemifumarate by Subcutaneous Infusion in Rats and Dogs von Zane, Doris, Roller, Shane, Shelton, Josephine, Singh, Roshni, Jain, Rachna, Wang, Yan, Yang, Bing, Felx, Melanie, Alessi, Thomas, Feldman, Paul L

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Development and Regulatory Challenges for Peptide Therapeutics von Zane, Doris, Feldman, Paul L., Sawyer, Tomi, Sobol, Zhanna, Hawes, Jessica

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Quality guidelines for oral drug candidates: dose, solubility and lipophilicity von Bayliss, Martin K., Butler, James, Feldman, Paul L., Green, Darren V.S., Leeson, Paul D., Palovich, Michael R., Taylor, Anthony J.

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Nitric Oxide: A New Paradigm for Second Messengers von Kerwin, James F, Lancaster, Jack R, Feldman, Paul L

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CNS 7056: a novel ultra-short-acting Benzodiazepine von Kilpatrick, Gavin J, McIntyre, Margaret S, Cox, Richard F, Stafford, Jeffrey A, Pacofsky, Gregory J, Lovell, Gwyer G, Wiard, Robert P, Feldman, Paul L, Collins, Holly, Waszczak, Barbara L, Tilbrook, Gary S

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Tenofovir Alafenamide for HIV Prevention: Review of the Proceedings from the Gates Foundation Long-Acting TAF Product Development Meeting von Romano, Joseph W, Baum, Marc M, Demkovich, Zach R, Diana, Frank, Dobard, Charles, Feldman, Paul L, Garcia-Lerma, J Gerardo, Grattoni, Alessandro, Gunawardana, Manjula, Ho, Duy-Khiet, Hope, Thomas J, Massud, Ivana, Milad, Mark, Moss, John A, Pons-Faudoa, Fernanda P, Roller, Shane, van der Straten, Ariane, Srinivasan, Selvi, Veazey, Ronald S, Zane, Doris

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Potent, Selective, and Orally Efficacious Antagonists of Melanin-Concentrating Hormone Receptor 1 von Tavares, Francis X, Al-Barazanji, Kamal A, Bigham, Eric C, Bishop, Michael J, Britt, Christy S, Carlton, David L, Feldman, Paul L, Goetz, Aaron S, Grizzle, Mary K, Guo, Yu C, Handlon, Anthony L, Hertzog, Donald L, Ignar, Diane M, Lang, Daniel G, Ott, Ronda J, Peat, Andrew J, Zhou, Hui-Qiang

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Synthesis of Ultra-Short-Acting Neuromuscular Blocker GW 0430:  A Remarkably Stereo- and Regioselective Synthesis of Mixed Tetrahydroisoquinolinium Chlorofumarates von Samano, Vicente, Ray, John A, Thompson, James B, Mook, Robert A, Jung, David K, Koble, Cecilia S, Martin, Michael T, Bigham, Eric C, Regitz, Craig S, Feldman, Paul L, Boros, Eric E

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Bis- and Mixed-Tetrahydroisoquinolinium Chlorofumarates:  New Ultra-Short-Acting Nondepolarizing Neuromuscular Blockers von Boros, Eric E, Bigham, Eric C, Boswell, G. Evan, Mook, Robert A, Patel, Sanjay S, Savarese, John J, Ray, John A, Thompson, James B, Hashim, Mir A, Wisowaty, James C, Feldman, Paul L, Samano, Vicente

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An efficient and practical total synthesis of (+)-vincamine from L-aspartic acid von Gmeiner, Peter, Feldman, Paul L, Chu-Moyer, Margaret Y, Rapoport, Henry

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Design and Synthesis of Conformationally Constrained Analogs of 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one (Ro 20-1724) as Potent Inhibitors of cAMP-Specific Phosphodiesterase von Brackeen, Marcus F, Stafford, Jeffrey A, Cowan, David J, Brown, Peter J, Domanico, Paul L, Feldman, Paul L, Rose, Dudley, Strickland, Alan B, Veal, James M, Verghese, Margrith

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6-(4-Chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-Based Melanin-Concentrating Hormone Receptor 1 Antagonist von Tavares, Francis X, Al-Barazanji, Kamal A, Bishop, Michael J, Britt, Christy S, Carlton, David L, Cooper, Joel P, Feldman, Paul L, Garrido, Dulce M, Goetz, Aaron S, Grizzle, Mary K, Hertzog, Donald L, Ignar, Diane M, Lang, Daniel G, McIntyre, Maggie S, Ott, Ronda J, Peat, Andrew J, Zhou, Hui-Qiang

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Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat: A comparison with mivacurium von SAVARESE, John J, BELMONT, Matthew R, SPITZER, Timothy, COHN, Douglas L, MORGAN, Philip, WASTILA, William B, HASHIM, Mir A, MOOK, Robert A, BOROS, Eric E, SAMANO, Vicente, PATEL, Sanjay S, FELDMAN, Paul L, SCHULTZ, Jan-Ake I, MCNULTY, Michael

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Degradative Rearrangements of N-(t-Butyloxycarbonyl)-O-methanesulfonyl-hydroxamic Acids:  A Novel, Reagent-Based Alternative to the Lossen Rearrangement1 von Stafford, Jeffrey A, Gonzales, Stephen S, Barrett, David G, Suh, Edward M, Feldman, Paul L

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Continuous Subcutaneous Delivery of a Glucagon Analog, ICA6150349, to Rats and Nonhuman Primates Demonstrates Safety and Tolerability in a 14-Day Toxicity Study von ZANE, DORIS, SINGH, ROSHNI, SHELTON, JOSEPHINE, ROLLER, SHANE, PAULIK, MARK, WAY, JAMES, BLACKWELL, WILLIAM C., SRIVASTAVA, VED, HODGE, REBECCA, FELDMAN, PAUL L., ALESSI, THOMAS R.

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Neuromuscular Blocking Activity and Therapeutic Potential of Mixed-Tetrahydroisoquinolinium Halofumarates and Halosuccinates in Rhesus Monkeys von Boros, Eric E, Samano, Vicente, Ray, John A, Thompson, James B, Jung, David K, Kaldor, Istvan, Koble, Cecilia S, Martin, Michael T, Styles, Virgil L, Mook, Robert A, Feldman, Paul L, Savarese, John J, Belmont, Matthew R, Bigham, Eric C, Boswell, G. Evan, Hashim, Mir A, Patel, Sanjay S, Wisowaty, James C, Bowers, Gary D, Moseley, Caroline L, Walsh, John S, Reese, Mindy J, Rutkowske, Randy D, Sefler, Andrea M, Spitzer, Timothy D

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ICA6150349, a Highly Selective Glucagon Agonist, in Combination with Exenatide Significantly Reduces Weight and Glucose in Obese and Diabetic Rats von PAULIK, MARK, TLUSTY, TOM, GRIZZLE, MARY K., COPELAND, MARCI, WENG, SHARON, BLACKWELL, WILLIAM C., SRIVASTAVA, VED, WAY, JAMES, ROLLER, SHANE, ZANE, DORIS, HODGE, REBECCA, YOUNG, ANDREW A., FELDMAN, PAUL L.

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