Screening for Antiviral Inhibitors of the HIV Integrase–LEDGF/p75 Interaction Using the AlphaScreen™ Luminescent Proximity Assay von Hou, Yan, McGuinness, Debra E., Prongay, Andrew J., Feld, Boris, Ingravallo, Paul, Ogert, Robert A., Lunn, Charles A., Howe, John A.

Volltext

A high-throughput assay for the adenylation reaction of bacterial DNA ligase von Miesel, Lynn, Kravec, Cynthia, Xin, Alan-Tianpei, McMonagle, Patricia, Ma, Sarah, Pichardo, John, Feld, Boris, Barrabee, Ellen, Palermo, Robert

Volltext

Thiourea inhibitors of herpes viruses. Part 2: N-Benzyl- N′-arylthiourea inhibitors of CMV von Bloom, Jonathan D., Dushin, Russell G., Curran, Kevin J., Donahue, Fran, Norton, Emily B., Terefenko, Eugene, Jones, Thomas R., Ross, Adma A., Feld, Boris, Lang, Stanley A., DiGrandi, Martin J.

Volltext

RFI-641, a Potent Respiratory Syncytial Virus Inhibitor von Huntley, Clayton C, Weiss, William J, Gazumyan, Anna, Buklan, Aron, Feld, Boris, Hu, William, Jones, Thomas R, Murphy, Timothy, Nikitenko, Antonia A, O'Hara, Bryan, Prince, Gregory, Quartuccio, Susan, Raifeld, Yuri E, Wyde, Philip, O'Connell, John F

Volltext

Thiourea inhibitors of herpes viruses. part 1: bis-(aryl)thiourea inhibitors of CMV von Bloom, Jonathan D., DiGrandi, Martin J., Dushin, Russell G., Curran, Kevin J., Ross, Adma A., Norton, Emily B., Terefenko, Eugene, Jones, Thomas R., Feld, Boris, Lang, Stanley A.

Volltext

Specific Inhibition of Human Cytomegalovirus Glycoprotein B-Mediated Fusion by a Novel Thiourea Small Molecule von JONES, Thomas R, LEE, Shi-Wu, JOHANN, Stephen V, RAZINKOV, Vladimir, VISALLI, Robert J, FELD, Boris, BLOOM, Jonathan D, O'CONNELL, John

Volltext

Novel Class of Thiourea Compounds That Inhibit Herpes Simplex Virus Type 1 DNA Cleavage and Encapsidation: Resistance Maps to the UL6 Gene von van Zeijl, M, Fairhurst, J, Jones, T R, Vernon, S K, Morin, J, LaRocque, J, Feld, B, O'Hara, B, Bloom, J D, Johann, S V

Volltext

Identification of Small Molecule Compounds That Selectively Inhibit Varicella-Zoster Virus Replication von Visalli, Robert J., Fairhurst, Jeanette, Srinivas, Shamala, Hu, William, Feld, Boris, DiGrandi, Martin, Curran, Kevin, Ross, Adma, Bloom, Jonathan D., van Zeijl, Marja, Jones, Thomas R., O'Connell, John, Cohen, Jeffrey I.

Volltext

Structure–Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase von Chen, Kevin X, Vibulbhan, Bancha, Yang, Weiying, Sannigrahi, Mousumi, Velazquez, Francisco, Chan, Tin-Yau, Venkatraman, Srikanth, Anilkumar, Gopinadhan N, Zeng, Qingbei, Bennet, Frank, Jiang, Yueheng, Lesburg, Charles A, Duca, Jose, Pinto, Patrick, Gavalas, Stephen, Huang, Yuhua, Wu, Wanli, Selyutin, Oleg, Agrawal, Sony, Feld, Boris, Huang, Hsueh-Cheng, Li, Cheng, Cheng, Kuo-Chi, Shih, Neng-Yang, Kozlowski, Joseph A, Rosenblum, Stuart B, Njoroge, F. George

Volltext

I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles von Anilkumar, Gopinadhan N., Lesburg, Charles A., Selyutin, Oleg, Rosenblum, Stuart B., Zeng, Qingbei, Jiang, Yueheng, Chan, Tin-Yau, Pu, Haiyan, Vaccaro, Henry, Wang, Li, Bennett, Frank, Chen, Kevin X., Duca, Jose, Gavalas, Stephen, Huang, Yuhua, Pinto, Patrick, Sannigrahi, Mousumi, Velazquez, Francisco, Venkatraman, Srikanth, Vibulbhan, Bancha, Agrawal, Sony, Butkiewicz, Nancy, Feld, Boris, Ferrari, Eric, He, Zhiqing, Jiang, Chuan-kui, Palermo, Robert E., Mcmonagle, Patricia, Huang, H.-C., Shih, Neng-Yang, Njoroge, George, Kozlowski, Joseph A.

Volltext

A Novel Class of Highly Potent Irreversible Hepatitis C Virus NS5B Polymerase Inhibitors von Chen, Kevin X, Lesburg, Charles A, Vibulbhan, Bancha, Yang, Weiying, Chan, Tin-Yau, Venkatraman, Srikanth, Velazquez, Francisco, Zeng, Qingbei, Bennett, Frank, Anilkumar, Gopinadhan N, Duca, Jose, Jiang, Yueheng, Pinto, Patrick, Wang, Li, Huang, Yuhua, Selyutin, Oleg, Gavalas, Stephen, Pu, Haiyan, Agrawal, Sony, Feld, Boris, Huang, Hsueh-Cheng, Li, Cheng, Cheng, Kuo-Chi, Shih, Neng-Yang, Kozlowski, Joseph A, Rosenblum, Stuart B, Njoroge, F. George

Volltext

Identification of Anthranilic Acid Derivatives as a Novel Class of Allosteric Inhibitors of Hepatitis C NS5B Polymerase von Nittoli, Thomas, Curran, Kevin, Insaf, Shabana, DiGrandi, Martin, Orlowski, Mark, Chopra, Rajiv, Agarwal, Atul, Howe, Anita Y. M, Prashad, Amar, Floyd, M. Brawner, Johnson, Bernard, Sutherland, Alan, Wheless, Karen, Feld, Boris, O'Connell, John, Mansour, Tarek S, Bloom, Jonathan

Volltext

Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site von Gopalsamy, Ariamala, Chopra, Rajiv, Lim, Kitae, Ciszewski, Gregory, Shi, Mengxiao, Curran, Kevin J, Sukits, Steven F, Svenson, Kristine, Bard, Joel, Ellingboe, John W, Agarwal, Atul, Krishnamurthy, Girija, Howe, Anita Y. M, Orlowski, Mark, Feld, Boris, O'Connell, John, Mansour, Tarek S

Volltext

Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA... von Gopalsamy, Ariamala, Aplasca, Alexis, Ciszewski, Gregory, Park, Kaapjoo, Ellingboe, John W, Orlowski, Mark, Feld, Boris, Howe, Anita Y M

Volltext

Discovery of Pyrano[3,4-b]indoles as Potent and Selective HCV NS5B Polymerase Inhibitors von Gopalsamy, Ariamala, Lim, Kitae, Ciszewski, Gregory, Park, Kaapjoo, Ellingboe, John W, Bloom, Jonathan, Insaf, Shabana, Upeslacis, Janis, Mansour, Tarek S, Krishnamurthy, Girija, Damarla, Murthy, Pyatski, Yelena, Ho, Douglas, Howe, Anita Y. M, Orlowski, Mark, Feld, Boris, O'Connell, John

Volltext

Novel substituted pyrimidines as HCV replication (replicase) inhibitors von Kwong, Cecil D., Clark, Jeremy L., Fowler, Anita T., Geng, Feng, Kezar, Hollis S., Roychowdhury, Abhijit, Reynolds, Robert C., Maddry, Joseph A., Ananthan, Subramaniam, Secrist, John A., Shih, Neng-Yang, Piwinski, John J., Li, Cheng, Feld, Boris, Huang, Hsueh-Cheng, Tong, Xiao, George Njoroge, F., Arasappan, Ashok

Volltext

Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent... von GOPALSAMY, Ariamala, MENGXIAO SHI, CISZEWSKI, Gregory, PARK, Kaapjoo, ELLINGBOE, John W, ORLOWSKI, Mark, FELD, Boris, HOWE, Anita Y. M

Volltext

Novel Nonnucleoside Inhibitor of Hepatitis C Virus RNA-Dependent RNA Polymerase von HOWE, Anita Y. M, BLOOM, Johnathan, GORCZYCA, William P, HERRRNANN, Steve, JOHANN, Stephen, XIAOQUN JIANG, KIMBERLAND, Michelle L, KRISNAMURTHY, Girija, OLSON, Matthew, ORLOWSKI, Mark, SWANBERG, Steve, THOMPSON, Ian, BALDICK, Carl J, THORN, Megan, DEL VECCHIO, Alfred, YOUNG, Dorothy C, VAN ZEIJL, Marja, ELLINGBOE, John W, UPESLACIS, Janis, COLLETT, Marc, MANSOUR, Tarek S, O'CONNELL, John F, BENETATOS, Christopher A, HUIMING CHENG, CHRISTENSEN, Joel S, CHUNDURU, Srinivas K, COBURN, Glen A, FELD, Boris, GOPALSAMY, Ariamala

Volltext

Thiourea inhibitors of herpesviruses. Part 3: Inhibitors of varicella zoster virus von Di Grandi, Martin J, Curran, Kevin J, Feigelson, Gregg, Prashad, Amar, Ross, Adma A, Visalli, Robert, Fairhurst, Jeanette, Feld, Boris, Bloom, Jonathan D

Volltext

Design and Syntheses of 1,6-Naphthalene Derivatives as Selective HCMV Protease Inhibitors von Gopalsamy, Ariamala, Lim, Kitae, Ellingboe, John W., Mitsner, Boris, Nikitenko, Antonia, Upeslacis, Janis, Mansour, Tarek S., Olson, Matthew W., Bebernitz, Geraldine A., Grinberg, Diane, Feld, Boris, Moy, Franklin J., O'Connell, John

Volltext