Lysosomes as targets for cancer therapy von FEHRENBACHER, Nicole, JÄÄTTELÄ, Marja

Volltext

Ras/MAPK signaling from endomembranes von Fehrenbacher, Nicole, Bar-Sagi, Dafna, Philips, Mark

Volltext

Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors von Sung, Pamela J., Tsai, Frederick D., Vais, Horia, Court, Helen, Yang, Jun, Fehrenbacher, Nicole, Foskett, J. Kevin, Philips, Mark R.

Volltext

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization von Nylandsted, Jesper, Gyrd-Hansen, Mads, Danielewicz, Agnieszka, Fehrenbacher, Nicole, Lademann, Ulrik, Høyer-Hansen, Maria, Weber, Ekkehard, Multhoff, Gabriele, Rohde, Mikkel, Jäättelä, Marja

Volltext

Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2 von Fehrenbacher, Nicole, Bastholm, Lone, Kirkegaard-Sørensen, Thomas, Rafn, Bo, Bøttzauw, Trine, Nielsen, Christina, Weber, Ekkehard, Shirasawa, Senji, Kallunki, Tuula, Jäättelä, Marja

Volltext

FKBP12 Binds to Acylated H-Ras and Promotes Depalmitoylation von Ahearn, Ian M., Tsai, Frederick D., Court, Helen, Zhou, Mo, Jennings, Benjamin C., Ahmed, Mahiuddin, Fehrenbacher, Nicole, Linder, Maurine E., Philips, Mark R.

Volltext

ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signaling Network Activating Myeloid Zinc Finger-1-Dependent Cathepsin B Expression von Rafn, Bo, Nielsen, Christian Friberg, Andersen, Sofie Hagel, Szyniarowski, Piotr, Corcelle-Termeau, Elisabeth, Valo, Erkka, Fehrenbacher, Nicole, Olsen, Charlotta Johanne, Daugaard, Mads, Egebjerg, Christina, Bøttzauw, Trine, Kohonen, Pekka, Nylandsted, Jesper, Hautaniemi, Sampsa, Moreira, José, Jäättelä, Marja, Kallunki, Tuula

Volltext

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation von Ostenfeld, Marie Stampe, Høyer-Hansen, Maria, Bastholm, Lone, Fehrenbacher, Nicole, Olsen, Ole Dines, Groth-Pedersen, Line, Puustinen, Pietri, Kirkegaard-Sørensen, Thomas, Nylandsted, Jesper, Farkas, Thomas, Jäättelä, Marja

Volltext

Targeting RAS - will GPR31 deliver us a new path forward? von Fehrenbacher, Nicole, Philips, Mark R.

Volltext

Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9 von Gyrd-Hansen, Mads, Farkas, Thomas, Fehrenbacher, Nicole, Bastholm, Lone, Høyer-Hansen, Maria, Elling, Folmer, Wallach, David, Flavell, Richard, Kroemer, Guido, Nylandsted, Jesper, Jäättelä, Marja

Volltext

GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase von Kuchay, Shafi, Wang, Hui, Marzio, Antonio, Jain, Kunj, Homer, Harrison, Fehrenbacher, Nicole, Philips, Mark R., Zheng, Ning, Pagano, Michele

Volltext

Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-β, and Bcl-2 von Høyer-Hansen, Maria, Bastholm, Lone, Szyniarowski, Piotr, Campanella, Michelangelo, Szabadkai, György, Farkas, Thomas, Bianchi, Katiuscia, Fehrenbacher, Nicole, Elling, Folmer, Rizzuto, Rosario, Mathiasen, Ida Stenfeldt, Jäättelä, Marja

Volltext

Single-Walled Carbon Nanotubes Deliver Peptide Antigen into Dendritic Cells and Enhance IgG Responses to Tumor-Associated Antigens von Villa, Carlos H, Dao, Tao, Ahearn, Ian, Fehrenbacher, Nicole, Casey, Emily, Rey, Diego A, Korontsvit, Tatyana, Zakhaleva, Victoriya, Batt, Carl A, Philips, Mark R, Scheinberg, David A

Volltext

Intracellular Signaling: Peripatetic Ras von Fehrenbacher, Nicole, Philips, Mark

Volltext

Effective tumor cell death by σ-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress von OSTENFELD, Marie Stampe, FEHRENBACHER, Nicole, HØYER-HANSEN, Maria, THOMSEN, Christian, FARKAS, Thomas, JÄÄTTELÄ, Marja

Volltext

Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association von Zhou, Mo, Kuruvilla, Leena, Shi, Xiarong, Viviano, Stephen, Ahearn, Ian M., Amendola, Caroline R., Su, Wenjuan, Badri, Sana, Mahaffey, James, Fehrenbacher, Nicole, Skok, Jane, Schlessinger, Joseph, Turk, Benjamin E., Calderwood, David A., Philips, Mark R.

Volltext

The G protein-coupled receptor GPR31 promotes membrane association of KRAS von Fehrenbacher, Nicole, Tojal da Silva, Israel, Ramirez, Craig, Zhou, Yong, Cho, Kwang-Jin, Kuchay, Shafi, Shi, Jie, Thomas, Susan, Pagano, Michele, Hancock, John F, Bar-Sagi, Dafna, Philips, Mark R

Volltext

Correction for Gyrd-Hansen et al., "Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9" von Gyrd-Hansen, Mads, Farkas, Thomas, Fehrenbacher, Nicole, Bastholm, Lone, Høyer-Hansen, Maria, Elling, Folmer, Wallach, David, Flavell, Richard, Kroemer, Guido, Nylandsted, Jesper, Jäättelä, Marja

Volltext

Sensitization to the lysosomal cell death pathway upon immortalization and transformation von FEHRENBACHER, Nicole, GYRD-HANSEN, Mads, POULSEN, Birgit, FELBOR, Ute, KALLUNKI, Tuula, BOES, Marianne, WEBER, Ekkehard, LEIST, Marcel, JÄÄTTELÄ, Marja

Volltext

ErbB2 signaling pathways in the regulation of cathepsin activity von Kallunki, Tuula, Rafn, Bo, Szyniatowski, Piotr, Fehrenbacher, Nicole, Boettzauw, Trine, Nielsen, Christina, Nylandsted, Jesper, Jaeaettelae, Marja

Volltext