Larotrectinib efficacy and safety in TRK fusion cancer: An expanded clinical dataset showing consistency in an age and tumor agnostic approach von Tan, D.S.W., Lassen, U.N., Albert, C.M., Kummar, S., van Tilburg, C., Dubois, S.G., Geoerger, B., Mascarenhas, L., Federman, N., Basu-Mallick, A., Doz, F., Berlin, J.D., Oh, D.-Y., Bielack, S., McDermott, R., Cruickshank, S., Ku, N.C., Cox, M.C., Drilon, A., Hong, D.S.

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Larotrectinib efficacy and safety in TRK fusion cancer: An expanded clinical dataset showing consistency in an age and tumor agnostic approach von Lassen, U N, Albert, C M, Kummar, S, van Tilburg, C M, Dubois, S G, Geoerger, B, Mascarenhas, L, Federman, N, Schilder, R J, Doz, F, Berlin, J D, Oh, D-Y, Bielack, S S, McDermott, R, Tan, D S, Cruickshank, S, Ku, N C, Cox, M C, Drilon, A, Hong, D S

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Reconsolidation involves histone acetylation depending on the strength of the memory von Federman, N, Fustiñana, M.S, Romano, A

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Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children von Drilon, Alexander, Laetsch, Theodore W, Kummar, Shivaani, DuBois, Steven G, Lassen, Ulrik N, Demetri, George D, Nathenson, Michael, Doebele, Robert C, Farago, Anna F, Pappo, Alberto S, Turpin, Brian, Dowlati, Afshin, Brose, Marcia S, Mascarenhas, Leo, Federman, Noah, Berlin, Jordan, El-Deiry, Wafik S, Baik, Christina, Deeken, John, Boni, Valentina, Nagasubramanian, Ramamoorthy, Taylor, Matthew, Rudzinski, Erin R, Meric-Bernstam, Funda, Sohal, Davendra P.S, Ma, Patrick C, Raez, Luis E, Hechtman, Jaclyn F, Benayed, Ryma, Ladanyi, Marc, Tuch, Brian B, Ebata, Kevin, Cruickshank, Scott, Ku, Nora C, Cox, Michael C, Hawkins, Douglas S, Hong, David S, Hyman, David M

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The Impact of State Licensing Regulations on Low-Skilled Immigrants: The Case of Vietnamese Manicurists von Federman, Maya N., Harrington, David E., Krynski, Kathy J.

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Safety and Efficacy of Stereotactic Body Radiation Therapy for Pulmonary Metastases From High-Grade Sarcomas von Mehta, N.M, Selch, M, Federman, N, Chmielowski, B, Lee, J.M, Eilber, F.C, Wang, P, Wu, J, Agazaryan, N, Lee, P

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Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors von Gounder, Mrinal, Ratan, Ravin, Alcindor, Thierry, Schöffski, Patrick, van der Graaf, Winette T., Wilky, Breelyn A., Riedel, Richard F., Lim, Allison, Smith, L. Mary, Moody, Stephanie, Attia, Steven, Chawla, Sant, D’Amato, Gina, Federman, Noah, Merriam, Priscilla, Van Tine, Brian A., Vincenzi, Bruno, Benson, Charlotte, Bui, Nam Quoc, Chugh, Rashmi, Tinoco, Gabriel, Charlson, John, Dileo, Palma, Hartner, Lee, Lapeire, Lore, Mazzeo, Filomena, Palmerini, Emanuela, Reichardt, Peter, Stacchiotti, Silvia, Bailey, Howard H., Burgess, Melissa A., Cote, Gregory M., Davis, Lara E., Deshpande, Hari, Gelderblom, Hans, Grignani, Giovanni, Loggers, Elizabeth, Philip, Tony, Pressey, Joseph G., Kummar, Shivaani, Kasper, Bernd

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Vietnamese Manicurists: Are Immigrants Displacing Natives or Finding New Nails to Polish? von Federman, Maya N., Harrington, David E., Krynski, Kathy J.

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1757P Proceedings of the think tank for osteosarcoma medical advisory board meeting von Chawla, S.P., Van Tine, B.A., Federman, N., Schwab, J., Jones, R.L., Subbiah, V., Swaney, W., Chawla, N.S., Spencer, T., Afshar, N., Hoos, W., Feldman, N., Gordon, E.M.

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1771P Blessed: Expanded yccess for DeltaRex-G in vivo gene therapy for sarcoma, pancreas and breast cancer (NCT04091295) and other solid malignancies (IND# 19130) von Chawla, S.P., Isacoff, W., Jeffrey, S., Omelchenko, N., Chawla, N.S., Agarwal, A.D., Haroun, G., Carter, R., Reed, R., Swaney, W., Hall, F.L., Federman, N., Chang, P., Song, P., Gordon, E.M.

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Hematopoietic stem cell transplantation for Diamond Blackfan anemia: a report from the Diamond Blackfan Anemia Registry von VLACHOS, A, FEDERMAN, N, REYES-HALEY, C, ABRAMSON, J, LIPTON, J. M

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WE‐E‐332‐06: Estimated Cumulative Effective Dose From PET/CT in Pediatric Patients with Malignancies von Zhang, D, Chawla, S, Nagata, K, Federman, N, Soujanya, N, Boechat, I, Angel, E, McNitt‐Gray, M

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463P Efficacy and safety of larotrectinib in a pooled analysis of patients (Pts) with tropomyosin receptor kinase (TRK) fusion cancer with an extended follow-up von McDermott, R.S., van Tilburg, C., Lin, J.J., Kummar, S., Tan, D.S.W., Albert, C.M., Berlin, J.D., Lassen, U.N., Doz, F., Geoerger, B., Mascarenhas, L., Federman, N., Norenberg, R., Dima, L., Mussi, C., De La Cuesta, E.A., Laetsch, T., Hong, D.S., Drilon, A.E.

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1620O Phase I study of TK216, a novel anti-ETS agent for Ewing sarcoma von Ludwig, J.A., Federman, N., Anderson, P., Macy, M.E., Davis, L.E., Riedel, R.F., Muscal, J.A., Daw, N.C., Ratan, R., Toretsky, J., Ianopulos, X., Hsu, F.J., Breitmeyer, J.B., Meyers, P.

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LBA2 DeFi: A phase III, randomized controlled trial of nirogacestat versus placebo for progressing desmoid tumors (DT) von Kasper, B., Ratan, R., Alcindor, T., Schoeffski, P., van der Graaf, W.T.A., Wilky, B.A., Riedel, R.F., Lim, A., Smith, L.M., Moody, S., Attia, S., Chawla, S.P., D'Amato, G., Federman, N., Van Tine, P., Van Tine, B.A., Vincenzi, B., Kummar, S., Gounder, M.M.

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The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia von Shankar, Deepa B., Cheng, Jerry C., Kinjo, Kentaro, Federman, Noah, Moore, Theodore B., Gill, Amandip, Rao, Nagesh P., Landaw, Elliot M., Sakamoto, Kathleen M.

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1955P Survival benefits of larotrectinib in an integrated dataset of patients with TRK fusion cancer von McDermott, R., van Tilburg, C.M., Farago, A.F., Kummar, S., Tan, D.S.W., Albert, C.M., Berlin, J., Lassen, U.N., Doz, F., Geoerger, B., Mascarenhas, L., Federman, N., Reeves, J.A., Dima, L., Brega, N., De La Cuesta, E., Laetsch, T.W., Hong, D.S., Drilon, A.

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136P Efficacy and safety of larotrectinib (laro) as first-line treatment for paediatric (paed) patients (pts) with TRK fusion cancer von Orbach, D., Zwaan, C.M., Albert, C.M., Federman, N., Pappo, A., Bernard-Gauthier, V., Neu, N., De La Cuesta, E.A., Laetsch, T., Zhang, Y.

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B02 The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma von Momcilovic, M., Lee, J.T., Braas, D., Graeber, T.G., Parlati, F., Demo, S., Li, R., Gricowski, M., Shuman, R., Ibarra, J., Fridman, D., St.John, M., Bernthal, N., Federman, N., Yanagawa, J., Dubinett, S.M., Sadeghi, S., Christofk, H.R., Shackelford, D.B.

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Mifamurtide: A Review of its Use in the Treatment of Osteosarcoma von Frampton, James E.

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