Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling von Eyre, Rachel, Alférez, Denis G., Santiago-Gómez, Angélica, Spence, Kath, McConnell, James C., Hart, Claire, Simões, Bruno M., Lefley, Diane, Tulotta, Claudia, Storer, Joanna, Gurney, Austin, Clarke, Noel, Brown, Mick, Howell, Sacha J., Sims, Andrew H., Farnie, Gillian, Ottewell, Penelope D., Clarke, Robert B.

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Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor von HARRISON, Hannah, FARNIE, Gillian, HOWELL, Sacha J, ROCK, Rebecca E, STYLIANOU, Spyros, BRENNAN, Keith R, BUNDRED, Nigel J, CLARKE, Robert B

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PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression von Chiang, Kelly, Zielinska, Agnieszka E., Shaaban, Abeer M., Sanchez-Bailon, Maria Pilar, Jarrold, James, Clarke, Thomas L., Zhang, Jingxian, Francis, Adele, Jones, Louise J., Smith, Sally, Barbash, Olena, Guccione, Ernesto, Farnie, Gillian, Smalley, Matthew J., Davies, Clare C.

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A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity von Shaw, Frances L., Harrison, Hannah, Spence, Katherine, Ablett, Matthew P., Simões, Bruno M., Farnie, Gillian, Clarke, Robert B.

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Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms von SINGH, Jagdeep K, FARNIE, Gillian, BUNDRED, Nigel J, SIMOES, Bruno M, SHERGILL, Amrita, LANDBERG, Goran, HOWELL, Sacha J, CLARKE, Robert B

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Discovery of an MLLT1/3 YEATS Domain Chemical Probe von Moustakim, Moses, Christott, Thomas, Monteiro, Octovia P., Bennett, James, Giroud, Charline, Ward, Jennifer, Rogers, Catherine M., Smith, Paul, Panagakou, Ioanna, Díaz‐Sáez, Laura, Felce, Suet Ling, Gamble, Vicki, Gileadi, Carina, Halidi, Nadia, Heidenreich, David, Chaikuad, Apirat, Knapp, Stefan, Huber, Kilian V. M., Farnie, Gillian, Heer, Jag, Manevski, Nenad, Poda, Gennady, Al‐awar, Rima, Dixon, Darren J., Brennan, Paul E., Fedorov, Oleg

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Focal Adhesion Kinase and Wnt Signaling Regulate Human Ductal Carcinoma In Situ Stem Cell Activity and Response to Radiotherapy von Williams, Kathryn E., Bundred, Nigel J., Landberg, Göran, Clarke, Robert B., Farnie, Gillian

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FAK inhibition alone or in combination with adjuvant therapies reduces cancer stem cell activity von Timbrell, Simon, Aglan, Hosam, Cramer, Angela, Foden, Phil, Weaver, David, Pachter, Jonathan, Kilgallon, Aoife, Clarke, Robert B., Farnie, Gillian, Bundred, Nigel J.

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PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo von Brown, Elizabeth J., Balaguer-Lluna, Leire, Cribbs, Adam P., Philpott, Martin, Campo, Leticia, Browne, Molly, Wong, Jong Fu, Oppermann, Udo, Carcaboso, Ángel M., Bullock, Alex N., Farnie, Gillian

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Combined inhibition of ErbB1/2 and Notch receptors effectively targets breast ductal carcinoma in situ (DCIS) stem/progenitor cell activity regardless of ErbB2 status von Farnie, Gillian, Willan, Pamela M, Clarke, Robert B, Bundred, Nigel J

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Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9 von Christott, Thomas, Bennett, James, Coxon, Carmen, Monteiro, Octovia, Giroud, Charline, Beke, Viktor, Felce, Suet Ling, Gamble, Vicki, Gileadi, Carina, Poda, Gennady, Al-awar, Rima, Farnie, Gillian, Fedorov, Oleg

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A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity von Ablett, Matthew P, O'Brien, Ciara S, Sims, Andrew H, Farnie, Gillian, Clarke, Robert B

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RNA-Seq analysis of early transcriptional responses to activation in the leukaemic Jurkat E6.1 T cell line von Felce, Suet Ling, Farnie, Gillian, Dustin, Michael L., Felce, James H.

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Lapatinib inhibits stem/progenitor proliferation in preclinical in vitro models of ductal carcinoma in situ (DCIS) von Farnie, Gillian, Johnson, Rachael, Williams Williams, Kathryn, Clarke, Robert, Bundred, Nigel

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Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold von Hardcastle, Ian R, Ahmed, Shafiq U, Atkins, Helen, Farnie, Gillian, Golding, Bernard T, Griffin, Roger J, Guyenne, Sabrina, Hutton, Claire, Källblad, Per, Kemp, Stuart J, Kitching, Martin S, Newell, David R, Norbedo, Stefano, Northen, Julian S, Reid, Rebecca J, Saravanan, K, Willems, Henriëtte M. G, Lunec, John

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The Mitogenic Action of Insulin-like Growth Factor I in Normal Human Mammary Epithelial Cells Requires the Epidermal Growth Factor Receptor Tyrosine Kinase von Ahmad, Tawhid, Farnie, Gillian, Bundred, Nigel J., Anderson, Neil G.

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High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant von Farnie, Gillian, Sotgia, Federica, Lisanti, Michael P

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Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction von Hardcastle, Ian R., Ahmed, Shafiq U., Atkins, Helen, Calvert, A. Hilary, Curtin, Nicola J., Farnie, Gillian, Golding, Bernard T., Griffin, Roger J., Guyenne, Sabrina, Hutton, Claire, Källblad, Per, Kemp, Stuart J., Kitching, Martin S., Newell, David R., Norbedo, Stefano, Northen, Julian S., Reid, Rebecca J., Saravanan, K., Willems, Henriëtte M.G., Lunec, John

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Mammary Stem Cells and Breast Cancer--Role of Notch Signalling von Farnie, Gillian, Clarke, Robert B

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A novel preclinical model of the normal human breast von Wilby, Anthony J., Cabral, Sara, Zoghi, Nastaran, Howell, Sacha J., Farnie, Gillian, Harrison, Hannah

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