Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evalua... von Bekker, Pirow, Dairaghi, Daniel, Seitz, Lisa, Leleti, Manmohan, Wang, Yu, Ertl, Linda, Baumgart, Trageen, Shugarts, Sarah, Lohr, Lisa, Dang, Ton, Miao, Shichang, Zeng, Yibin, Fan, Pingchen, Zhang, Penglie, Johnson, Daniel, Powers, Jay, Jaen, Juan, Charo, Israel, Schall, Thomas J

Volltext

CCX559 is a potent, orally-administered small molecule PD-L1 inhibitor that induces anti-tumor immunity von Sullivan, Kathleen M C, Vilalta, Marta, Ertl, Linda S, Wang, Yu, Dunlap, Carolyn, Ebsworth, Karen, Zhao, Bin N, Li, Shijie, Zeng, Yibin, Miao, Zhenhua, Fan, Pingchen, Mali, Venkat, Lange, Christopher, McMurtrie, Darren, Yang, Ju, Lui, Rebecca, Scamp, Ryan, Chhina, Vicky, Kumamoto, Alice, Yau, Simon, Dang, Ton, Easterday, Ashton, Liu, Shirley, Miao, Shichang, Charo, Israel, Schall, Thomas J, Zhang, Penglie

Volltext

Correction: Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Precli... von Bekker, Pirow, Dairaghi, Daniel, Seitz, Lisa, Leleti, Manmohan, Wang, Yu, Ertl, Linda, Baumgart, Trageen, Shugarts, Sarah, Lohr, Lisa, Dang, Ton, Miao, Shichang, Zeng, Yibin, Fan, Pingchen, Zhang, Penglie, Johnson, Daniel, Powers, Jay, Jaen, Juan, Charo, Israel, Schall, Thomas J

Volltext

Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo von Motani, Alykhan, Wang, Zhulun, Conn, Marion, Siegler, Karen, Zhang, Ying, Liu, Qingxiang, Johnstone, Sheree, Xu, Haoda, Thibault, Steve, Wang, Yingcai, Fan, Pingchen, Connors, Richard, Le, Hoa, Xu, Guifen, Walker, Nigel, Shan, Bei, Coward, Peter

Volltext

Discovery of a novel melanin concentrating hormone receptor 1 (MCHR1) antagonist with reduced hERG inhibition von Mihalic, Jeffrey T., Fan, Pingchen, Chen, Xiaoqi, Chen, Xi, Fu, Ying, Motani, Alykhan, Liang, Lingming, Lindstrom, Michelle, Tang, Liang, Chen, Jin-Long, Jaen, Juan, Dai, Kang, Li, Leping

Volltext

Discovery of a novel series of melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity von Mihalic, Jeffrey T., Chen, Xiaoqi, Fan, Pingchen, Chen, Xi, Fu, Ying, Liang, Lingming, Reed, Michael, Tang, Liang, Chen, Jin-Long, Jaen, Juan, Li, Leping, Dai, Kang

Volltext

Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2 von Chen, Xiaoqi, Mihalic, Jeff, Fan, Pingchen, Liang, Lingming, Lindstrom, Michelle, Wong, Sylvia, Ye, Qiuping, Fu, Ying, Jaen, Juan, Chen, Jin-Long, Dai, Kang, Li, Leping

Volltext

Stereoselective Synthesis of a MCHr1 Antagonist von Andersen, Denise, Storz, Thomas, Liu, Pingli, Wang, Xin, Li, Leping, Fan, Pingchen, Chen, Xiaoqi, Allgeier, Alan, Burgos, Alain, Tedrow, Jason, Baum, Jean, Chen, Ying, Crockett, Rich, Huang, Liang, Syed, Rashid, Larsen, Robert D, Martinelli, Mike

Volltext

The synthesis and SAR of novel diarylsulfone 11β-HSD1 inhibitors von Yan, Xuelei, Wang, Zhulun, Sudom, Athena, Cardozo, Mario, DeGraffenreid, Michael, Di, Yongmei, Fan, Pingchen, He, Xiao, Jaen, Juan C., Labelle, Marc, Liu, Jinsong, Ma, Ji, McMinn, Dustin, Miao, Shichang, Sun, Daqing, Tang, Liang, Tu, Hua, Ursu, Stefania, Walker, Nigel, Ye, Qiuping, Powers, Jay P.

Volltext

Substituted indoloquinolines as new antifungal agents von ABLORDEPPEY, Seth Y, PINGCHEN FAN, SHOUMING LI, CLARK, Alice M, HUFFORD, Charles D

Volltext

Abstract 1274: CCX559 is a potent orally-administered small molecule PD-L1 inhibitor that induces anti-tumor immunity von Li, Chris, Vilalta, Marta, Ertl, Linda S., Wang, Yu, Zeng, Yibin, Fan, Pingchen, Lange, Christopher, McMurtrie, Darren, Yang, Ju, Lui, Rebecca, Scamp, Ryan, Chhina, Vicky, Kumamoto, Alice, Ong, Ryan, Dang, Ton, Easterday, Ashton, Zhao, Niky, Liu, Shirley, Singh, Rajinder, Charo, Israel, Sullivan, Kathleen, Schall, Thomas J., Zhang, Penglie

Volltext

Abstract 5693: Anti-tumor effect of orally available small molecule PD-L1 inhibitors in a murine model of colon adenocarcinoma von Li, Shijie "Chris", Vilalta, Marta, Ertl, Linda S., Wang, Yu, Zeng, Yibin, Fan, Pingchen, Lange, Christopher, McMurtrie, Darren, Yang, Ju, Lui, Rebecca, Ong, Ryan, Chhina, Vicky, Kumamoto, Alice, Yau, Simon, Dang, Ton, Easterday, Ashton, Liu, Shirley, Singh, Rajinder, Charo, Israel, Schall, Thomas J., Zhang, Penglie

Volltext

Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3 von Li, Zhihong, Wang, Xianghong, Eksterowicz, John, Gribble, Michael W, Alba, Grace Q, Ayres, Merrill, Carlson, Timothy J, Chen, Ada, Chen, Xiaoqi, Cho, Robert, Connors, Richard V, DeGraffenreid, Michael, Deignan, Jeffrey T, Duquette, Jason, Fan, Pingchen, Fisher, Benjamin, Fu, Jiasheng, Huard, Justin N, Kaizerman, Jacob, Keegan, Kathleen S, Li, Cong, Li, Kexue, Li, Yunxiao, Liang, Lingming, Liu, Wen, Lively, Sarah E, Lo, Mei-Chu, Ma, Ji, McMinn, Dustin L, Mihalic, Jeffrey T, Modi, Kriti, Ngo, Rachel, Pattabiraman, Kanaka, Piper, Derek E, Queva, Christophe, Ragains, Mark L, Suchomel, Julia, Thibault, Steve, Walker, Nigel, Wang, Xiaodong, Wang, Zhulun, Wanska, Malgorzata, Wehn, Paul M, Weidner, Margaret F, Zhang, Alex J, Zhao, Xiaoning, Kamb, Alexander, Wickramasinghe, Dineli, Dai, Kang, McGee, Lawrence R, Medina, Julio C

Volltext

Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 3. Total Synthesis of (+)-13-Carbaartemisinin and Related Tetra- and Tricyclic Structures von Avery, Mitchell A, Fan, Pingchen, Karle, Jean M, Bonk, Jason D, Miller, Robert, Goins, D. Keith

Volltext

Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4 von Wang, Yingcai, Connors, Richard, Fan, Pingchen, Wang, Xiaodong, Wang, Zhongyu, Liu, Jiwen, Kayser, Frank, Medina, Julio C, Johnstone, Sheree, Xu, Haoda, Thibault, Stephen, Walker, Nigel, Conn, Marion, Zhang, Ying, Liu, Qingxiang, Grillo, Mark P, Motani, Alykhan, Coward, Peter, Wang, Zhulun

Volltext

Prodrugs of fused-bicyclic C5aR antagonists von SINGH, Rajinder, ZHANG, Penglie, ZENG, Yibin, MALI, Venkat Reddy, FAN, Pingchen, LUI, Rebecca M

Volltext bestellen

PRODRUGS OF FUSED-BICYCLIC C5AR ANTAGONISTS von SINGH, Rajinder, ZHANG, Penglie, ZENG, Yibin, MALI, Venkat Reddy, FAN, Pingchen, LUI, Rebecca M

Volltext bestellen

PRODRUGS OF FUSED-BICYCLIC C5AR ANTAGONISTS von SINGH, Rajinder, ZHANG, Penglie, ZENG, Yibin, MALI, Venkat Reddy, FAN, Pingchen, LUI, Rebecca M

Volltext bestellen

CCR4 ANTAGONISTS von SCAMP, Ryan J, ZHANG, Penglie, YANG, Ju, ZENG, Yibin, FAN, Pingchen, LUI, Rebecca M, WANG, Yu

Volltext bestellen

Prodrugs of fused-bicyclic c5ar antagonists von Lui, Rebecca M, Zhang, Penglie, Zeng, Yibin, Fan, Pingchen, Singh, Rajinder, Mali, Venkat Reddy

Volltext bestellen