Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway von Fan, Jianjia, Zhao, Rui Qi, Parro, Cameron, Zhao, Wenchen, Chou, Hsien-Ya, Robert, Jerome, Deeb, Tarek Z., Raynoschek, Carina, Barichievy, Samantha, Engkvist, Ola, Maresca, Marcello, Hicks, Ryan, Meuller, Johan, Moss, Stephen J., Brandon, Nicholas J., Wood, Michael W., Kulic, Iva, Wellington, Cheryl L.

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Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes von Valenza, Marta, Leoni, Valerio, Karasinska, Joanna M, Petricca, Lara, Fan, Jianjia, Carroll, Jeffrey, Pouladi, Mahmoud A, Fossale, Elisa, Nguyen, Huu Phuc, Riess, Olaf, MacDonald, Marcy, Wellington, Cheryl, DiDonato, Stefano, Hayden, Michael, Cattaneo, Elena

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ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1... von Button, Emily B, Boyce, Guilaine K, Wilkinson, Anna, Stukas, Sophie, Hayat, Arooj, Fan, Jianjia, Wadsworth, Brennan J, Robert, Jerome, Martens, Kris M, Wellington, Cheryl L

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ABCA1 influences neuroinflammation and neuronal death von Karasinska, Joanna M, de Haan, Willeke, Franciosi, Sonia, Ruddle, Piers, Fan, Jianjia, Kruit, Janine K, Stukas, Sophie, Lütjohann, Dieter, Gutmann, David H, Wellington, Cheryl L, Hayden, Michael R

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Intravenously Injected Human Apolipoprotein A‐I Rapidly Enters the Central Nervous System via the Choroid Plexus von Stukas, Sophie, Robert, Jerome, Lee, Michael, Kulic, Iva, Carr, Michael, Tourigny, Katherine, Fan, Jianjia, Namjoshi, Dhananjay, Lemke, Kalistyne, DeValle, Nicole, Chan, Jeniffer, Wilson, Tammy, Wilkinson, Anna, Chapanian, Rafi, Kizhakkedathu, Jayachandran N., Cirrito, John R., Oda, Michael N., Wellington, Cheryl L.

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An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases von Robert, Jerome, Weilinger, Nicholas L., Cao, Li-Ping, Cataldi, Stefano, Button, Emily B., Stukas, Sophie, Martin, Emma M., Seibler, Philip, Gilmour, Megan, Caffrey, Tara M., Rowe, Elyn M., Fan, Jianjia, MacVicar, Brian, Farrer, Matthew J., Wellington, Cheryl L.

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Specific Loss of Brain ABCA1 Increases Brain Cholesterol Uptake and Influences Neuronal Structure and Function von Karasinska, Joanna M, Rinninger, Franz, Lutjohann, Dieter, Ruddle, Piers, Franciosi, Sonia, Kruit, Janine K, Singaraja, Roshni R, Hirsch-Reinshagen, Veronica, Fan, Jianjia, Brunham, Liam R, Bissada, Nagat, Ramakrishnan, Rajasekhar, Wellington, Cheryl L, Parks, John S, Hayden, Michael R

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Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes von Fan, Jianjia, Zareyan, Shahab, Zhao, Wenchen, Shimizu, Yoko, Pfeifer, Tom A, Tak, Jun-Hyung, Isman, Murray B, Van den Hoven, Bernard, Duggan, Mark E, Wood, Michael W, Wellington, Cheryl L, Kulic, Iva

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The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E von Namjoshi, Dhananjay R, Martin, Georgina, Donkin, James, Wilkinson, Anna, Stukas, Sophie, Fan, Jianjia, Carr, Michael, Tabarestani, Sepideh, Wuerth, Kelli, Hancock, Robert E W, Wellington, Cheryl L

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Axl receptor tyrosine kinase is a regulator of apolipoprotein E von Zhao, Wenchen, Fan, Jianjia, Kulic, Iva, Koh, Cheryl, Clark, Amanda, Meuller, Johan, Engkvist, Ola, Barichievy, Samantha, Raynoschek, Carina, Hicks, Ryan, Maresca, Marcello, Wang, Qi, Brown, Dean G, Lok, Alvin, Parro, Cameron, Robert, Jerome, Chou, Hsien-Ya, Zuhl, Andrea M, Wood, Michael W, Brandon, Nicholas J, Wellington, Cheryl L

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Hormonal modulators of glial ABCA1 and apoE levels[S] von Fan, Jianjia, Shimizu, Yoko, Chan, Jeniffer, Wilkinson, Anna, Ito, Ayaka, Tontonoz, Peter, Dullaghan, Edie, Galea, LiisaA.M., Pfeifer, Tom, Wellington, Cheryl L.

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LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins von Hirsch-Reinshagen, Veronica, Donkin, James, Stukas, Sophie, Chan, Jennifer, Wilkinson, Anna, Fan, Jianjia, Parks, John S., Kuivenhoven, Jan Albert, Lu¨tjohann, Dieter, Pritchard, Haydn, Wellington, Cheryl L.

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Overexpression of Human ABCG1 Does Not Affect Atherosclerosis in Fat-Fed ApoE-Deficient Mice von Burgess, Braydon, Naus, Kathryn, Chan, Jeniffer, Hirsch-Reinshagen, Veronica, Tansley, Gavin, Matzke, Lisa, Chan, Benny, Wilkinson, Anna, Fan, Jianjia, Donkin, James, Balik, Danielle, Tanaka, Tracie, Ou, George, Dyer, Roger, Innis, Sheila, McManus, Bruce, Lütjohann, Dieter, Wellington, Cheryl

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An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia von Fan, Jianjia, Stukas, Sophie, Wong, Charmaine, Chan, Jennifer, May, Sharon, DeValle, Nicole, Hirsch-Reinshagen, Veronica, Wilkinson, Anna, Oda, Michael N., Wellington, Cheryl L.

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ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo von Burgess, Braydon L., Parkinson, Pamela F., Racke, Margaret M., Hirsch-Reinshagen, Veronica, Fan, Jianjia, Wong, Charmaine, Stukas, Sophie, Theroux, Louise, Chan, Jeniffer Y., Donkin, James, Wilkinson, Anna, Balik, Danielle, Christie, Brian, Poirier, Judes, Lütjohann, Dieter, DeMattos, Ronald B., Wellington, Cheryl L.

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Greasing the wheels of Aβ clearance in Alzheimer's Disease: The role of lipids and apolipoprotein E von Fan, Jianjia, Donkin, James, Wellington, Cheryl

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ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Prot... von Donkin, James J., Stukas, Sophie, Hirsch-Reinshagen, Veronica, Namjoshi, Dhananjay, Wilkinson, Anna, May, Sharon, Chan, Jeniffer, Fan, Jianjia, Collins, Jon, Wellington, Cheryl L.

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Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice von Robert, Jérôme, Stukas, Sophie, Button, Emily, Cheng, Wai Hang, Lee, Michael, Fan, Jianjia, Wilkinson, Anna, Kulic, Iva, Wright, Samuel D., Wellington, Cheryl L.

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Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-β peptide levels in vivo von Hirsch-Reinshagen, Veronica, Chan, Jennifer Y., Wilkinson, Anna, Tanaka, Tracie, Fan, Jianjia, Ou, George, Maia, Luis F., Singaraja, Roshni R., Hayden, Michael R., Wellington, Cheryl L.

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Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury von Namjoshi, Dhananjay R, Cheng, Wai Hang, McInnes, Kurt A, Martens, Kris M, Carr, Michael, Wilkinson, Anna, Fan, Jianjia, Robert, Jerome, Hayat, Arooj, Cripton, Peter A, Wellington, Cheryl L

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