TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy von Molgora, Martina, Esaulova, Ekaterina, Vermi, William, Hou, Jinchao, Chen, Yun, Luo, Jingqin, Brioschi, Simone, Bugatti, Mattia, Omodei, Andrea Salvatore, Ricci, Biancamaria, Fronick, Catrina, Panda, Santosh K., Takeuchi, Yoshiko, Gubin, Matthew M., Faccio, Roberta, Cella, Marina, Gilfillan, Susan, Unanue, Emil R., Artyomov, Maxim N., Schreiber, Robert D., Colonna, Marco

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Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation von McFarland, Adelle P., Yalin, Adam, Wang, Shuang-Yin, Cortez, Victor S., Landsberger, Tomer, Sudan, Raki, Peng, Vincent, Miller, Hannah L., Ricci, Biancamaria, David, Eyal, Faccio, Roberta, Amit, Ido, Colonna, Marco

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Delayed macrophage targeting by clodronate liposomes worsens the progression of cytokine storm syndrome von Khanna, Kunjan, Eul, Emily, Yan, Hui, Faccio, Roberta

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Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis von Ruhland, Megan K., Loza, Andrew J., Capietto, Aude-Helene, Luo, Xianmin, Knolhoff, Brett L., Flanagan, Kevin C., Belt, Brian A., Alspach, Elise, Leahy, Kathleen, Luo, Jingqin, Schaffer, Andras, Edwards, John R., Longmore, Gregory, Faccio, Roberta, DeNardo, David G., Stewart, Sheila A.

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The Interplay between the Bone and the Immune System von Brunetti, Giacomina, Faccio, Roberta, D'Amelio, Patrizia, Mori, Giorgio

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Therapy-Induced Senescence Drives Bone Loss von Yao, Zhangting, Murali, Bhavna, Ren, Qihao, Luo, Xianmin, Faget, Douglas V, Cole, Tom, Ricci, Biancamaria, Thotala, Dinesh, Monahan, Joseph, van Deursen, Jan M, Baker, Darren, Faccio, Roberta, Schwarz, Julie K, Stewart, Sheila A

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Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance von Meyer, Melissa A., Baer, John M., Knolhoff, Brett L., Nywening, Timothy M., Panni, Roheena Z., Su, Xinming, Weilbaecher, Katherine N., Hawkins, William G., Ma, Cynthia, Fields, Ryan C., Linehan, David C., Challen, Grant A., Faccio, Roberta, Aft, Rebecca L., DeNardo, David G.

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Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer von D'Amico, Lucia, Mahajan, Sahil, Capietto, Aude-Hélène, Yang, Zhengfeng, Zamani, Ali, Ricci, Biancamaria, Bumpass, David B, Meyer, Melissa, Su, Xinming, Wang-Gillam, Andrea, Weilbaecher, Katherine, Stewart, Sheila A, DeNardo, David G, Faccio, Roberta

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The microbiome restrains melanoma bone growth by promoting intestinal NK and Th1 cell homing to bone von Pal, Subhashis, Perrien, Daniel S, Yumoto, Tetsuya, Faccio, Roberta, Stoica, Andreea, Adams, Jonathan, Coopersmith, Craig M, Jones, Rheinallt M, Weitzmann, M Neale, Pacifici, Roberto

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44. A novel osteolineage-derived (Osterix+) stromal population contributes to breast cancer progression von Furesi, Giulia, Lee, Seunghyun, Eul, Emily, Faccio, Roberta

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42. Local and systemic effects of Dickkopf-1 during breast cancer progression by limiting NK cell-mediated killing von Lee, Seunghyun, Ricci, Biancamaria, Clever, David, Faccio, Roberta

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RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice von Vaira, Sergio, Alhawagri, Muhammad, Anwisye, Imani, Kitaura, Hideki, Faccio, Roberta, Novack, Deborah Veis

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Bone-Immune Cell Crosstalk: Bone Diseases von Brunetti, Giacomina, Faccio, Roberta, D'Amelio, Patrizia, Mori, Giorgio

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Conditional loss of IKKα in Osterix + cells has no effect on bone but leads to age-related loss of peripheral fat von Davis, Jennifer L., Pokhrel, Nitin Kumar, Cox, Linda, Rohatgi, Nidhi, Faccio, Roberta, Veis, Deborah J.

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39. Bone-derived Dickkopf-related protein 1 supports primary breast cancer growth and alters hematopoiesis von Eul, Emily, Ricci, Biancamaria, Lee, Seunghyun, Furesi, Giulia, Faccio, Roberta

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Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics von Ricci, Biancamaria, Tycksen, Eric, Celik, Hamza, Belle, Jad I, Fontana, Francesca, Civitelli, Roberto, Faccio, Roberta

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Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development von Luo, Xianmin, Fu, Yujie, Loza, Andrew J., Murali, Bhavna, Leahy, Kathleen M., Ruhland, Megan K., Gang, Margery, Su, Xinming, Zamani, Ali, Shi, Yu, Lavine, Kory J., Ornitz, David M., Weilbaecher, Katherine N., Long, Fanxin, Novack, Deborah V., Faccio, Roberta, Longmore, Gregory D., Stewart, Sheila A.

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Constitutive activation of NF-κB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue... von Davis, Jennifer L, Thaler, Roman, Cox, Linda, Ricci, Biancamaria, Zannit, Heather M, Wan, Fei, Faccio, Roberta, Dudakovic, Amel, van Wijnen, Andre J, Veis, Deborah J

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2. Homing of intestinal NK and Th1 cells to the tumor site restrains melanoma bone growth in a gut microbiome dependent manner von Pal, Subhashis, Perrien, Daniel S., Yumoto, Tetsuya, Faccio, Roberta, Neale Weitzmann, M., Pacifici, Roberto

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Oxytocin is an anabolic bone hormone von Tamma, Roberto, Colaianni, Graziana, Zhu, Ling-ling, DiBenedetto, Adriana, Greco, Giovanni, Montemurro, Gabriella, Patano, Nicola, Strippoli, Maurizio, Vergari, Rosaria, Mancini, Lucia, Colucci, Silvia, Grano, Maria, Faccio, Roberta, Liu, Xuan, Li, Jianhua, Usmani, Sabah, Bachar, Marilyn, Bab, Itai, Nishimori, Katsuhiko, Young, Larry J, Buettner, Christoph, Iqbal, Jameel, Sun, Li, Zaidi, Mone, Zallone, Alberta

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