A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection von Nicholson, George, Rantalainen, Mattias, Li, Jia V, Maher, Anthony D, Malmodin, Daniel, Ahmadi, Kourosh R, Faber, Johan H, Barrett, Amy, Min, Josine L, Rayner, N William, Toft, Henrik, Krestyaninova, Maria, Viksna, Juris, Neogi, Sudeshna Guha, Dumas, Marc-Emmanuel, Sarkans, Ugis, Donnelly, Peter, Illig, Thomas, Adamski, Jerzy, Suhre, Karsten, Allen, Maxine, Zondervan, Krina T, Spector, Tim D, Nicholson, Jeremy K, Lindon, John C, Baunsgaard, Dorrit, Holmes, Elaine, McCarthy, Mark I, Holmes, Chris C

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Molecular design and downstream processing of turoctocog alfa (NovoEight), a B-domain truncated factor VIII molecule von Ahmadian, Haleh, Hansen, Ernst B, Faber, Johan H, Sejergaard, Lars, Karlsson, Johan, Bolt, Gert, Hansen, Jens J, Thim, Lars

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Activities of Naphthylisoquinoline Alkaloids and Synthetic Analogs against Leishmania major von PONTE-SUCRE, Alicia, FABER, Johan H, GULDER, Tanja, KAJAHN, Inga, PEDERSEN, Sarah E. H, SCHULTHEIS, Martina, BRINGMANN, Gerhard, MOLL, Heidrun

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Ancistrocladinium A and B, the First N,C-Coupled Naphthyldihydroisoquinoline Alkaloids, from a Congolese Ancistrocladus Species von Bringmann, Gerhard, Kajahn, Inga, Reichert, Matthias, Pedersen, Sarah E. H, Faber, Johan H, Gulder, Tanja, Brun, Reto, Christensen, Søren B, Ponte-Sucre, Alicia, Moll, Heidrun, Heubl, Günther, Mudogo, Virima

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Metabolic profiling in Maturity-onset diabetes of the young (MODY) and young onset type 2 diabetes fails to detect robust urinary biomarkers von Gloyn, Anna L, Faber, Johan H, Malmodin, Daniel, Thanabalasingham, Gaya, Lam, Francis, Ueland, Per Magne, McCarthy, Mark I, Owen, Katharine R, Baunsgaard, Dorrit

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Six naphthylisoquinoline alkaloids and a related benzopyranone from a Congolese Ancistrocladus species related to Ancistrocladus congolensis von Bringmann, Gerhard, Spuziak, Joanna, Faber, Johan H., Gulder, Tanja, Kajahn, Inga, Dreyer, Michael, Heubl, Günther, Brun, Reto, Mudogo, Virima

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Membrane Interaction of the Factor VIIIa Discoidin Domains in Atomistic Detail von Madsen, Jesper J, Ohkubo, Y. Zenmei, Peters, Günther H, Faber, Johan H, Tajkhorshid, Emad, Olsen, Ole H

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Interaction Between the a3 Region of Factor VIII and the TIL’E’ Domains of the von Willebrand Factor von Dagil, Lisbeth, Troelsen, Kathrin S., Bolt, Gert, Thim, Lars, Wu, Bo, Zhao, Xin, Tuddenham, Edward G.D., Nielsen, Thomas E., Tanner, David A., Faber, Johan H., Breinholt, Jens, Rasmussen, Jakob E., Hansen, D. Flemming

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Factor VIII C1 Domain Spikes 2092–2093 and 2158–2159 Comprise Regions That Modulate Cofactor Function and Cellular Uptake von Bloem, Esther, van den Biggelaar, Maartje, Wroblewska, Aleksandra, Voorberg, Jan, Faber, Johan H., Kjalke, Marianne, Stennicke, Henning R., Mertens, Koen, Meijer, Alexander B.

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Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising “Hot-Spot” Lysine Residues von van den Biggelaar, Maartje, Madsen, Jesper J., Faber, Johan H., Zuurveld, Marleen G., van der Zwaan, Carmen, Olsen, Ole H., Stennicke, Henning R., Mertens, Koen, Meijer, Alexander B.

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The Novel Antimalarial Compound Dioncophylline C Forms a Complex with Heme in Solution von Schwedhelm, Kai F., Horstmann, Martin, Faber, Johan H., Reichert, Yana, Bringmann, Gerhard, Faber, Cornelius

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Probing the Conformational and Functional Consequences of Disulfide Bond Engineering in Growth Hormone by Hydrogen–Deuterium Exchange Mass Spectrometry Coupled to Electron Transfer... von Seger, Signe T, Breinholt, Jens, Faber, Johan H, Andersen, Mette D, Wiberg, Charlotte, Schjødt, Christine B, Rand, Kasper D

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A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders von Gandhi, Prafull S, Zivkovic, Minka, Østergaard, Henrik, Bonde, Amalie C, Elm, Torben, Løvgreen, Monika N, Schluckebier, Gerd, Johansson, Eva, Olsen, Ole H, Olsen, Eva H N, de Bus, Ian-Arris, Bloem, Karien, Alskär, Oskar, Rea, Catherine J, Bjørn, Søren E, Schutgens, Roger E, Sørensen, Benny, Urbanus, Rolf T, Faber, Johan H

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Ancistrotanzanine C and related 5,1' - and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis von Bringmann, G, Dreyer, M, Faber, J.H, Dalsgaard, P.W, Staerk, D, Jaroszewski, J.W, Ndangalasi, H, Mbago, F, Brun, R, Christensen, S.B

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Metabonomics in diabetes research von Faber, Johan H, Malmodin, Daniel, Toft, Henrik, Maher, Anthony D, Crockford, Derek, Holmes, Elaine, Nicholson, Jeremy K, Dumas, Marc E, Baunsgaard, Dorrit

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In vivo localization and identification of the antiplasmodial alkaloid dioncophylline A in the tropical liana Triphyophyllum peltatum by a combination of fluorescence, near infrare... von Frosch, Torsten, Schmitt, Michael, Schenzel, Karla, Faber, Johan H., Bringmann, Gerhard, Kiefer, Wolfgang, Popp, Jürgen

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Synthesis and Pharmacological Evaluation of Fluorescent and Photoactivatable Analogues of Antiplasmodial Naphthylisoquinolines von Bringmann, Gerhard, Gampe, Christian M, Reichert, Yanina, Bruhn, Torsten, Faber, Johan H, Mikyna, Martin, Reichert, Matthias, Leippe, Matthias, Brun, Reto, Gelhaus, Christoph

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Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniens... von Bringmann, G, Dreyer, M, Faber, J.H, Dalsgaard, P.W, Staerk, D, Jaroszewski, J.W, Ndangalasi, H, Mbago, F, Brun, R, Reichert, M

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Optimization of Human Plasma 1H NMR Spectroscopic Data Processing for High-Throughput Metabolic Phenotyping Studies and Detection of Insulin Resistance Related to Type 2 Diabetes von Maher, Anthony D, Crockford, Derek, Toft, Henrik, Malmodin, Daniel, Faber, Johan H, McCarthy, Mark I, Barrett, Amy, Allen, Maxine, Walker, Mark, Holmes, Elaine, Lindon, John C, Nicholson, Jeremy K

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Human metabolic profiles are stably controlled by genetic and environmental variation von Nicholson, George, Rantalainen, Mattias, Maher, Anthony D, Li, Jia V, Malmodin, Daniel, Ahmadi, Kourosh R, Faber, Johan H, Hallgrímsdóttir, Ingileif B, Barrett, Amy, Toft, Henrik, Krestyaninova, Maria, Viksna, Juris, Neogi, Sudeshna Guha, Dumas, Marc‐Emmanuel, Sarkans, Ugis, Silverman, Bernard W, Donnelly, Peter, Nicholson, Jeremy K, Allen, Maxine, Zondervan, Krina T, Lindon, John C, Spector, Tim D, McCarthy, Mark I, Holmes, Elaine, Baunsgaard, Dorrit, Holmes, Chris C

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