Editorial: What does experimental pharmacology and drug discovery look like in 2035? von Fabbrini, Maria Serena, Vago, Riccardo

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Plant Ribosome-Inactivating Proteins: Progesses, Challenges and Biotechnological Applications (and a Few Digressions) von Fabbrini, Maria Serena, Katayama, Miku, Nakase, Ikuhiko, Vago, Riccardo

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From Immunotoxins to Suicide Toxin Delivery Approaches: Is There a Clinical Opportunity? von Ardini, Matteo, Vago, Riccardo, Fabbrini, Maria Serena, Ippoliti, Rodolfo

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Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins von Giansanti, Francesco, Flavell, David J, Angelucci, Francesco, Fabbrini, Maria Serena, Ippoliti, Rodolfo

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Ribosome-inactivating proteins: from plant defense to tumor attack von de Virgilio, Maddalena, Lombardi, Alessio, Caliandro, Rocco, Fabbrini, Maria Serena

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Hosts for Hostile Protein Production: The Challenge of Recombinant Immunotoxin Expression von Zuppone, Stefania, Fabbrini, Maria Serena, Vago, Riccardo

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Aptamer-Driven Toxin Gene Delivery in U87 Model Glioblastoma Cells von di Leandro, Luana, Giansanti, Francesco, Mei, Sabrina, Ponziani, Sara, Colasante, Martina, Ardini, Matteo, Angelucci, Francesco, Pitari, Giuseppina, d'Angelo, Michele, Cimini, Annamaria, Fabbrini, Maria Serena, Ippoliti, Rodolfo

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Optimization of construct design and fermentation strategy for the production of bioactive ATF-SAP, a saporin based anti-tumoral uPAR-targeted chimera von Errico Provenzano, Alfredo, Posteri, Riccardo, Giansanti, Francesco, Angelucci, Francesco, Flavell, Sopsamorn U, Flavell, David J, Fabbrini, Maria Serena, Porro, Danilo, Ippoliti, Rodolfo, Ceriotti, Aldo, Branduardi, Paola, Vago, Riccardo

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Signal peptide-regulated toxicity of a plant ribosome-inactivating protein during cell stress von Marshall, Richard S, D'Avila, Francesca, Di Cola, Alessandra, Traini, Roberta, Spanò, Laura, Fabbrini, Maria Serena, Ceriotti, Aldo

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Dissecting the Entry Route of Saporin-based a-CD7 Immunotoxins in Human T-Cell Acute Lymphoblastic Leukaemia Cells von Giansanti, Francesco, Giordani, Valeria, Vago, Riccardo, Flavell, David, Flavell, Sopsamorn, Fabbrini, Maria, Ippoliti, Rodolfo

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Saporin Suicide Gene Therapy von Zarovni, Natasa, Vago, Riccardo, Fabbrini, Maria Serena

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Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems von Della Cristina, Pietro, Castagna, Monica, Lombardi, Alessio, Barison, Erika, Tagliabue, Giovanni, Ceriotti, Aldo, Koutris, Ilias, Di Leandro, Luana, Giansanti, Francesco, Vago, Riccardo, Ippoliti, Rodolfo, Flavell, Sopsamorn U, Flavell, David J, Colombatti, Marco, Fabbrini, Maria Serena

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Pichia pastoris as a host for secretion of toxic saporin chimeras von Lombardi, Alessio, Bursomanno, Sara, Lopardo, Teresa, Traini, Roberta, Colombatti, Marco, Ippoliti, Rodolfo, Flavell, David J, Flavell, Sopsamorn U, Ceriotti, Aldo, Fabbrini, Maria Serena

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Engineering a switchable toxin: the potential use of PDZ domains in the expression, targeting and activation of modified saporin variants von Giansanti, Francesco, Di Leandro, Luana, Koutris, Ilias, Pitari, Giuseppina, Fabbrini, Maria Serena, Lombardi, Alessio, Flavell, David J., Flavell, Sopsamorn U., Gianni, Stefano, Ippoliti, Rodolfo

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Endocytosis of a chimera between human pro‐urokinase and the plant toxin saporin: an unusual internalization mechanism von Ippoliti, Rodolfo, Lendaro, Eugenio, Benedetti, Pier Alberto, Torrisi, Maria Rosaria, Belleudi, Francesca, Carpani, Daniela, Soria, Marco Raffaello, Fabbrini, Maria Serena

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Endocytosis of a chimera between human pro-urokinase and the plant toxin saporin: an unusual internalization mechanism von IPPOLITI, R.

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Expression of the wild‐type and mutated vacuolar storage protein phaseolin in Xenopus oocytes reveals relationships between assembly and intracellular transport von CERIOTTI, Aldo, PEDRAZZINI, Emanuela, FABBRINI, Maria Serena, ZOPPE, Monica, BOLLINI, Roberto, VITALE, Alessandro

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The signal peptide of human preproendothelin-1 von Fabbrini, Maria Serena, Valsasina, Barbara, Nitti, Gianpaolo, Benatti, Luca, Vitale, Alessandro

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In vivo Expression of Mutant Preproendothelins: Hierarchy of Processing Events but no Strict Requirement of Trp-Val at the Processing Site von Fabbrini, Maria Serena, Vitale, Alessandro, Pedrazzini, Emanuela, Nitti, Gianpaolo, Zamai, Moreno, Tamburin, Monica, Caiolfa, Valeria R., Patrono, Carlo, Benatti, Luca

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Heterologous in vivo Processing of Human Preproendothelin 1 into Bioactive Peptides von Fabbrini, Maria Serena, Vitale, Alessandro, Patrono, Carlo, Zamai, Morenzo, Vaghi, Fabrizio, Caiolfa, Valeria, Monaco, Lucia, Benatti, Luca

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