Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors von Patrick Y. S. Lam, Jahdav, Prabhakar K., Eyermann, Charles J., Hodge, C. Nicholas, Ru, Yu, Bacheler, Lee T., Meek, James L., Otto, Michael J., Rayner, Marlene M., Wong, Y. Nancy, Chang, Chong-Hwan, Weber, Patricia C., Jackson, David A., Sharpe, Thomas R., Erickson-Viitanen, Susan

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Discovery of Potent and Selective SH2 Inhibitors of the Tyrosine Kinase ZAP-70 von Vu, Chi B, Corpuz, Evelyn G, Merry, Taylor J, Pradeepan, Selvaluxmi G, Bartlett, Catherine, Bohacek, Regine S, Botfield, Martyn C, Eyermann, Charles J, Lynch, Berkley A, MacNeil, Ian A, Ram, Mary K, van Schravendijk, Marie Rose, Violette, Shelia, Sawyer, Tomi K

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Identification of 4-Substituted 1,2,3-Triazoles as Novel Oxazolidinone Antibacterial Agents with Reduced Activity against Monoamine Oxidase A von Reck, Folkert, Zhou, Fei, Girardot, Marc, Kern, Gunther, Eyermann, Charles J, Hales, Neil J, Ramsay, Rona R, Gravestock, Michael B

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Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors:  Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies von Jadhav, Prabhakar K, Woerner, Francis J, Lam, Patrick Y. S, Hodge, C. Nicholas, Eyermann, Charles J, Man, Hon-Wah, Daneker, Wayne F, Bacheler, Lee T, Rayner, Marlene M, Meek, James L, Erickson-Viitanen, Susan, Jackson, David A, Calabrese, Joseph C, Schadt, Margaret, Chang, Chong-Hwan

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Preclinical characterization of CNS-active, mutant-selective fourth-generation EGFR inhibitors with potent activity against single, double, and triple mutant EGFR variants includin... von Zhang, S., Huang, W.S., Nadworny, S., Ye, E., Narasimhan, N., Eyermann, C.J., Dalgarno, D., Rivera, V., Shakespeare, W.

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Cyclic HIV Protease Inhibitors:  Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas von Lam, Patrick Y. S, Ru, Yu, Jadhav, Prabhakar K, Aldrich, Paul E, DeLucca, George V, Eyermann, Charles J, Chang, Chong-Hwan, Emmett, George, Holler, Edward R, Daneker, Wayne F, Li, Liangzhu, Confalone, Pat N, McHugh, Robert J, Han, Qi, Li, Renhua, Markwalder, Jay A, Seitz, Steven P, Sharpe, Thomas R, Bacheler, Lee T, Rayner, Marlene M, Klabe, Ronald M, Shum, Linyee, Winslow, Dean L, Kornhauser, David M, Jackson, David A, Erickson-Viitanen, Susan, Hodge, C. Nicholas

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Orientation of oxazolidinones in the active site of monoamine oxidase von Jones, Tadeusz Z.E., Fleming, Paul, Eyermann, Charles J., Gravestock, Michael B., Ramsay, Rona R.

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Effects of structural modifications on the intestinal permeability of angiotensin II receptor antagonists and the correlation of in vitro, in situ, and in vivo absorption von RIBADENEIRA, M. D, AUNGST, B. J, EYERMANN, C. J, SHIEW-MEI HUANG

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Core-electron binding energies for gaseous atoms and molecules von Jolly, W.L., Bomben, K.D., Eyermann, C.J.

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Molecular Recognition of Cyclic Urea HIV-1 Protease Inhibitors von Ala, Paul J., DeLoskey, Richard J., Huston, Edward E., Jadhav, Prabhakar K., Lam, Patrick Y.S., Eyermann, Charles J., Hodge, C. Nicholas, Schadt, Margaret C., Lewandowski, Frank A., Weber, Patricia C., McCabe, Denise D., Duke, Jodie L., Chang, Chong-Hwan

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Calculated and Experimental Low-Energy Conformations of Cyclic Urea HIV Protease Inhibitors von Hodge, C. Nicholas, Lam, Patrick Y. S, Eyermann, Charles J, Jadhav, Prabhakar K, Ru, Y, Fernandez, Christina H, De Lucca, George V, Chang, Chong-Hwan, Kaltenbach, Robert F, Holler, Edward R, Woerner, Francis, Daneker, Wayne F, Emmett, George, Calabrese, Joseph C, Aldrich, Paul E

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A novel phosphotyrosine mimetic 4'-carboxymethyloxy-3'-phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain von Kawahata, N, Yang, M G, Luke, G P, Shakespeare, W C, Sundaramoorthi, R, Wang, Y, Johnson, D, Merry, T, Violette, S, Guan, W, Bartlett, C, Smith, J, Hatada, M, Lu, X, Dalgarno, D C, Eyermann, C J, Bohacek, R S, Sawyer, T K

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NMR Evidence for the Displacement of a Conserved Interior Water Molecule in HIV Protease by a Non-Peptide Cyclic Urea-Based Inhibitor von Grzesiek, Stephan, Bax, Ad, Nicholson, Linda K, Yamazaki, Toshimasa, Wingfield, Paul, Stahl, Stephen J, Eyermann, Charles J, Torchia, Dennis A, Hodge, C. Nicholas

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NMR and X-ray Evidence That the HIV Protease Catalytic Aspartyl Groups Are Protonated in the Complex Formed by the Protease and a Non-Peptide Cyclic Urea-Based Inhibitor von Yamazaki, Toshimasa, Nicholson, Linda K, Wingfield, Paul, Stahl, Stephen J, Kaufman, Joshua D, Eyermann, Charles J, Hodge, C. Nicholas, Lam, Patrick Y. S, Torchia, D. A

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Study of hyperconjugation in trifluoramine oxide and related molecules using core and valence ionization potentials von Eyermann, C.J., Jolly, W.L., Xiang, S.F., Shreeve, J.M., Kinkead, S.A.

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Structural Studies of a Family of High Affinity Ligands for GPIIb/IIIa von Bach, Alvin C, Eyermann, Charles J, Gross, John D, Bower, Michael J, Harlow, Richard L, Weber, Patrica C, DeGrado, William F

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Electronic structure of HMn(CO)5, H2Fe(CO)4, and HCo(CO)4: molecular orbitals, transition energies, and photoactive states von EYERMANN, C. J, CHUNG-PHILLIPS, A

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Applications of the equivalent cores approximation. The determination of proton affinities and isocyanide-to-nitrile isomerization energies from core binding energies von Beach, David B, Eyermann, Charles J, Smit, Steven P, Xiang, Si Fen, Jolly, William L

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Novel conformationally restricted aromatic piperidines as selective sigma receptor ligands von Cain, Gary A., Christos, Thomas E., Eyermann, Charles J., Gilligan, Paul J., Grigoriadis, Dimitri E., Johnson, Alexander L., Tam, S.William

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Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain: Phosphotyrosine mimetics exploiting multifunctional group replacement chemistry von Sundaramoorthi, Raji, Kawahata, Noriyuki, Yang, Michael G., Shakespeare, William C., Metcalf III, Chester A., Wang, Yihan, Merry, Taylor, Eyermann, Charles J., Bohacek, Regine S., Narula, Surinder, Dalgarno, David C., Sawyer, Tomi K.

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