The synthesis and biodistribution of [11C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo von Hume, W. Ewan, Shingaki, Tomotaka, Takashima, Tadayuki, Hashizume, Yoshinobu, Okauchi, Takashi, Katayama, Yumiko, Hayashinaka, Emi, Wada, Yasuhiro, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Watanabe, Yasuyoshi

Volltext

Structure–activity relationships of the oxindole growth hormone secretagogues von Tokunaga, Teruhisa, Hume, W. Ewan, Nagamine, Jun, Kawamura, Tetsuya, Taiji, Mutsuo, Nagata, Ryu

Volltext

Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [11C]Metformin in Mouse von Shingaki, Tomotaka, Hume, W. Ewan, Takashima, Tadayuki, Katayama, Yumiko, Okauchi, Takashi, Hayashinaka, Emi, Wada, Yasuhiro, Cui, Yilong, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Watanabe, Yasuyoshi

Volltext

Enhanced Effect of Combined Treatment with SMP-534 (Antifibrotic Agent) and Losartan in Diabetic Nephropathy von Sugaru, Eiji, Nakagawa, Tsutomu, Ono-Kishino, Michiko, Nagamine, Jun, Tokunaga, Teruhisa, Kitoh, Makoto, Hume, W. Ewan, Nagata, Ryu, Taiji, Mutsuo

Volltext

The stereodivergent asymmetric synthesis of a range of 2-(1′-hydroxyalkyl)phenols von Davies, Stephen G., Hume, W. Ewan, Roberts, Paul M., Thomson, James E.

Volltext

SMP-534 ameliorates progression of glomerular fibrosis and urinary albumin in diabetic db/db mice von Sugaru, Eiji, Nakagawa, Tsutomu, Ono-Kishino, Michiko, Nagamine, Jun, Tokunaga, Teruhisa, Kitoh, Makoto, Hume, W Ewan, Nagata, Ryu, Taiji, Mutsuo

Volltext

SMP-534 inhibits TGF-beta-induced ECM production in fibroblast cells and reduces mesangial matrix accumulation in experimental glomerulonephritis von Sugaru, Eiji, Sakai, Mutsuko, Horigome, Kazuhiko, Tokunaga, Teruhisa, Kitoh, Makoto, Hume, W Ewan, Nagata, Ryu, Nakagawa, Tsutomu, Taiji, Mutsuo

Volltext

A concise and regioselective synthesis of 6-iodo-4-trifluoromethylisatin, an intermediate in the synthesis of the novel, non-peptidyl growth hormone secretagogue SM-130686 von Ewan Hume, W, Tokunaga, Teruhisa, Nagata, Ryu

Volltext

Amelioration of Established Diabetic Nephropathy by Combined Treatment with SMP-534 (Antifibrotic Agent) and Losartan in db/db Mice von Sugaru, Eiji, Nakagawa, Tsutomu, Ono-Kishino, Michiko, Nagamine, Jun, Tokunaga, Teruhisa, Kitoh, Makoto, Hume, W. Ewan, Nagata, Ryu, Taiji, Mutsuo

Volltext

Oxindole Derivatives as Orally Active Potent Growth Hormone Secretagogues von Tokunaga, Teruhisa, Hume, W. Ewan, Umezome, Takashi, Okazaki, Kazuhiko, Ueki, Yasuyuki, Kumagai, Kazuo, Hourai, Shinji, Nagamine, Jun, Seki, Hitoshi, Taiji, Mutsuo, Noguchi, Hiroshi, Nagata, Ryu

Volltext

SMP-534 ameliorates progression of glomerular fibrosis and urinary albumin in diabetic db/db mice von SUGARU, Eiji, NAKAGAWA, Tsutomu, ONO-KISHINO, Michiko, NAGAMINE, Jun, TOKUNAGA, Teruhisa, KITOH, Makoto, EWAN HUME, W, NAGATA, Ryu, TAIJI, Mutsuo

Volltext

Palladium-Catalysed Intramolecular Cyclisations of Olefinic Propargylic Carbonates and application to the diastereoselective synthesis of enantiomerically pure (−)-α-thujone von Oppolzer, Wolfgang, Pimm, Austen, Stammen, Blanda, Hume, W. Ewan

Volltext

SMP-534 inhibits TGF-β-induced ECM production in fibroblast cells and reduces mesangial matrix accumulation in experimental glomerulonephritis von SUGARU, Eiji, SAKAI, Mutsuko, HORIGOME, Kazuhiko, TOKUNAGA, Teruhisa, KITOH, Makoto, EWAN HUME, W, NAGATA, Ryu, NAKAGAWA, Tsutomu, TAIJI, Mutsuo

Volltext

Synthesis of Tricyclic Azakynurenic Acids as a New Class of NMDA-Glycine Antagonists Using Novel Stille Coupling Reaction von Hume, W. Ewan, Nagata, Ryu

Volltext

Smiles rearrangements promoted by complexation to chromium tricarbonyl von Davies, Stephen G, Hume, W.Ewan

Volltext

Structure-Activity Relationships of the Oxindole Growth Hormone Secretagogues von Tokunaga, Teruhisa, Hume, W. Ewan, Nagamine, Jun, Kawamura, Tetsuya, Taiji, Mutsuo, Nagata, Ryu

Volltext

OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS von TOKUNAGA, TERUHISA, UEKI, YASUYUKI, KUMAGAI, KAZUO, UMEZOME, TAKASHI, NAGATA, RYU, OKAZAKI, KAZUHIKO, HUME, W. EWAN

Volltext bestellen

Asymmetric synthesis of the enantiomers of the diarylcarbinol (1R)- and (1S)-1-(1-hydroxyphenylmethyl)-2-hydroxybenzene von Davies, Stephen G., Hume, W. Ewan

Volltext

WACHSTUMSHORMON-FREISETZENDE OXINDOLDERIVATE von TOKUNAGA, TERUHISA, UEKI, YASUYUKI, KUMAGAI, KAZUO, UMEZOME, TAKASHI, NAGATA, RYU, OKAZAKI, KAZUHIKO, HUME, W., EWAN

Volltext bestellen

OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS von TOKUNAGA, TERUHISA, UEKI, YASUYUKI, KUMAGAI, KAZUO, UMEZOME, TAKASHI, NAGATA, RYU, OKAZAKI, KAZUHIKO, HUME, W., EWAN

Volltext bestellen