Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses von Kim, Yong Chan, Zhang, Ai-Hong, Su, Yan, Rieder, Sadiye Amcaoglu, Rossi, Robert J., Ettinger, Ruth A., Pratt, Kathleen P., Shevach, Ethan M., Scott, David W.

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Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study von Ettinger, Ruth A, Buitinga, Mijke, Vandamme, Céline, Afonso, Georgia, Gomez, Rebecca, Arribas-Layton, David, Bissenova, Samal, Speake, Cate, Reijonen, Helena, Kinnunen, Tuure, Overbergh, Lut, Mallone, Roberto, Kwok, William W, James, Eddie A

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Non-Genetically Encoded Epitopes Are Relevant Targets in Autoimmune Diabetes von Nguyen, Hai, Guyer, Perrin, Ettinger, Ruth A., James, Eddie A.

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T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire von Ettinger, Ruth A., Paz, Pedro, James, Eddie A., Gunasekera, Devi, Aswad, Fred, Thompson, Arthur R., Matthews, Dana C., Pratt, Kathleen P.

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Factor VIII gene variants and inhibitor risk in African American hemophilia A patients von Gunasekera, Devi, Ettinger, Ruth A., Nakaya Fletcher, Shelley, James, Eddie A., Liu, Maochang, Barrett, John C., Withycombe, Janice, Matthews, Dana C., Epstein, Melinda S., Hughes, Richard J., Pratt, Kathleen P.

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High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance von Nguyen, Phuong-Cac T., Lewis, Kenneth B., Ettinger, Ruth A., Schuman, Jason T., Lin, Jasper C., Healey, John F., Meeks, Shannon L., Lollar, Pete, Pratt, Kathleen P.

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Phenotypes of allo- and autoimmune antibody responses to FVIII characterized by surface plasmon resonance von Lewis, Kenneth B, Hughes, Richard J, Epstein, Melinda S, Josephson, Neil C, Kempton, Christine L, Kessler, Craig M, Key, Nigel S, Howard, Tom E, Kruse-Jarres, Rebecca, Lusher, Jeanne M, Walsh, Christopher E, Watts, Raymond G, Ettinger, Ruth A, Pratt, Kathleen P

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Six amino acid residues in a 1200 Å2 interface mediate binding of factor VIII to an IgG4κ inhibitory antibody von Lin, Jasper C, Ettinger, Ruth A, Schuman, Jason T, Zhang, Ai-Hong, Wamiq-Adhami, Muhammad, Nguyen, Phuong-Cac T, Nakaya-Fletcher, Shelley M, Puranik, Komal, Thompson, Arthur R, Pratt, Kathleen P

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Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti–factor VIII immune responses von Ettinger, Ruth A., James, Eddie A., Kwok, William W., Thompson, Arthur R., Pratt, Kathleen P.

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FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity von Ettinger, Ruth A., Liberman, Joseph A., Gunasekera, Devi, Puranik, Komal, James, Eddie A., Thompson, Arthur R., Pratt, Kathleen P.

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Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene von MacMurray, Armand J, Moralejo, Daniel H, Kwitek, Anne E, Rutledge, Elizabeth A, Van Yserloo, Brian, Gohlke, Paul, Speros, Sara J, Snyder, Ben, Schaefer, Jonathan, Bieg, Sabine, Jiang, Jianjie, Ettinger, Ruth A, Fuller, Jessica, Daniels, Terri L, Pettersson, Anna, Orlebeke, Kimberly, Birren, Bruce, Jacob, Howard J, Lander, Eric S, Lernmark, Ake

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BB rat Gimap gene expression in sorted lymphoid T and B cells von Moralejo, Daniel H., Fuller, Jessica M., Rutledge, Elizabeth A., Van Yserloo, Brian, Ettinger, Ruth A., Jensen, Richard, Osborne, William, Kwitek, Anne, Lernmark, Åke

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Allelic Variation in Key Peptide-Binding Pockets Discriminates between Closely Related Diabetes-Protective and Diabetes-Susceptible HLA-DQB106 Alleles von Ettinger, Ruth A, Papadopoulos, George K, Moustakas, Antonis K, Nepom, Gerald T, Kwok, William W

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HLA-DQ Tetramers Identify Epitope-Specific T Cells in Peripheral Blood of Herpes Simplex Virus Type 2-Infected Individuals: Direct Detection of Immunodominant Antigen-Responsive Ce... von Kwok, William W, Liu, Andrew W, Novak, Erik J, Gebe, John A, Ettinger, Ruth A, Nepom, Gerald T, Reymond, Sigrid N, Koelle, David M

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A Peptide Binding Motif for HLA-DQA10102/DQB10602, the Class II MHC Molecule Associated with Dominant Protection in Insulin-Dependent Diabetes Mellitus von Ettinger, Ruth A, Kwok, William W

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Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study von Ettinger, Ruth A, Buitinga, Mijke, Vandamme, Celine, Afonso, Georgia, Gomez, Rebecca, Arribas-Layton, David, Bissenova, Samal, Speake, Cate, Reijonen, Helena, Kinnunen, Tuure, Overbergh, Lut, Mallone, Roberto, Kwok, William W, James, Eddie A

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Distinct T Cell Interactions with HLA Class II Tetramers Characterize a Spectrum of TCR Affinities in the Human Antigen-Specific T Cell Response von Reichstetter, Sandra, Ettinger, Ruth A, Liu, Andrew W, Gebe, John A, Nepom, Gerald T, Kwok, William W

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Open reading frame sequencing and structure-based alignment of polypeptides encoded by RT1-Bb, RT1-Ba, RT1-Db, and RT1-Da alleles von Ettinger, Ruth A, Moustakas, Antonis K, Lobaton, Suzanne D

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Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat von Michalkiewicz, Mieczyslaw, Michalkiewicz, Teresa, Ettinger, Ruth A, Rutledge, Elizabeth A, Fuller, Jessica M, Moralejo, Daniel H, Van Yserloo, Brian, MacMurray, Armand J, Kwitek, Anne E, Jacob, Howard J, Lander, Eric S, Lernmark, Ake

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FVIII Proteins with a Modified Immunodominant T-Cell Epitope Exhibit Reduced Immunogenicity and Normal Procoagulant Activity von Ettinger, Ruth A., Liberman, Joseph A., Gunasekera, Devi, James, Eddie A., Thompson, Arthur R., Pratt, Kathleen P.

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