Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies von Bernasconi-Elias, P, Hu, T, Jenkins, D, Firestone, B, Gans, S, Kurth, E, Capodieci, P, Deplazes-Lauber, J, Petropoulos, K, Thiel, P, Ponsel, D, Hee Choi, S, LeMotte, P, London, A, Goetcshkes, M, Nolin, E, Jones, M D, Slocum, K, Kluk, M J, Weinstock, D M, Christodoulou, A, Weinberg, O, Jaehrling, J, Ettenberg, S A, Buckler, A, Blacklow, S C, Aster, J C, Fryer, C J

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Chemotherapy augments TRAIL-induced apoptosis in breast cell lines von KEANE, M. M, ETTENBERG, S. A, NAU, M. M, RUSSELL, E. K, LIPKOWITZ, S

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Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1 von Levkowitz, Gil, Waterman, Hadassa, Ettenberg, Seth A, Katz, Menachem, Tsygankov, Alexander Y, Alroy, Iris, Lavi, Sara, Iwai, Kazuhiro, Reiss, Yuval, Ciechanover, Aaron, Lipkowitz, Stanley, Yarden, Yosef

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Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer c... von CUELLO, Mauricio, ETTENBERG, Seth A, CLARK, Amy S, KEANE, Maccon M, POSNER, Reuben H, NAU, Marion M, DENNIS, Phillip A, LIPKOWITZ, Stan

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Fas expression and function in normal and malignant breast cell lines von KEANE, M. M, ETTENBERG, S. A, LOWREY, G. A, RUSSELL, E. K, LIPKOWITZ, S

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cbl-3 : a new mammalian cbl family protein von KEANE, M. M, ETTENBERG, S. A, NAU, M. M, BANERJEE, P, CUELLO, M, PENNINGER, J, LIPKOWITZ, S

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cbl-b inhibits epidermal growth factor receptor signaling von ETTENBERG, S. A, KEANE, M. M, NAU, M. M, FRANKEL, M, WANG, L.-M, PIERCE, J. H, LIPKOWITZ, S

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Synergistic Induction of Apoptosis by the Combination of TRAIL and Chemotherapy in Chemoresistant Ovarian Cancer Cells von Cuello, Mauricio, Ettenberg, Seth A., Nau, Marion M., Lipkowitz, Stan

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The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells von KEANE, M. M, LOWREY, A, ETTENBERG, S. A, DAYTON, M. A, LIPKOWITZ, S

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N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines von Cuello, M, Coats, A O, Darko, I, Ettenberg, S A, Gardner, G J, Nau, M M, Liu, J R, Birrer, M J, Lipkowitz, S

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Cbl-b-dependent Coordinated Degradation of the Epidermal Growth Factor Receptor Signaling Complex von Ettenberg, Seth A., Magnifico, Alessandra, Cuello, Mauricio, Nau, Marion M., Rubinstein, Yaffa R., Yarden, Yosef, Weissman, Allan M., Lipkowitz, Stan

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An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin von GARNER, Andrew P, BIALUCHA, Carl U, YAN CHEN, HUIQIN WANG, JINSHENG LIANG, DAS, Rita, MOSHER, Rebecca, JIAN GU, HUANG, Alan, HAUBST, Nicole, ZEHETMEIER, Carolin, HABERL, Manuela, SPRAGUE, Elizabeth R, ELIS, Winfried, KUNZ, Christian, HEIDT, Analeah B, HERLIHY, Kara, MURTIE, Joshua, SCHULLER, Alwin, ARTEAGA, Carlos L, SELLERS, William R, ETTENBERG, Seth A, GARRETT, Joan T, QING SHENG, SHARON LI, SINESHCHEKOVA, Olga, SAXENA, Parmita, SUTTON, Cammie R, DONGSHU CHEN

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Inhibition of NF-κB activity enhances TRAIL mediated apoptosis in breast cancer cell lines von KEANE, Maccon M, RUBINSTEIN, Yaffa, CUELLO, Mauricio, ETTENBERG, Seth A, BANERJEE, Priya, NAU, Marion M, LIPKOWITZ, Stan

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WW Domain HECT E3s Target Cbl RING Finger E3s for Proteasomal Degradation von Magnifico, Alessandra, Ettenberg, Seth, Yang, Cuihong, Mariano, Jennifer, Tiwari, Swati, Fang, Shengyun, Lipkowitz, Stan, Weissman, Allan M.

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Targeting IL-17A in multiple myeloma: a potential novel therapeutic approach in myeloma von Prabhala, R H, Fulciniti, M, Pelluru, D, Rashid, N, Nigroiu, A, Nanjappa, P, Pai, C, Lee, S, Prabhala, N S, Bandi, R L, Smith, R, Lazo-Kallanian, S B, Valet, S, Raje, N, Gold, J S, Richardson, P G, Daley, J F, Anderson, K C, Ettenberg, S A, Di Padova, F, Munshi, N C

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S2-5: An Anti-HER3 Antibody That Stabilizes the Inactive Conformation Inhibits Both HER2 and Ligand Driven Tumor Growth von Garner, AP, Bialucha, CU, Chen, D, Elis, W, Kunz, C, Li, S, Murtie, J, Saxena, P, Sineshchekova, O, Sprague, E, Ettenberg, S

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Abstract OT2-07-06: Antibody-coupled T cell receptor (ACTR) engineered autologous T cells in combination with trastuzumab for the treatment of HER2-positive malignancies von O'Callaghan, KM, Shin, J, Cheung, AS, Cheema, T, Judge, C, Ranger, A, Huet, HA, Ettenberg, SA, Sachs, J, Vasconcelles, M, Motz, G

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Evaluation of Biologic End Points and Pharmacokinetics in Patients With Metastatic Breast Cancer After Treatment With Erlotinib, an Epidermal Growth Factor Receptor Tyrosine Kinase... von TAN, Antoinette R, XIAOWEI YANG, BACHARACH, Stephen L, WHATLEY, Millie, CARRASQUILLO, Jorge A, BRAHIM, Jaime S, ETTENBERG, Seth A, LIPKOWITZ, Stan, SWAIN, Sandra M, HEWITT, Stephen M, BERMAN, Arlene, LEPPER, Erin R, SPARREBOOM, Alex, PARR, Allyson L, FIGG, William D, CHOW, Catherine, STEINBERG, Seth M

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Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b von DAVIES, Gareth C, ETTENBERG, Seth A, COATS, Ashley O, MUSSANTE, Mark, RAVICHANDRAN, Sarangan, COLLINS, Jack, NAU, Marion M, LIPKOWITZ, Stan

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Elevated serum M-CSF level predicts reduced survival in metastatic breast cancer patients von Leitzel, K., Ettenberg, S., Walsh, R., Abraham, J., Modur, V., Braendle, E., Evans, D. B., Ali, S. M., Demers, L., Lipton, A.

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