Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma von Campbell, Matthew T., Matin, Surena F., Tam, Alda L., Sheth, Rahul A., Ahrar, Kamran, Tidwell, Rebecca S., Rao, Priya, Karam, Jose A., Wood, Christopher G., Tannir, Nizar M., Jonasch, Eric, Gao, Jianjun, Zurita, Amado J., Shah, Amishi Y., Jindal, Sonali, Duan, Fei, Basu, Sreyashi, Chen, Hong, Espejo, Alexsandra B., Allison, James P., Yadav, Shalini S., Sharma, Padmanee

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p53 is regulated by the lysine demethylase LSD1 von Jenuwein, Thomas, Shiekhattar, Ramin, Dorsey, Jean A, Espejo, Alexsandra B, Lee, Min Gyu, Richter, Mario, Berger, Shelley L, Bedford, Mark T, Opravil, Susanne, Huang, Jing, Sengupta, Roopsha

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Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2 von Hadjikyriacou, Andrea, Yang, Yanzhong, Espejo, Alexsandra, Bedford, Mark T., Clarke, Steven G.

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TDRD3 Is an Effector Molecule for Arginine-Methylated Histone Marks von Yang, Yanzhong, Lu, Yue, Espejo, Alexsandra, Wu, Jiacai, Xu, Wei, Liang, Shoudan, Bedford, Mark T.

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PRMT5 C-terminal Phosphorylation Modulates a 14-3-3/PDZ Interaction Switch von Espejo, Alexsandra B., Gao, Guozhen, Black, Karynne, Gayatri, Sitaram, Veland, Nicolas, Kim, Jeesun, Chen, Taiping, Sudol, Marius, Walker, Cheryl, Bedford, Mark T.

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A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse von Schotta, Gunnar, Sengupta, Roopsha, Kubicek, Stefan, Malin, Stephen, Kauer, Monika, Callén, Elsa, Celeste, Arkady, Pagani, Michaela, Opravil, Susanne, De La Rosa-Velazquez, Inti A, Espejo, Alexsandra, Bedford, Mark T, Nussenzweig, André, Busslinger, Meinrad, Jenuwein, Thomas

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MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a von Chang, Yanqi, Sun, Lidong, Kokura, Kenji, Horton, John R., Fukuda, Mikiko, Espejo, Alexsandra, Izumi, Victoria, Koomen, John M., Bedford, Mark T., Zhang, Xing, Shinkai, Yoichi, Fang, Jia, Cheng, Xiaodong

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Arginine Methylation of the Histone H3 Tail Impedes Effector Binding von Iberg, Aimee N., Espejo, Alexsandra, Cheng, Donghang, Kim, Daehoon, Michaud-Levesque, Jonathan, Richard, Stephane, Bedford, Mark T.

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Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles von Stitzlein, Lea M, Gangadharan, Achintyan, Walsh, Leslie M, Nam, Deokhwa, Espejo, Alexsandra B, Singh, Melissa M, Patel, Kareena H, Lu, Yue, Su, Xiaoping, Ezhilarasan, Ravesanker, Gumin, Joy, Singh, Sanjay, Sulman, Erik, Lang, Frederick F, Chandra, Joya

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Assembly of methylated KDM1A and CHD1 drives androgen receptor–dependent transcription and translocation von Metzger, Eric, Willmann, Dominica, McMillan, Joel, Forne, Ignasi, Metzger, Philipp, Gerhardt, Stefan, Petroll, Kerstin, von Maessenhausen, Anne, Urban, Sylvia, Schott, Anne-Kathrin, Espejo, Alexsandra, Eberlin, Adrien, Wohlwend, Daniel, Schüle, Katrin M, Schleicher, Michael, Perner, Sven, Bedford, Mark T, Jung, Manfred, Dengjel, Jörn, Flaig, Ralf, Imhof, Axel, Einsle, Oliver, Schüle, Roland

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Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14–3–3 proteins in vitro von Tetenborg, Stephan, Wang, Helen Y., Nemitz, Lena, Depping, Anne, Espejo, Alexsandra B., Aseervatham, Jaya, Bedford, Mark T., Janssen-Bienhold, Ulrike, O’Brien, John, Dedek, Karin

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Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor) von Siddiqui, Bilal A, Chapin, Brian F, Jindal, Sonali, Duan, Fei, Basu, Sreyashi, Yadav, Shalini S, Gu, Ai-Di, Espejo, Alexsandra B, Kinder, Michelle, Pettaway, Curtis A, Ward, John F, Tidwell, Rebecca S S, Troncoso, Patricia, Corn, Paul G, Logothetis, Christopher J, Knoblauch, Roland, Hutnick, Natalie, Gottardis, Marco, Drake, Charles G, Sharma, Padmanee, Subudhi, Sumit K

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Protein arginine methyl transferases-3 and -5 increase cell surface expression of cardiac sodium channel von Beltran-Alvarez, Pedro, Espejo, Alexsandra, Schmauder, Ralf, Beltran, Carlos, Mrowka, Ralf, Linke, Thomas, Batlle, Montserrat, Pérez-Villa, Félix, Pérez, Guillermo J., Scornik, Fabiana S., Benndorf, Klaus, Pagans, Sara, Zimmer, Thomas, Brugada, Ramon

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Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer von Zhao, Huajun, Ho, Po-Chun, Lo, Yuan-Hung, Espejo, Alexsandra, Bedford, Mark T, Hung, Mien-Chie, Wang, Shao-Chun

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Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks von Bua, Dennis J, Kuo, Alex J, Cheung, Peggie, Liu, Chih Long, Migliori, Valentina, Espejo, Alexsandra, Casadio, Fabio, Bassi, Christian, Amati, Bruno, Bedford, Mark T, Guccione, Ernesto, Gozani, Or

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Methylation by Set9 modulates FoxO3 stability and transcriptional activity von Calnan, Daniel R, Webb, Ashley E, White, Jamie L, Stowe, Timothy R, Goswami, Tapasree, Shi, Xiaobing, Espejo, Alexsandra, Bedford, Mark T, Gozani, Or, Gygi, Steven P, Brunet, Anne

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Mouse Models for the p53 R72P Polymorphism Mimic Human Phenotypes von FENG ZHU, DOLLE, Martijn E. T, JOHNSON, David G, BERTON, Thomas R, KUIPER, Raoul V, CAPPS, Carrie, ESPEJO, Alexsandra, MCARTHUR, Mark J, BEDFORD, Mark T, VAN STEEG, Harry, DE VRIES, Annemieke

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Zdhhc13-dependent Drp1 S-palmitoylation impacts brain bioenergetics, anxiety, coordination and motor skills von Napoli, Eleonora, Song, Gyu, Liu, Siming, Espejo, Alexsandra, Perez, Carlos J., Benavides, Fernando, Giulivi, Cecilia

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Evaluation of in vitro and in vivo efficacy of pharmacological lysine‐specific demethylase 1 (LSD1) inhibitors in glioblastoma stem cell (GSC) models von Stitzlein, Lea, Gangadharan, Achintyan, Grasse, Leslie, Espejo, Alexsandra, Singh, Melissa, Lu, Yue, Ezhilarasan, Ravesanker, Gumin, Joy, Sulman, Erik, Lang, Frederick, Chandra, Joya

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DDRE-31. EVALUATION OF HIGHLY POTENT AND SELECTIVE SINGLE-MOLECULE DUAL EGFR/PI3K INHIBITORS IN ADULT AND PEDIATRIC HIGH-GRADE GLIOMA von Gangadharan, Achintyan, Sun, Yusha, Bailey, Cavan, Carter, Trever, Espejo, Alexsandra, Whitehead, Christopher, Leopold, Judith, Chandra, Joya

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