A roadmap to target interleukin-6 in osteoarthritis von Wiegertjes, Renske, van de Loo, Fons A J, Blaney Davidson, Esmeralda N

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Sclerostin antibody enhances implant osseointegration in bone with Col1a1 mutation von Sung, Hsiao H., Kwon, Hanna H., Stephan, Chris, Reynolds, Skylar M., Dai, Zongrui, Van der Kraan, Peter M., Caird, Michelle S., Blaney Davidson, Esmeralda N., Kozloff, Kenneth M.

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Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice von Blaney Davidson, Esmeralda N, Remst, Dennis F. G, Vitters, Elly L, van Beuningen, Henk M, Blom, Arjen B, Goumans, Marie-Jose, van den Berg, Wim B, van der Kraan, Peter M

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Unravelling osteoarthritis-related synovial fibrosis: a step closer to solving joint stiffness von Remst, Dennis F G, Blaney Davidson, Esmeralda N, van der Kraan, Peter M

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Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis von Garcia de Vinuesa, Amaya, Sanchez‐Duffhues, Gonzalo, Blaney‐Davidson, Esmeralda, Caam, Arjan, Lodder, Kirsten, Ramos, Yolande, Kloppenburg, Margreet, Meulenbelt, Ingrid, Kraan, Peter, Goumans, Marie‐José, Dijke, Peter

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Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells von de Kroon, Laurie M G, Narcisi, Roberto, Blaney Davidson, Esmeralda N, Cleary, Mairéad A, van Beuningen, Henk M, Koevoet, Wendy J L M, van Osch, Gerjo J V M, van der Kraan, Peter M

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The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis von Blom, Arjen B., van den Bosch, Martijn H., Davidson, Esmeralda N. Blaney, Roth, Johannes, Vogl, Thomas, van de Loo, Fons A., Koenders, Marije, van der Kraan, Peter M., Geven, Edwin J., van Lent, Peter L.

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Catabolic Factors and Osteoarthritis-Conditioned Medium Inhibit Chondrogenesis of Human Mesenchymal Stem Cells von Heldens, Genoveva T.H., Blaney Davidson, Esmeralda N., Vitters, Elly L., Schreurs, B. Willem, Piek, Ester, van den Berg, Wim B., van der Kraan, Peter M.

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Separating friend from foe: Inhibition of TGF-β-induced detrimental SMAD1/5/9 phosphorylation while maintaining protective SMAD2/3 signaling in OA chondrocytes von Thielen, Nathalie G.M., van Caam, Arjan P.M., v. Beuningen, Henk M., Vitters, Elly L., van den Bosch, Martijn H.J., Koenders, Marije I., van de Loo, Fons A.J., Blaney Davidson, Esmeralda N., van der Kraan, Peter M.

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SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells von de Kroon, Laurie M. G., Narcisi, Roberto, van den Akker, Guus G. H., Vitters, Elly L., Blaney Davidson, Esmeralda N., van Osch, Gerjo J. V. M., van der Kraan, Peter M.

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Early pain in females is linked to late pathological features in murine experimental osteoarthritis von Valdrighi, Natália, Blom, Arjen B, van Beuningen, Henk M, Vitters, Elly L, Helsen, Monique M, Walgreen, Birgitte, van Lent, Peter L E M, Koenders, Marije I, van der Kraan, Peter M, van de Loo, Fons A J, Blaney Davidson, Esmeralda N

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A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis von DER KRAAN, Peter M.van, BLANEY DAVIDSON, Esmeralda N, VAN DEN BERG, Wim B

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Innate Immunity at the Core of Sex Differences in Osteoarthritic Pain? von Valdrighi, Natália, Vago, Juliana P, Blom, Arjen B, van de Loo, Fons A J, Blaney Davidson, Esmeralda N

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Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8 von van den Bosch, Martijn H., Blom, Arjen B., van Lent, Peter L., van Beuningen, Henk M., Blaney Davidson, Esmeralda N., van der Kraan, Peter M., van den Berg, Wim B.

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Milk extracellular vesicles accelerate osteoblastogenesis but impair bone matrix formation von Oliveira, Marina C., Arntz, Onno J., Blaney Davidson, Esmeralda N., van Lent, Peter L.E.M., Koenders, Marije I., van der Kraan, Peter M., van den Berg, Wim B., Ferreira, Adaliene V.M., van de Loo, Fons A.J.

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Sex Differences in Pain Sensitivity in a Dutch Cohort: Cross-Sectional and Web-Based Multidimensional Study von Smits, Rachel J H, van der Wal, Selina E I, van Boekel, Regina L M, Timmerman, Hans, Bronkhorst, Ewald M, Abrar, Diana, Vissers, Kris C P, Blaney Davidson, Esmeralda N, Steegers, Monique A H

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Innate Immunity and Sex: Distinct Inflammatory Profiles Associated with Murine Pain in Acute Synovitis von Valdrighi, Natália, Blom, Arjen B, Vago, Juliana P, van Beuningen, Henk M, Vitters, Elly L, Helsen, Monique M, Walgreen, Birgitte, Arntz, Onno J, Koenders, Marije I, van der Kraan, Peter M, Blaney Davidson, Esmeralda N, van de Loo, Fons A J

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Interleukin 1 β-induced SMAD2/3 linker modifications are TAK1 dependent and delay TGFβ signaling in primary human mesenchymal stem cells von van den Akker, Guus G., van Beuningen, Henk M., Vitters, Elly L., Koenders, Marije I., van de Loo, Fons A., van Lent, Peter L., Blaney Davidson, Esmeralda N., van der Kraan, Peter M.

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Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling von Blaney Davidson, Esmeralda N, Vitters, Elly L, van Lent, Peter L E M, van de Loo, Fons A J, van den Berg, Wim B, van der Kraan, Peter M

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Identification of TGFβ-related genes regulated in murine osteoarthritis and chondrocyte hypertrophy by comparison of multiple microarray datasets von de Kroon, Laurie M.G., van den Akker, Guus G.H., Brachvogel, Bent, Narcisi, Roberto, Belluoccio, Daniele, Jenner, Florien, Bateman, John F., Little, Christopher B., Brama, Pieter A.J., Blaney Davidson, Esmeralda N., van der Kraan, Peter M., van Osch, Gerjo J.V.M.

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